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fenofibrate and Apolipoprotein B-100, Familial Defective

fenofibrate has been researched along with Apolipoprotein B-100, Familial Defective in 72 studies

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Research Excerpts

ExcerptRelevanceReference
"To assess the efficacy and safety of coadministration of fenofibrate (NanoCrystal(R)) and ezetimibe in patients with type IIb dyslipidemia and the metabolic syndrome compared with administration of fenofibrate and ezetimibe alone (ClinicalTrials."9.14Efficacy and safety of coadministration of fenofibrate and ezetimibe compared with each as monotherapy in patients with type IIb dyslipidemia and features of the metabolic syndrome: a prospective, randomized, double-blind, three-parallel arm, multicenter, ( Ansquer, JC; Bekaert, I; Guy, M; Hanefeld, M; Simon, A, 2009)
"To evaluate the effect of micronised fenofibrate on serum paraoxonase (PON) and lipoprotein levels in coronary heart disease patients with type IIb hyperlipidemia."7.72The effect of micronised fenofibrate on paraoxonase activity in patients with coronary heart disease. ( Balogh, Z; Boda, J; Harangi, M; Illyés, L; Kovács, P; Paragh, G; Seres, I; Szilvássy, Z, 2003)
"Fibrinogen in plasma was reduced from 3."5.29[The effect of micronized fenofibrate on lipid parameters and fibrinogen in heterozygous familial hypercholesterolemia and familial combined hyperlipidemia]. ( Ceska, R; Haas, T; Kvasilová, M; Kvasnicka, J; Procházková, R; Sobra, J, 1996)
"To assess the efficacy and safety of coadministration of fenofibrate (NanoCrystal(R)) and ezetimibe in patients with type IIb dyslipidemia and the metabolic syndrome compared with administration of fenofibrate and ezetimibe alone (ClinicalTrials."5.14Efficacy and safety of coadministration of fenofibrate and ezetimibe compared with each as monotherapy in patients with type IIb dyslipidemia and features of the metabolic syndrome: a prospective, randomized, double-blind, three-parallel arm, multicenter, ( Ansquer, JC; Bekaert, I; Guy, M; Hanefeld, M; Simon, A, 2009)
"To investigate the lipoprotein effect of fenofibrate in hypercholesterolemia or combined hyperlipidemia (types II A and II B hyperlipidemias, respectively), 240 patients were recruited and 227 randomized to a double-blind randomized trial lasting 24 weeks and 192 patients continued to participate in an open-label phase for another 24 weeks."5.06Effects of fenofibrate on plasma lipoproteins in hypercholesterolemia and combined hyperlipidemia. ( Brown, WV; Dujovne, CA; Farquhar, JW; Feldman, EB; Goldberg, AC; Grundy, SM; Knopp, RH; Lasser, NL; Mellies, MJ; Palmer, RH, 1987)
"To evaluate the effect of micronised fenofibrate on serum paraoxonase (PON) and lipoprotein levels in coronary heart disease patients with type IIb hyperlipidemia."3.72The effect of micronised fenofibrate on paraoxonase activity in patients with coronary heart disease. ( Balogh, Z; Boda, J; Harangi, M; Illyés, L; Kovács, P; Paragh, G; Seres, I; Szilvássy, Z, 2003)
"Fenofibrate effect on plasma lipids and lipoproteins was studied in 23 patients with primary hyperlipoproteinemias (HLP): 12 with familial hypercholesterolemia (FH), 5 with combined HLP and 6 with Type III HLP."3.67Long term-effect of fenofibrate on lipoprotein level and composition in different types of genetic hyperlipidemias. ( Baggio, G; Ciuffetti, G; Crepaldi, G; Fellin, R; Gabelli, C; Gasparotto, A; Senin, U; Valerio, G, 1986)
"The atorvastatin regimen was marginally but not significantly better than simvastatin-fenofibrate in improving the LDL:HDL ratio, LDL:apoB and and apolipoprotein B:A1 ratios."2.69High-dose atorvastatin therapy in severe heterozygous familial hypercholesterolaemia. ( Crook, MA; Lumb, PJ; Semra, YK; Wierzbicki, AS, 1998)
"Simvastatin was associated with statistically significantly greater (p < or = 0."2.68Comparison of the efficacy of simvastatin and standard fibrate therapy in the treatment of primary hypercholesterolemia and combined hyperlipidemia. ( Baigts, F; Bruckert, E; De Gennes, JL; Malbecq, W, 1995)
