fenofibrate has been researched along with Chagas Cardiomyopathy in 3 studies
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Chagas Cardiomyopathy: A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fenofibrate treatment restored to normal values the ejection and shortening fractions, left ventricular end-diastolic, left ventricular end-systolic diameter, and isovolumic relaxation time." | 5.46 | Treatment with Fenofibrate plus a low dose of Benznidazole attenuates cardiac dysfunction in experimental Chagas disease. ( Cevey, ÁC; Donato, M; Gelpi, RJ; Goren, NB; Mirkin, GA; Penas, FN; Rada, MJ, 2017) |
| "Fenofibrate treatment restored to normal values the ejection and shortening fractions, left ventricular end-diastolic, left ventricular end-systolic diameter, and isovolumic relaxation time." | 1.46 | Treatment with Fenofibrate plus a low dose of Benznidazole attenuates cardiac dysfunction in experimental Chagas disease. ( Cevey, ÁC; Donato, M; Gelpi, RJ; Goren, NB; Mirkin, GA; Penas, FN; Rada, MJ, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cevey, ÁC | 3 |
| Pieralisi, AV | 2 |
| Donato, M | 3 |
| Rada, J | 2 |
| Gelpi, RJ | 2 |
| Mirkin, GA | 3 |
| Goren, NB | 3 |
| Penas, FN | 3 |
| Alba Soto, C | 1 |
| Gelpi, R | 1 |
| Rada, MJ | 1 |
3 other studies available for fenofibrate and Chagas Cardiomyopathy
| Article | Year |
|---|---|
Macrophages Mediate Healing Properties of Fenofibrate in Experimental Chagasic Cardiomyopathy.
Topics: Cardiomyopathies; Chagas Cardiomyopathy; Chagas Disease; Fenofibrate; Humans; Macrophages | 2023 |
IL-10-Dependent and -Independent Mechanisms Are Involved in the Cardiac Pathology Modulation Mediated by Fenofibrate in an Experimental Model of Chagas Heart Disease.
Topics: Animals; Cells, Cultured; Chagas Cardiomyopathy; Creatine Kinase; Disease Models, Animal; Fenofibrat | 2020 |
Treatment with Fenofibrate plus a low dose of Benznidazole attenuates cardiac dysfunction in experimental Chagas disease.
Topics: Animals; Chagas Cardiomyopathy; Chagas Disease; Diastole; Fenofibrate; Fibrosis; Humans; Inflammatio | 2017 |