Page last updated: 2024-10-27

fenofibrate and Hyperplasia

fenofibrate has been researched along with Hyperplasia in 4 studies

Pharmavit: a polyvitamin product, comprising vitamins A, D2, B1, B2, B6, C, E, nicotinamide, & calcium pantothene; may be a promising agent for application to human populations exposed to carcinogenic and genetic hazards of ionizing radiation; RN from CHEMLINE

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
" We assessed lipid profiles, plasma CET activity, and in-stent intimal hyperplasia after fenofibrate treatment in patients who underwent elective coronary stenting."9.14Effects of fenofibrate on lipid profiles, cholesterol ester transfer activity, and in-stent intimal hyperplasia in patients after elective coronary stenting. ( Daida, H; Hiki, M; Kiyanagi, T; Kume, A; Kurata, T; Miyauchi, K; Miyazaki, T; Mokuno, H; Okazaki, S; Sato, H; Shimada, K; Sumiyoshi, K; Tanimoto, K, 2010)
"Fenofibrate-treated group showed a significant reduction in neointimal formation (0."5.37Inhibitory effect of fenofibrate on neointima hyperplasia via G(0)/G(1) arrest of cell proliferation. ( Kim, DW; Kim, TJ; Kwon, JS; Lee, JJ; Lim, Y; Myung, CS; Yu, JY; Yun, YP; Zhang, WY, 2011)
"Fenofibrate was tested in vivo, in 30 coronary arteries of 10 pigs (1g/day, orally) and was compared to placebo."5.33Efficacy of peroxisome proliferative activated receptor (PPAR)-alpha ligands, fenofibrate, on intimal hyperplasia and constrictive remodeling after coronary angioplasty in porcine models. ( Aihara, K; Daida, H; Kasai, T; Miyauchi, K; Yokoyama, T, 2006)
"The PPAR-gamma ligand rosiglitazone, but not the PPAR-alpha ligand fenofibrate, decreases intimal hyperplasia following balloon injury in both fatty and lean Zucker rats."3.72Differential effects of peroxisome proliferator activator receptor-alpha and gamma ligands on intimal hyperplasia after balloon catheter-induced vascular injury in Zucker rats. ( Desouza, CV; Diez, J; Dunne, B; Fonseca, VA; Matta, AS; McNamara, DB; Murthy, SN, 2003)
"Fenofibrate was tested in vivo, in 30 coronary arteries of 10 pigs (1g/day, orally) and was compared to placebo."1.33Efficacy of peroxisome proliferative activated receptor (PPAR)-alpha ligands, fenofibrate, on intimal hyperplasia and constrictive remodeling after coronary angioplasty in porcine models. ( Aihara, K; Daida, H; Kasai, T; Miyauchi, K; Yokoyama, T, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyazaki, T1
Shimada, K1
Miyauchi, K2
Kume, A1
Tanimoto, K1
Kiyanagi, T1
Sumiyoshi, K1
Hiki, M1
Mokuno, H1
Okazaki, S1
Sato, H1
Kurata, T1
Daida, H2
Lee, JJ1
Yu, JY1
Zhang, WY1
Kim, TJ1
Lim, Y1
Kwon, JS1
Kim, DW1
Myung, CS1
Yun, YP1
Desouza, CV1
Murthy, SN1
Diez, J1
Dunne, B1
Matta, AS1
Fonseca, VA1
McNamara, DB1
Kasai, T1
Yokoyama, T1
Aihara, K1

Trials

1 trial available for fenofibrate and Hyperplasia

ArticleYear
Effects of fenofibrate on lipid profiles, cholesterol ester transfer activity, and in-stent intimal hyperplasia in patients after elective coronary stenting.
    Lipids in health and disease, 2010, Oct-25, Volume: 9

    Topics: Aged; Angioplasty, Balloon, Coronary; Cholesterol Esters; Cholesterol, HDL; Cholesterol, LDL; Drug-E

2010

Other Studies

3 other studies available for fenofibrate and Hyperplasia

ArticleYear
Inhibitory effect of fenofibrate on neointima hyperplasia via G(0)/G(1) arrest of cell proliferation.
    European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1

    Topics: Angioplasty, Balloon; Animals; Becaplermin; Cell Proliferation; Cyclin D; Cyclin E; Cyclin-Dependent

2011
Differential effects of peroxisome proliferator activator receptor-alpha and gamma ligands on intimal hyperplasia after balloon catheter-induced vascular injury in Zucker rats.
    Journal of cardiovascular pharmacology and therapeutics, 2003, Volume: 8, Issue:4

    Topics: Animals; Biomarkers; Blood Glucose; Body Weight; Catheterization; Cholesterol; Diabetes Mellitus, Ty

2003
Efficacy of peroxisome proliferative activated receptor (PPAR)-alpha ligands, fenofibrate, on intimal hyperplasia and constrictive remodeling after coronary angioplasty in porcine models.
    Atherosclerosis, 2006, Volume: 188, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Animals; Coronary Restenosis; Coronary Vessels; Fenofibrate; Hyperpl

2006