" At the same time the pharmacokinetics was studied to check whether this new dosage schedule would give a therapeutic plasma levels of fenofibrate."2.66Effect of a single daily dose treatment of fenofibrate on plasma lipoproteins in hyperlipoproteinaemia IIb. ( Balestreri, R; Bertolini, S; Carozzi, A; Cotta Ramusino, AM; Daga, A; Degl'Innocenti, ML; Elicio, N; Fusi, MG, 1988)
"Ciprofibrate has the benefit of a long half-life and may also be administered in the form of a single daily dose to patients suffering from major type II hyperlipoproteinaemia."2.66Comparative evaluation of the effects of ciprofibrate and fenofibrate on lipids, lipoproteins and apoproteins A and B. ( Bakir, R; Chanu, B; Djian, F; Goy-Loeper, J; Rouffy, J, 1985)
" Micronized fenofibrate, a new formulation chemically identical to the parent compound, has improved pharmacokinetic parameters which increase absorption, provide more stable plasma levels, and thus dosage can be decreased."2.39The fibrates in clinical practice: focus on micronised fenofibrate. ( Shepherd, J, 1994)
"Dysbetalipoproteinemia (dysb) and familial hypercholesterolemia (FH) are two genetic disorders giving rise to severe disturbances of lipid homeostasis and premature atherosclerosis."1.33Effects of fenofibrate on apolipoprotein kinetics in patients with coexisting dysbetalipoproteinemia and heterozygous familial hypercholesterolemia. ( Couture, P; Deshaies, Y; Gagné, C; Hogue, JC; Lamarche, B; Ruel, IL; Tremblay, AJ, 2006)
"In patients with type IIa or IIb dyslipidemia, TC decreased (-14."1.31Efficacy and tolerability of a "suprabioavailable" formulation of fenofibrate in patients with dyslipidemia: a pooled analysis of two open-label trials. ( Callaghan, DJ; Ramjattan, BR; Theiss, U, 2002)
"Fibrinogen in plasma was reduced from 3."1.29[The effect of micronized fenofibrate on lipid parameters and fibrinogen in heterozygous familial hypercholesterolemia and familial combined hyperlipidemia]. ( Ceska, R; Haas, T; Kvasilová, M; Kvasnicka, J; Procházková, R; Sobra, J, 1996)
"Twenty two patients with primary type II hyperlipoproteinemia (13 phenotype IIa and 9 phenotype IIb) were treated with fenofibrate 300 mg a day for 4-12 months."1.27Long-term effects of fenofibrate on serum lipids and on lipoprotein cholesterol in type II hyperlipoproteinemic patients. ( Bonfiglioli, D; Cabrini, E; Fasoli, A; Pogliaghi, I; Sommariva, D, 1984)
"In patients with heterozygous familial hypercholesterolemia (FH), bezafibrate (n = 5) and fenofibrate (n = 7) produced a similar significant reduction of total cholesterol, LDL-cholesterol, and triglycerides by 21, 23, and 32%, respectively."1.27Biliary lipid secretion in patients with heterozygous familial hypercholesterolemia and combined hyperlipidemia. Influence of bezafibrate and fenofibrate. ( Leiss, O; Meyer-Krahmer, K; von Bergmann, K, 1986)
"Fenofibrate was well tolerated, both clinically and biologically."1.26[One year fenofibrate treatment of type II primary hyperlipidaemia. Effects on lipoproteins and biological tolerance (author's transl)]. ( Debry, G; Drouin, P; Lambert, D; Méjean, L; Wülfert, E, 1980)
"Fenofibrate was well tolerated."1.26[Effects of fenofibrate in four types of hyperlipoproteinaemia and on apoproteins A and B in type IIa HLP (author's transl)]. ( Gustafson, A; Micheli, H; Pometta, D, 1980)
"Fenofibrate was also found to normalize platelet aggregation in patients with type IIb HLP."1.26[Pharmacology of fenofibrate (author's transl)]. ( Kritchevsky, D, 1980)
"Eleven patients with hyperlipoproteinemia (HLP) type II A, were treated for 3 months with a new compound, a phenoxy-isobuturic acid derivative, procetofen, at a dosage of 100 mg t."1.26Treatment of hyperlipoproteinemia (HLP) type II A with a new phenoxy-isobuturic acid derivative, procetofen. ( Gustafson, A; Micheli, H; Pometta, D, 1979)

