fenofibrate has been researched along with Glial Cell Tumors in 3 studies
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| Excerpt | Relevance | Reference |
|---|---|---|
| " Then, we explored the molecular mechanism by which lncRNA HOTAIR regulates PPARα in cell lines in vitro and in a nude mouse glioma model in vivo and explored the effect of the combined application of HOTAIR knockdown and fenofibrate treatment on glioma invasion." | 8.02 | The lipid-lowering drug fenofibrate combined with si-HOTAIR can effectively inhibit the proliferation of gliomas. ( Dai, X; Huang, B; Ni, S; Nyalali, AMK; Sun, J; Xu, F; Zhang, K; Zhao, H; Zhu, W, 2021) |
| "The effects of fenofibrate on Glioma cell motility, IGF-I receptor (IGF-IR) signaling, PPARalpha activity, reactive oxygen species (ROS) metabolism, mitochondrial potential, and ATP production were analyzed in human glioma cell lines." | 7.76 | ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARalpha -mediated inhibition of glioma cell motility in vitro. ( Del Valle, L; Drukala, J; Grabacka, M; Madeja, Z; Reiss, K; Urbanska, K; Wilk, A; Wybieralska, E, 2010) |
| "Fenofibrate treatment of HGG cells robustly diminished the expression of key signaling pathways, including NF-κB and cyclin D1." | 5.40 | Characterization of fenofibrate-mediated anti-proliferative pro-apoptotic effects on high-grade gliomas and anti-invasive effects on glioma stem cells. ( Binello, E; Emdad, L; Germano, IM; Kothari, H; Mormone, E, 2014) |
| " Then, we explored the molecular mechanism by which lncRNA HOTAIR regulates PPARα in cell lines in vitro and in a nude mouse glioma model in vivo and explored the effect of the combined application of HOTAIR knockdown and fenofibrate treatment on glioma invasion." | 4.02 | The lipid-lowering drug fenofibrate combined with si-HOTAIR can effectively inhibit the proliferation of gliomas. ( Dai, X; Huang, B; Ni, S; Nyalali, AMK; Sun, J; Xu, F; Zhang, K; Zhao, H; Zhu, W, 2021) |
| "The effects of fenofibrate on Glioma cell motility, IGF-I receptor (IGF-IR) signaling, PPARalpha activity, reactive oxygen species (ROS) metabolism, mitochondrial potential, and ATP production were analyzed in human glioma cell lines." | 3.76 | ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARalpha -mediated inhibition of glioma cell motility in vitro. ( Del Valle, L; Drukala, J; Grabacka, M; Madeja, Z; Reiss, K; Urbanska, K; Wilk, A; Wybieralska, E, 2010) |
| "Fenofibrate treatment of HGG cells robustly diminished the expression of key signaling pathways, including NF-κB and cyclin D1." | 1.40 | Characterization of fenofibrate-mediated anti-proliferative pro-apoptotic effects on high-grade gliomas and anti-invasive effects on glioma stem cells. ( Binello, E; Emdad, L; Germano, IM; Kothari, H; Mormone, E, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, W | 1 |
| Zhao, H | 1 |
| Xu, F | 1 |
| Huang, B | 1 |
| Dai, X | 1 |
| Sun, J | 1 |
| Nyalali, AMK | 1 |
| Zhang, K | 1 |
| Ni, S | 1 |
| Binello, E | 1 |
| Mormone, E | 1 |
| Emdad, L | 1 |
| Kothari, H | 1 |
| Germano, IM | 1 |
| Drukala, J | 1 |
| Urbanska, K | 1 |
| Wilk, A | 1 |
| Grabacka, M | 1 |
| Wybieralska, E | 1 |
| Del Valle, L | 1 |
| Madeja, Z | 1 |
| Reiss, K | 1 |
3 other studies available for fenofibrate and Glial Cell Tumors
| Article | Year |
|---|---|
The lipid-lowering drug fenofibrate combined with si-HOTAIR can effectively inhibit the proliferation of gliomas.
Topics: Adult; Aged; Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromatin Immuno | 2021 |
Characterization of fenofibrate-mediated anti-proliferative pro-apoptotic effects on high-grade gliomas and anti-invasive effects on glioma stem cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Proliferation; Fenofibrate; Flow Cytometry | 2014 |
ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARalpha -mediated inhibition of glioma cell motility in vitro.
Topics: Adenosine Triphosphate; Base Sequence; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Fenofibrate | 2010 |