fenofibrate has been researched along with Brain Ischemia in 5 studies
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Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pre-treatment with fenofibrate and pioglitazone in addition to their combination improved neurobehavioral dysfunction, reduced cerebral infarct volume, attenuated inflammatory and apoptotic markers and ameliorated histopathological changes in I/R injured rats." | 1.56 | The impact of single and combined PPAR-α and PPAR-γ activation on the neurological outcomes following cerebral ischemia reperfusion. ( Abdelrehim, AB; Ahmed, AF; Heeba, GH; Shehata, AHF, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shehata, AHF | 1 |
| Ahmed, AF | 1 |
| Abdelrehim, AB | 1 |
| Heeba, GH | 1 |
| Ouk, T | 1 |
| Gautier, S | 1 |
| Pétrault, M | 1 |
| Montaigne, D | 1 |
| Maréchal, X | 1 |
| Masse, I | 1 |
| Devedjian, JC | 1 |
| Deplanque, D | 1 |
| Bastide, M | 1 |
| Nevière, R | 1 |
| Duriez, P | 1 |
| Staels, B | 1 |
| Pasquier, F | 1 |
| Leys, D | 1 |
| Bordet, R | 1 |
| Xuan, AG | 1 |
| Chen, Y | 1 |
| Long, DH | 1 |
| Zhang, M | 1 |
| Ji, WD | 1 |
| Zhang, WJ | 1 |
| Liu, JH | 1 |
| Hong, LP | 1 |
| He, XS | 1 |
| Chen, WL | 1 |
| Guo, Q | 2 |
| Wang, G | 2 |
| Namura, S | 2 |
| Liu, X | 1 |
5 other studies available for fenofibrate and Brain Ischemia
| Article | Year |
|---|---|
The impact of single and combined PPAR-α and PPAR-γ activation on the neurological outcomes following cerebral ischemia reperfusion.
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Drug Therapy | 2020 |
Effects of the PPAR-α agonist fenofibrate on acute and short-term consequences of brain ischemia.
Topics: Animals; Behavior, Animal; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; | 2014 |
PPARα Agonist Fenofibrate Ameliorates Learning and Memory Deficits in Rats Following Global Cerebral Ischemia.
Topics: Animals; Brain Ischemia; Cell Death; Cytokines; Fenofibrate; Gene Expression Regulation; Hippocampus | 2015 |
Fenofibrate improves cerebral blood flow after middle cerebral artery occlusion in mice.
Topics: Animals; Antipyrine; Arterial Occlusive Diseases; Autoradiography; Brain Ischemia; Capillaries; Cere | 2010 |
Chronic treatment with fibrates elevates superoxide dismutase in adult mouse brain microvessels.
Topics: Animals; Brain; Brain Ischemia; Fenofibrate; Gemfibrozil; Male; Mice; Mice, Inbred C57BL; Mice, Knoc | 2010 |