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-199043 (59.72)18.7374
1990's19 (26.39)18.2507
2000's9 (12.50)29.6817
2010's1 (1.39)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Page, MM1
Ekinci, EI1
Jones, RM1
Angus, PW1
Gow, PJ1
O'Brien, RC1
Ansquer, JC1
Bekaert, I1
Guy, M1
Hanefeld, M1
Simon, A1
Ramjattan, BR1
Callaghan, DJ1
Theiss, U1
Okopień, B5
Cwalina, Ł1
Haberka, M1
Kowalski, J5
Zieliński, M5
Szwed, Z1
Kalina, Z5
Herman, ZS4
Madej, A3
Belowski, D1
Paragh, G1
Seres, I1
Harangi, M1
Balogh, Z1
Illyés, L1
Boda, J1
Szilvássy, Z1
Kovács, P1
Tremblay, AJ1
Lamarche, B1
Ruel, IL1
Hogue, JC1
Deshaies, Y1
Gagné, C1
Couture, P1
Christidis, DS1
Liberopoulos, EN1
Kakafika, AI1
Miltiadous, GA1
Cariolou, M1
Ganotakis, ES1
Mikhailidis, DP1
Elisaf, MS1
Kourimate, S1
Le May, C1
Langhi, C1
Jarnoux, AL1
Ouguerram, K1
Zaïr, Y1
Nguyen, P1
Krempf, M1
Cariou, B1
Costet, P1
Paoletti, R1
Franceschini, G2
Sirtori, CR2
Sznajd, J1
Magdoń, M1
Idzior, B1
Konarska, R1
Malczewska, M1
Czarnecka, H1
Sznajderman, M2
Sommariva, D3
Bonfiglioli, D2
Pogliaghi, I2
Ottomano, C1
Fasoli, A3
Cabrini, E1
Capurso, A1
Mogavero, AM1
Taverniti, R1
Resta, F1
Pace, L1
Bonomo, L1
Chicaud, P1
Demange, J1
Drouin, P7
Debry, G6
Gariot, P2
Barrat, E2
Mejean, L3
Pointel, JP2
Schwartzkopff, W2
Luley, C2
Scheffler, W2
Lehmann-Leo, W1
Schilling, A2
Wegscheider, K1
Lehtonen, A1
Viikari, J1
Lambert, D2
Wülfert, E1
Micheli, H2
Pometta, D2
Gustafson, A2
Renaud, S2
Dumont, E2
Kritchevsky, D1
Ducobu, J1
Calder, D1
Canzler, H1
Bojanovski, D1
Brousseau, T1
Lecerf, JM1
Luc, G1
Devulder, B1
Fruchart, JC2
Amouyel, P1
Kornitzer, M1
Dramaix, M1
Vandenbroek, MD1
Everaert, L1
Gerlinger, C1
Shepherd, J1
Föger, B1
Drexel, H1
Hopferwieser, T1
Miesenböck, G1
Ritsch, A1
Lechleitner, M1
Tröbinger, G1
Patsch, JR1
Branchi, A1
Rovellini, A1
Gugliandolo, AG1
Chojnowska-Jezierska, J1
Jabłoński, S1
Tkaczewski, W1
Bruckert, E1
De Gennes, JL1
Malbecq, W1
Baigts, F1
Steinmetz, A1
Schwartz, T1
Hehnke, U1
Kaffarnik, H1
Ceska, R1
Sobra, J1
Kvasnicka, J1
Procházková, R1
Kvasilová, M1
Haas, T1
Farmer, JA1
Gotto, AM1
Raslová, K1
Dubovská, D1
Mongiellová, V1
Trnovec, T1
Wierzbicki, AS2
Lumb, PJ2
Cheung, J1
Crook, MA2
Wysocki, J2
Szygula, B1
Semra, YK1
Szyguła, B1
Herman, Z1
Bergemann, R1
Brandt, A1
Siegrist, W1
Kirchgässler, KU1
Schiffner-Rohe, J1
Stahlheber, U1
Cwalina, L1
Lebek, M1
Wisniewska-Wanat, M1
Morazain, R1
Sauvanet, JP2
Ol'binskaia, LI1
Vartanova, OA1
Aleksandrovskaia, TN1
Shaldaeva, VV1
Schlienger, JL1
Boucherle, A1
Calop, J1
Rossignol, AM1
Bost, M1
Weisweiler, P3
Schwandt, P2
Karádi, I1
Pados, G1
Németh-Csóka, M1
Romics, L1
Reiner, Z1
Salzer, B1
Kes, P1
Bard, JM1
Fievet, C1
Kandoussi, A1
Slimane, M1
Douste-Blazy, P1
Bertolini, S1
Elicio, N1
Daga, A1
Degl'Innocenti, ML1
Balestreri, R1
Fusi, MG1
Cotta Ramusino, AM1
Carozzi, A1
Hunninghake, DB1
Peters, JR1
Palmer, RH2
Knopp, RH1
Brown, WV2
Dujovne, CA1
Farquhar, JW1
Feldman, EB1
Goldberg, AC2
Grundy, SM1
Lasser, NL1
Mellies, MJ1
Schonfeld, G1
Anderson, C1
Dillingham, MA1
Jacotot, B1
Beaumont, JL1
Beaumont, V1
Buxtorf, JC1
Edouard, L1
Doucet, F1
Carcone, B1
Merk, W1
Jacob, B1
Baggio, G1
Gasparotto, A1
Ciuffetti, G1
Valerio, G1
Fellin, R1
Senin, U1
Gabelli, C1
Crepaldi, G1
Leiss, O1
Meyer-Krahmer, K1
von Bergmann, K1
Genton, P1
Foliguet, B1
Kolopp, M1
Malmendier, CL2
Delcroix, C2
Lontie, JF1
Postiglione, A1
Rubba, P1
Cicerano, U1
Chierchia, I1
Mancini, M1
Rouffy, J1
Chanu, B1
Bakir, R1
Djian, F1
Goy-Loeper, J1
Sirtori, M1
Gianfranceschi, G1
Frosi, T1
Montanari, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomised, Double-Blind Study Comparing the Efficacy and Safety of 145 mg Fenofibrate, 10 mg Ezetimibe and Their Combination in Patients With Type IIb Dyslipidemia and Features of the Metabolic Syndrome[NCT00349284]Phase 3181 participants Interventional2005-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for fenofibrate and Apolipoprotein B-100, Familial Defective

