Page last updated: 2024-10-27

fenofibrate and Arteriosclerosis

fenofibrate has been researched along with Arteriosclerosis in 41 studies

Pharmavit: a polyvitamin product, comprising vitamins A, D2, B1, B2, B6, C, E, nicotinamide, & calcium pantothene; may be a promising agent for application to human populations exposed to carcinogenic and genetic hazards of ionizing radiation; RN from CHEMLINE

Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.

Research Excerpts

ExcerptRelevanceReference
" It has been proposed that the elevated serum uric acid levels are linked to other risk factors, such as hypertension, dyslipidaemia and diabetes."3.70Management of hypertension and dyslipidaemia in patients presenting with hyperuricaemia: case histories. ( Elisaf, MS; Milionis, HJ, 2000)
"Twenty-two patients with mixed hyperlipidemia participated."2.70Folate supplementation prevents plasma homocysteine increase after fenofibrate therapy. ( Ceska, R; Grauová, B; Kozich, V; Melenovský, V; Stulc, T, 2001)
"A fenofibrate-induced increase of HDL-C in 20 low-HDL subjects was associated with a significant reduction of plasma sICAM-1 and sE-selectin concentrations."2.70Elevated soluble cellular adhesion molecules in subjects with low HDL-cholesterol. ( Calabresi, L; Dmitrieff, C; Franceschini, G; Gomaraschi, M; Omoboni, L; Villa, B, 2002)
"Fenofibrate is a broad spectrum lipid-lowering agent able to produce substantial reductions in plasma triglyceride and low density lipoprotein (LDL) and an increase in high density lipoprotein (HDL)."2.40Overview of fenofibrate. ( Packard, CJ, 1998)
"Fenofibrate treatment in apo E-KO mice paradoxically increased total cholesterol and TG by 65% and 44%, respectively, and decreased HDL-cholesterol levels by 35% as compared with controls."1.33Paradoxical effects of fenofibrate and nicotinic acid in apo E-deficient mice. ( Bahadori, B; Declercq, V; Khademi, H; Moghadasian, MH; Moshtaghi-Kashanian, GR; Yeganeh, B, 2005)
"The prevention and treatment of coronary heart disease is a major challenge in the overall management of the patient with type 2 diabetes."1.31Status report of lipid-lowering trials in diabetes. ( Armitage, J; Betteridge, DJ; Colhoun, H, 2000)
"Twenty patients with uncomplicated hyperlipidemia but no atherosclerosis, 20 patients with hyperlipidemia plus clear atherosclerosis, and 40 matched controls were studied."1.31Plasma vascular endothelial growth factor and its receptor Flt-1 in patients with hyperlipidemia and atherosclerosis and the effects of fluvastatin or fenofibrate. ( Belgore, FM; Blann, AD; Conri, C; Constans, J; Lip, GY, 2001)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.88)18.7374
1990's14 (34.15)18.2507
2000's25 (60.98)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duez, H1
Chao, YS1
Hernandez, M1
Torpier, G1
Poulain, P1
Mundt, S1
Mallat, Z1
Teissier, E1
Burton, CA1
Tedgui, A1
Fruchart, JC1
Fiévet, C1
Wright, SD1
Staels, B2
Srivastava, RA1
Dierkes, J1
Westphal, S1
Luley, C1
Jokinen, V1
Ukkola, O1
Airaksinen, KE1
Koistinen, JM1
Ikäheimo, MJ1
Kesäniemi, YA1
Huikuri, HV1
Watts, GF1
Tsimihodimos, V1
Kostoula, A1
Kakafika, A1
Bairaktari, E1
Tselepis, AD1
Mikhailidis, DP1
Elisaf, M1
Yamazaki, H1
Fujino, H1
Kanazawa, M1
Tamaki, T1
Sato, F1
Suzuki, M1
Kitahara, M1
Ruban, NV1
Zhao, SP1
Li, J1
Xu, Z1
Wu, J1
Li, Q1
Ye, H1
Sebestjen, M1
Keber, I1
Zegura, B1
Simcic, S1
Bozic, M1
Fressart, MM1
Stegnar, M1
Yeganeh, B2
Moshtaghi-Kashanian, GR2
Declercq, V2
Moghadasian, MH2
Koh, KK1
Quon, MJ1
Han, SH1
Chung, WJ1
Ahn, JY1
Seo, YH1
Choi, IS1
Shin, EK1
Khademi, H1
Bahadori, B1
Segarra Domènech, J1
Santafé Oroz, J1
Kritchevsky, D1
Singer, D1
Klurfeld, DM1
Saitoh, K2
Mori, T2
Kasai, H2
Nagayama, T2
Tsuchiya, A1
Ohbayashi, S2
Schonfeld, G1
Millán Núñez Cortés, J1
Alvarez-Sala Walther, LA1
de Oya Otero, M1
Packard, CJ3
Madej, A2
Okopien, B2
Kowalski, J2
Zielinski, M2
Wysocki, J2
Szygula, B1
Kalina, Z2
Herman, ZS1
Szyguła, B1
Herman, Z1
Sinzinger, H1
Marx, N3
Sukhova, GK1
Collins, T1
Libby, P2
Plutzky, J2
Stejskal, D1
Růzicka, V1
Bartek, J1
Bratus', VV1
Talaieva, TV1
Lomakovs'kyĭ, OM1
Tretiak, IV1
Radalovs'ka, NV1
Betteridge, DJ1
Colhoun, H1
Armitage, J1
Deighan, CJ1
Caslake, MJ1
McConnell, M1
Boulton-Jones, JM1
Milionis, HJ1
Elisaf, MS1
Xie, ML1
Gu, ZL1
Chen, KJ1
Zhou, WX1
Guo, CY1
Yamashita, T1
Nakamura, H1
Blann, AD1
Belgore, FM1
Constans, J1
Conri, C1
Lip, GY1
Hombach, V2
Stulc, T1
Melenovský, V1
Grauová, B1
Kozich, V1
Ceska, R1
Kehrle, B1
Kohlhammer, K1
Grüb, M1
Koenig, W1
Calabresi, L1
Gomaraschi, M1
Villa, B1
Omoboni, L1
Dmitrieff, C1
Franceschini, G1
Ruhn, G1
Slimane, MN1
Bouslama, A1
Maatoug, F1
Hammami, M1
Ben Farhat, MH1
Ol'binskaia, LI1
Vartanova, OA1
Aleksandrovskaia, TN1
Shaldaeva, VV1

