fenofibrate has been researched along with Brain Injuries in 4 studies
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Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 1-h intraluminal thread middle cerebral artery occlusion (MCAO) model followed by a 6-h reperfusion was performed in C57/BL6 mice." | 1.42 | The role of PPAR activation during the systemic response to brain injury. ( Anthony, DC; Bordet, R; Burns, L; Guevel, B; Ladds, E; Laprais, M; Losey, P, 2015) |
| "Treatment with fenofibrate (given p." | 1.33 | Fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, exerts neuroprotective effects in traumatic brain injury. ( Besson, VC; Chen, XR; Marchand-Verrecchia, C; Plotkine, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Losey, P | 1 |
| Ladds, E | 1 |
| Laprais, M | 1 |
| Guevel, B | 1 |
| Burns, L | 1 |
| Bordet, R | 1 |
| Anthony, DC | 1 |
| Chen, XR | 3 |
| Besson, VC | 3 |
| Beziaud, T | 1 |
| Plotkine, M | 3 |
| Marchand-Leroux, C | 2 |
| Marchand-Verrecchia, C | 1 |
| Palmier, B | 1 |
| Garcia, Y | 1 |
4 other studies available for fenofibrate and Brain Injuries
| Article | Year |
|---|---|
The role of PPAR activation during the systemic response to brain injury.
Topics: Analysis of Variance; Animals; Brain Injuries; Chemokine CXCL1; Chemokine CXCL10; Disease Models, An | 2015 |
Combination therapy with fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, and simvastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, on experimental traumatic brain injury.
Topics: Animals; Brain Injuries; Disease Models, Animal; Drug Therapy, Combination; Fenofibrate; Hydroxymeth | 2008 |
Fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, exerts neuroprotective effects in traumatic brain injury.
Topics: Animals; Brain Edema; Brain Injuries; Disease Models, Animal; Dose-Response Relationship, Drug; Ence | 2005 |
Neurological recovery-promoting, anti-inflammatory, and anti-oxidative effects afforded by fenofibrate, a PPAR alpha agonist, in traumatic brain injury.
Topics: Aldehydes; Animals; Anti-Inflammatory Agents; Antioxidants; Brain; Brain Injuries; Cyclooxygenase 2; | 2007 |