fenofibrate has been researched along with Astrocytoma, Grade IV in 8 studies
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| Excerpt | Relevance | Reference |
|---|---|---|
| "Fenofibrate (FF) is a common lipid-lowering drug and a potent agonist of the peroxisome proliferator-activated receptor alpha (PPARα)." | 5.42 | Molecular mechanisms of fenofibrate-induced metabolic catastrophe and glioblastoma cell death. ( Culicchia, F; Dean, M; Grabacka, M; Marrero, L; Mullinax, J; Ochoa, A; Parsons, C; Peruzzi, F; Reiss, K; Wilk, A; Wyczechowska, D; Zapata, A, 2015) |
| "Fenofibrate is a lipid-lowering drug and an agonist of the peroxisome proliferator-activated receptor alpha (PPARα)." | 5.42 | NF-κB/RelA-PKM2 mediates inhibition of glycolysis by fenofibrate in glioblastoma cells. ( Chen, X; Han, D; Hu, Q; Liu, N; Wang, X; Wang, Y; Wei, W; You, Y; Yu, T; Zhang, J; Zhang, Y, 2015) |
| "Fenofibrate, a well-known normolipidemic drug, has been shown to exert strong anticancer effects against tumors of neuroectodermal origin including glioblastoma." | 3.81 | Fenofibrate subcellular distribution as a rationale for the intracranial delivery through biodegradable carrier. ( Ayyala, R; Blake, DA; Culicchia, F; Grabacka, M; John, VT; Ponnusamy, T; Reiss, K; Rutkowska, M; Vashistha, H; Waligorski, P; Wilk, A; Wisniewska-Becker, A; Wyczechowska, D; Zapata, A, 2015) |
| "Fenofibrate (FF) is a common lipid-lowering drug and a potent agonist of the peroxisome proliferator-activated receptor alpha (PPARα)." | 1.42 | Molecular mechanisms of fenofibrate-induced metabolic catastrophe and glioblastoma cell death. ( Culicchia, F; Dean, M; Grabacka, M; Marrero, L; Mullinax, J; Ochoa, A; Parsons, C; Peruzzi, F; Reiss, K; Wilk, A; Wyczechowska, D; Zapata, A, 2015) |
| "Fenofibrate is a lipid-lowering drug and an agonist of the peroxisome proliferator-activated receptor alpha (PPARα)." | 1.42 | NF-κB/RelA-PKM2 mediates inhibition of glycolysis by fenofibrate in glioblastoma cells. ( Chen, X; Han, D; Hu, Q; Liu, N; Wang, X; Wang, Y; Wei, W; You, Y; Yu, T; Zhang, J; Zhang, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, C | 1 |
| Lai, SW | 1 |
| Shen, CK | 1 |
| Chen, CW | 1 |
| Tsai, CF | 1 |
| Liu, YS | 1 |
| Lu, DY | 1 |
| Huang, BR | 1 |
| Stalinska, J | 1 |
| Houser, L | 1 |
| Rak, M | 1 |
| Colley, SB | 1 |
| Reiss, K | 4 |
| Jursic, BS | 1 |
| Kast, RE | 1 |
| Hill, QA | 1 |
| Wion, D | 1 |
| Mellstedt, H | 1 |
| Focosi, D | 1 |
| Karpel-Massler, G | 1 |
| Heiland, T | 1 |
| Halatsch, ME | 1 |
| Wilk, A | 3 |
| Wyczechowska, D | 2 |
| Zapata, A | 2 |
| Dean, M | 1 |
| Mullinax, J | 2 |
| Marrero, L | 1 |
| Parsons, C | 1 |
| Peruzzi, F | 1 |
| Culicchia, F | 2 |
| Ochoa, A | 1 |
| Grabacka, M | 3 |
| Han, DF | 1 |
| Zhang, JX | 1 |
| Wei, WJ | 1 |
| Tao, T | 1 |
| Hu, Q | 2 |
| Wang, YY | 1 |
| Wang, XF | 1 |
| Liu, N | 2 |
| You, YP | 1 |
| Waligorski, P | 1 |
| Blake, DA | 1 |
| Rutkowska, M | 1 |
| Vashistha, H | 1 |
| Ayyala, R | 1 |
| Ponnusamy, T | 1 |
| John, VT | 1 |
| Wisniewska-Becker, A | 1 |
| Han, D | 1 |
| Wei, W | 1 |
| Chen, X | 1 |
| Zhang, Y | 1 |
| Wang, Y | 1 |
| Zhang, J | 1 |
| Wang, X | 1 |
| Yu, T | 1 |
| You, Y | 1 |
| Urbanska, K | 1 |
| Marcinkiewicz, C | 1 |
| Impastato, D | 1 |
| Estrada, JJ | 1 |
1 review available for fenofibrate and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Glioblastoma-synthesized G-CSF and GM-CSF contribute to growth and immunosuppression: Potential therapeutic benefit from dapsone, fenofibrate, and ribavirin.
Topics: Bone Marrow Cells; Brain; Cell Proliferation; Dapsone; Fenofibrate; Glioblastoma; Granulocyte Colony | 2017 |
7 other studies available for fenofibrate and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Fenofibrate inhibits hypoxia-inducible factor-1 alpha and carbonic anhydrase expression through activation of AMP-activated protein kinase/HO-1/Sirt1 pathway in glioblastoma cells.
Topics: AMP-Activated Protein Kinases; Carbonic Anhydrases; Fenofibrate; Glioblastoma; Humans; Hypoxia; Hypo | 2021 |
Exploring anticancer activity of structurally modified benzylphenoxyacetamide (BPA); I: Synthesis strategies and computational analyses of substituted BPA variants with high anti-glioblastoma potential.
Topics: Acetamides; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Cell Surv | 2019 |
Molecular mechanisms of fenofibrate-induced metabolic catastrophe and glioblastoma cell death.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Astrocytes; Brain Neoplasms; Cell Death; Cel | 2015 |
Fenofibrate induces G0/G1 phase arrest by modulating the PPARα/FoxO1/p27 kip pathway in human glioblastoma cells.
Topics: Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; | 2015 |
Fenofibrate subcellular distribution as a rationale for the intracranial delivery through biodegradable carrier.
Topics: Animals; Biodegradable Plastics; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Carriers; Female; Fe | 2015 |
NF-κB/RelA-PKM2 mediates inhibition of glycolysis by fenofibrate in glioblastoma cells.
Topics: Animals; Blotting, Western; Carrier Proteins; Cell Line, Tumor; Female; Fenofibrate; Glioblastoma; G | 2015 |
Fenofibrate-induced nuclear translocation of FoxO3A triggers Bim-mediated apoptosis in glioblastoma cells in vitro.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Line, Tumor; Cell Nucleolus; E | 2012 |