Reviews

10 reviews available for fenofibrate and Arteriosclerosis

ArticleYear
Fenofibrate-induced hyperhomocysteinaemia: clinical implications and management.
    Drug safety, 2003, Volume: 26, Issue:2

    Topics: Arteriosclerosis; Fenofibrate; Folic Acid; Humans; Hyperhomocysteinemia; Hypolipidemic Agents; Kidne

2003
[Pharmacological and pharmacokinetic features and clinical effects of pitavastatin (Livalo Tablet)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2004, Volume: 123, Issue:5

    Topics: Animals; Arteriosclerosis; Cholesterol; Cholesterol, VLDL; Citrus paradisi; Clinical Trials as Topic

2004
[Pharmacologic therapy of atherosclerosis (I). Current possibilities].
    Medicina clinica, 1983, Nov-26, Volume: 81, Issue:17

    Topics: Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Clofibrate; Clofibric Acid; Fenofibrate; Ge

1983
The effects of fibrates on lipoprotein and hemostatic coronary risk factors.
    Atherosclerosis, 1994, Volume: 111, Issue:2

    Topics: Arteriosclerosis; Bezafibrate; Blood Coagulation; Clofibric Acid; Coronary Disease; Fenofibrate; Fib

1994
[Fenofibrate and arteriosclerosis. The new developments of the last 5 years].
    Revista clinica espanola, 1995, Volume: 195, Issue:12

    Topics: Arteriosclerosis; Clinical Trials as Topic; Fenofibrate; Humans; Hypolipidemic Agents; Lipids; Throm

1995
Overview of fenofibrate.
    European heart journal, 1998, Volume: 19 Suppl A

    Topics: Apolipoprotein C-III; Apolipoproteins C; Arteriosclerosis; Coronary Disease; Fenofibrate; Humans; Hy

1998
[Antilipemic agents and atherothrombosis. Effects of antilipemic agents on blood platelet function, coagulation and fibrinolysis].
    Deutsche medizinische Wochenschrift (1946), 1998, Sep-18, Volume: 123, Issue:38

    Topics: Anticholesteremic Agents; Antiporters; Arteriosclerosis; Bezafibrate; Blood Coagulation; Blood Coagu

1998
[Fenofibrate].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 3

    Topics: Animals; Arteriosclerosis; Coronary Disease; Fenofibrate; Humans; Hyperlipidemias; Hypolipidemic Age

2001
[Peroxisome proliferator-activated receptors (PPARs) in the vessel wall: new regulators of gene expression in vascular cells].
    Zeitschrift fur Kardiologie, 2001, Volume: 90, Issue:7

    Topics: Animals; Arteriosclerosis; Chromans; Clinical Trials as Topic; Coronary Disease; Diabetes Mellitus,

2001
[ Lipids--lipoproteins--apolipoproteins--risk markers in atherosclerosis].
    La Tunisie medicale, 1992, Volume: 70, Issue:2

    Topics: Adult; Apolipoproteins; Arteriosclerosis; Biomarkers; Fenofibrate; Humans; Lipoproteins; Middle Aged

