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fenofibrate and Diabetic Cardiomyopathies

fenofibrate has been researched along with Diabetic Cardiomyopathies in 4 studies

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Diabetic Cardiomyopathies: Diabetes complications in which VENTRICULAR REMODELING in the absence of CORONARY ATHEROSCLEROSIS and hypertension results in cardiac dysfunctions, typically LEFT VENTRICULAR DYSFUNCTION. The changes also result in myocardial hypertrophy, myocardial necrosis and fibrosis, and collagen deposition due to impaired glucose tolerance.

Research Excerpts

ExcerptRelevanceReference
"Fenofibrate treatment had no detectable effect on serum A-FABP level (P > 0."2.77Long-term fenofibrate therapy increases fibroblast growth factor 21 and retinol-binding protein 4 in subjects with type 2 diabetes. ( Barter, PJ; Brown, C; Jenkins, AJ; Keech, AC; O'Connell, R; Ong, KL; Rye, KA; Sullivan, DR; Xu, A, 2012)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, W2
Lai, Y1
Wang, L1
Xia, Y1
Zhao, X1
Yu, M1
Li, Y1
Zhang, Y1
Ye, H1
Zhang, J1
Cheng, Y1
Gu, J1
Wang, S1
Zhou, S1
Wang, Y1
Tan, Y1
Feng, W1
Fu, Y1
Mellen, N1
Cheng, R1
Ma, J1
Zhang, C1
Li, Z1
Cai, L1
Williams, KH1
Sullivan, DR2
Nicholson, GC1
George, J1
Jenkins, AJ2
Januszewski, AS1
Gebski, VJ1
Manning, P1
Tan, YM1
Donoghoe, MW1
Ehnholm, C1
Young, S1
O'Brien, R1
Buizen, L1
Twigg, SM1
Keech, AC2
Ong, KL1
Rye, KA1
O'Connell, R1
Brown, C1
Xu, A1
Barter, PJ1

Trials

2 trials available for fenofibrate and Diabetic Cardiomyopathies

ArticleYear
Opposite associations between alanine aminotransferase and γ-glutamyl transferase levels and all-cause mortality in type 2 diabetes: Analysis of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study.
    Metabolism: clinical and experimental, 2016, Volume: 65, Issue:5

    Topics: Aged; Alanine Transaminase; Australia; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus, Type

2016
Long-term fenofibrate therapy increases fibroblast growth factor 21 and retinol-binding protein 4 in subjects with type 2 diabetes.
    The Journal of clinical endocrinology and metabolism, 2012, Volume: 97, Issue:12

    Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Double-Blind Method; Female; Fenofibrate

2012

Other Studies

2 other studies available for fenofibrate and Diabetic Cardiomyopathies

ArticleYear
Astragalus polysaccharides repress myocardial lipotoxicity in a PPARalpha-dependent manner in vitro and in vivo in mice.
    Journal of diabetes and its complications, 2015, Volume: 29, Issue:2

    Topics: Animals; Astragalus propinquus; Cardiotonic Agents; Cell Line; Diabetic Cardiomyopathies; Dietary Su

2015
Fenofibrate increases cardiac autophagy via FGF21/SIRT1 and prevents fibrosis and inflammation in the hearts of Type 1 diabetic mice.
    Clinical science (London, England : 1979), 2016, Volume: 130, Issue:8

    Topics: Animals; Autophagy; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Ty

2016