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fenofibrate and Infarction, Middle Cerebral Artery

fenofibrate has been researched along with Infarction, Middle Cerebral Artery in 4 studies

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Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.

Research Excerpts

ExcerptRelevanceReference
"Fenofibrate treatment has neuroprotective effects on middle cerebral artery infarcts."5.46Neuroprotective Effects of Chronic Fenofibrate Treatment via Modulating the Immunoreactivity of Cleaved Caspase-3 in Stroke Induced by Transient Middle Cerebral Artery Occlusion Rat Model. ( Altintas, MO; Altintas, O; Antar, V; Asil, T; Aydin, MS; Baran, O; Esrefoglu, M, 2017)
"Fenofibrate treatment has neuroprotective effects on middle cerebral artery infarcts."1.46Neuroprotective Effects of Chronic Fenofibrate Treatment via Modulating the Immunoreactivity of Cleaved Caspase-3 in Stroke Induced by Transient Middle Cerebral Artery Occlusion Rat Model. ( Altintas, MO; Altintas, O; Antar, V; Asil, T; Aydin, MS; Baran, O; Esrefoglu, M, 2017)
"We conclude that PPARα agonist treatment prior to stroke is neuroprotective in males but not females."1.43Sex differences and the role of PPAR alpha in experimental stroke. ( Chen, Y; Dotson, AL; Manning, D; Nguyen, H; Offner, H; Saugstad, JA; Wang, J, 2016)
"A 1-h intraluminal thread middle cerebral artery occlusion (MCAO) model followed by a 6-h reperfusion was performed in C57/BL6 mice."1.42The role of PPAR activation during the systemic response to brain injury. ( Anthony, DC; Bordet, R; Burns, L; Guevel, B; Ladds, E; Laprais, M; Losey, P, 2015)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Losey, P1
Ladds, E1
Laprais, M1
Guevel, B1
Burns, L1
Bordet, R2
Anthony, DC1
Dotson, AL1
Wang, J1
Chen, Y1
Manning, D1
Nguyen, H1
Saugstad, JA1
Offner, H1
Altintas, O1
Altintas, MO1
Aydin, MS1
Baran, O1
Antar, V1
Esrefoglu, M1
Asil, T1
Deplanque, D1
Gelé, P1
Pétrault, O1
Six, I1
Furman, C1
Bouly, M1
Nion, S1
Dupuis, B1
Leys, D1
Fruchart, JC1
Cecchelli, R1
Staels, B1
Duriez, P1

Other Studies

4 other studies available for fenofibrate and Infarction, Middle Cerebral Artery

ArticleYear
The role of PPAR activation during the systemic response to brain injury.
    Journal of neuroinflammation, 2015, 05-22, Volume: 12

    Topics: Analysis of Variance; Animals; Brain Injuries; Chemokine CXCL1; Chemokine CXCL10; Disease Models, An

2015
Sex differences and the role of PPAR alpha in experimental stroke.
    Metabolic brain disease, 2016, Volume: 31, Issue:3

    Topics: Animals; Brain; Female; Fenofibrate; Hypolipidemic Agents; Infarction, Middle Cerebral Artery; Male;

2016
Neuroprotective Effects of Chronic Fenofibrate Treatment via Modulating the Immunoreactivity of Cleaved Caspase-3 in Stroke Induced by Transient Middle Cerebral Artery Occlusion Rat Model.
    Turkish neurosurgery, 2017, Volume: 27, Issue:4

    Topics: Animals; Brain; Caspase 3; Caspase Inhibitors; Disease Models, Animal; Fenofibrate; Infarction, Midd

2017
Peroxisome proliferator-activated receptor-alpha activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Jul-16, Volume: 23, Issue:15

    Topics: Animals; Apolipoproteins E; Cerebral Infarction; Cerebrovascular Circulation; Disease Models, Animal

2003