1992

Trials

10 trials available for fenofibrate and Arteriosclerosis

ArticleYear
Temporal changes in cardiovascular autonomic regulation in type II diabetic patients: association with coronary risk variables and progression of coronary artery disease.
    Annals of medicine, 2003, Volume: 35, Issue:3

    Topics: Adult; Aged; Arteriosclerosis; Autonomic Nervous System; Coronary Angiography; Diabetes Mellitus, Ty

2003
Effect of fenofibrate on serum inflammatory markers in patients with high triglyceride values.
    Journal of cardiovascular pharmacology and therapeutics, 2004, Volume: 9, Issue:1

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Arteriosclerosis; Biomarkers; C-Reactive Prot

2004
Statin and fibrate treatment of combined hyperlipidemia: the effects on some novel risk factors.
    Thrombosis and haemostasis, 2004, Volume: 92, Issue:5

    Topics: Adult; Arteriosclerosis; Blood Coagulation; Blood Coagulation Factors; Body Weight; C-Reactive Prote

2004
Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia.
    Journal of the American College of Cardiology, 2005, May-17, Volume: 45, Issue:10

    Topics: Arteriosclerosis; Atorvastatin; Brachial Artery; Cross-Over Studies; Double-Blind Method; Drug Thera

2005
Effects of fenofibrate on plasma cytokine concentrations in patients with atherosclerosis and hyperlipoproteinemia IIb.
    International journal of clinical pharmacology and therapeutics, 1998, Volume: 36, Issue:6

    Topics: Adult; Arteriosclerosis; Cytokines; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hypol

1998
[Levels of tumor necrosis factor alpha in serum of patients with hyperlipoproteinemia IIB before and after micronized fenofibrate therapy].
    Polskie Archiwum Medycyny Wewnetrznej, 1998, Volume: 99, Issue:4

    Topics: Adult; Apolipoproteins B; Arteriosclerosis; Cholesterol; Drug Compounding; Female; Fenofibrate; Huma

1998
[Serum leptin, early atherosclerosis and hypolipidemia (a new, previously undescribed effect of pravastatin, a hypolipemic agent)].
    Vnitrni lekarstvi, 1998, Volume: 44, Issue:10

    Topics: Adipose Tissue; Age of Onset; Arteriosclerosis; Body Mass Index; Female; Fenofibrate; Humans; Hypoli

1998
Comparative effects of cerivastatin and fenofibrate on the atherogenic lipoprotein phenotype in proteinuric renal disease.
    Journal of the American Society of Nephrology : JASN, 2001, Volume: 12, Issue:2

    Topics: Arteriosclerosis; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cross-Over Studies; Female;

2001
Folate supplementation prevents plasma homocysteine increase after fenofibrate therapy.
    Nutrition (Burbank, Los Angeles County, Calif.), 2001, Volume: 17, Issue:9

    Topics: Arteriosclerosis; Dietary Supplements; Drug Synergism; Drug Therapy, Combination; Fenofibrate; Folic

2001
Elevated soluble cellular adhesion molecules in subjects with low HDL-cholesterol.
    Arteriosclerosis, thrombosis, and vascular biology, 2002, Apr-01, Volume: 22, Issue:4

    Topics: Analysis of Variance; Arteriosclerosis; Cholesterol, HDL; Cross-Over Studies; Double-Blind Method; E

2002

Other Studies

21 other studies available for fenofibrate and Arteriosclerosis

ArticleYear
Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice.
    The Journal of biological chemistry, 2002, Dec-13, Volume: 277, Issue:50

    Topics: Animals; Apolipoprotein A-I; Apolipoproteins E; Arteriosclerosis; Cholesterol; Fenofibrate; Humans;

2002
Estrogen-induced regulation of the ATP-binding cassette transporter A1 (ABCA1) in mice: a possible mechanism of atheroprotection by estrogen.
    Molecular and cellular biochemistry, 2002, Volume: 240, Issue:1-2

    Topics: Animals; Apolipoprotein A-I; Arteriosclerosis; ATP-Binding Cassette Transporters; Cholic Acid; Estra

2002
Regulation of endothelial nitric oxide synthase by PPAR agonists: molecular and clinical perspectives.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:4

    Topics: Arteriosclerosis; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Fenofibrate; Gene Expre

2004
[Systemic inflammatory process as an etiological factor in increase of atherogenic potential of plasma].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2004, Volume: 50, Issue:2

    Topics: Animals; Arteriosclerosis; Disease Models, Animal; Fenofibrate; Hypolipidemic Agents; Lipid Peroxide

2004
Fenofibrate inhibits thrombogenic and fibrinolytic factors expression in adipose tissue of atherosclerotic rabbits.
    Clinica chimica acta; international journal of clinical chemistry, 2004, Volume: 349, Issue:1-2

    Topics: Adipose Tissue; Animals; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Diet; Enzyme-Linked Im

2004
Combination of dietary phytosterols plus niacin or fenofibrate: effects on lipid profile and atherosclerosis in apo E-KO mice.
    The Journal of nutritional biochemistry, 2005, Volume: 16, Issue:4

    Topics: Animals; Apolipoproteins E; Arteriosclerosis; Body Weight; Cholesterol; Cholesterol, HDL; Diet; Feno

2005
Paradoxical effects of fenofibrate and nicotinic acid in apo E-deficient mice.
    Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:1

    Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Body Weight; Cholesterol, Dietary; Cholesterol,

2005
Influence of hypocholesterolemic drugs on aortic cholesterol esterase in rabbits.
    Pharmacological research communications, 1984, Volume: 16, Issue:6

    Topics: Animals; Anticholesteremic Agents; Aorta; Arteriosclerosis; Carboxylic Ester Hydrolases; Cholesterol

1984
[Anti-atheromatous effects of fenofibrate, a hypolipidemic drug. I: Anti-atheromatous effects are independent of its hypolipidemic effect in cholesterol-fed rabbits].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1995, Volume: 106, Issue:1

    Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Diet, Atherogenic; Disease Models, Animal; Fenofibrate;

1995
[Anti-atheromatous effects of fenofibrate, a hypolipidemic drug. II: Anti-atheromatous effects are independent of its hypolipidemic effect in hereditary hyperlipidemic rabbits].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1995, Volume: 106, Issue:1

    Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Fenofibrate; Gene Deletion; Hyperlipidemias; Hypolipidem

1995
LDL subfractions and atherogenicity: an hypothesis from the University of Glasgow.
    Current medical research and opinion, 1996, Volume: 13, Issue:7

    Topics: Arteriosclerosis; Cholesterol; Coronary Disease; Fenofibrate; Humans; Hypercholesterolemia; Hypolipi

1996
PPARalpha activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells.
    Circulation, 1999, Jun-22, Volume: 99, Issue:24

    Topics: Anticholesteremic Agents; Arteriosclerosis; Carotid Arteries; Cell Adhesion; Dose-Response Relations

1999
[Modified lipoproteins--their types and role in atherogenesis].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2000, Volume: 46, Issue:2

    Topics: Adult; Animals; Arteriosclerosis; Child; Child, Preschool; Chronic Disease; Coronary Artery Disease;

2000
Status report of lipid-lowering trials in diabetes.
    Current opinion in lipidology, 2000, Volume: 11, Issue:6

    Topics: Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Clinical Trials as Topic; Coronary Disease

2000
Management of hypertension and dyslipidaemia in patients presenting with hyperuricaemia: case histories.
    Current medical research and opinion, 2000, Volume: 16, Issue:3

    Topics: Antihypertensive Agents; Arteriosclerosis; Benzothiadiazines; Diuretics; Female; Fenofibrate; Humans

2000
Effect of lipanthyl on mRNA expression of endothelin-1 and nitric-oxide synthase in atherosclerotic vessel wall in rabbits.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:5

    Topics: Animals; Aorta, Abdominal; Arteriosclerosis; Endothelin-1; Fenofibrate; Hypolipidemic Agents; Male;

2000
Plasma vascular endothelial growth factor and its receptor Flt-1 in patients with hyperlipidemia and atherosclerosis and the effects of fluvastatin or fenofibrate.
    The American journal of cardiology, 2001, May-15, Volume: 87, Issue:10

    Topics: Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Endothelial Growth Factors; Fatty Acids, Mo

2001
Choice of lipid-regulating drugs.
    The Medical letter on drugs and therapeutics, 2001, May-28, Volume: 43, Issue:1105

    Topics: Apolipoproteins; Arteriosclerosis; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Drug Intera

2001
PPAR activators as antiinflammatory mediators in human T lymphocytes: implications for atherosclerosis and transplantation-associated arteriosclerosis.
    Circulation research, 2002, Apr-05, Volume: 90, Issue:6

    Topics: Anti-Inflammatory Agents; Arteriosclerosis; CD4-Positive T-Lymphocytes; Cells, Cultured; Fenofibrate

2002
Relation between arteriographically diagnosed femoral atherosclerosis and serum lipids. Prevalence and treatment in hyperlipidaemic subjects.
    Acta radiologica. Supplementum, 1992, Volume: 378 ( Pt 3)

    Topics: Adult; Aged; Aorta, Abdominal; Aortic Aneurysm; Arteriosclerosis; Drug Therapy, Combination; Femoral

1992
[The clinico-biochemical activity and tolerance of the hypolipidemic preparation lipanthyl].
    Terapevticheskii arkhiv, 1991, Volume: 63, Issue:8

    Topics: Arteriosclerosis; Drug Evaluation; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperl

1991