ArticleYear
Liver transplantation for the treatment of homozygous familial hypercholesterolaemia in an era of emerging lipid-lowering therapies.
    Internal medicine journal, 2014, Volume: 44, Issue:6

    Topics: Adult; Atorvastatin; Azetidines; Blood Component Removal; Cholesterol, LDL; Combined Modality Therap

2014
The fibrates in clinical practice: focus on micronised fenofibrate.
    Atherosclerosis, 1994, Volume: 110 Suppl

    Topics: Adolescent; Adult; Aged; Cholesterol, LDL; Coronary Disease; Drug Compounding; Female; Fenofibrate;

1994
Choosing the right lipid-regulating agent. A guide to selection.
    Drugs, 1996, Volume: 52, Issue:5

    Topics: Anticholesteremic Agents; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Colestipol; Fenofibrat

1996
Effect of fibric acid derivatives on blood lipid and lipoprotein levels.
    The American journal of medicine, 1987, Nov-27, Volume: 83, Issue:5B

    Topics: Anticholesteremic Agents; Bezafibrate; Clofibrate; Clofibric Acid; Fenofibrate; Fibric Acids; Gemfib

1987
Effects of fibric acid derivatives on biliary lipid composition.
    The American journal of medicine, 1987, Nov-27, Volume: 83, Issue:5B

    Topics: Bezafibrate; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Feno

1987

Trials

25 trials available for fenofibrate and Apolipoprotein B-100, Familial Defective

ArticleYear
Efficacy and safety of coadministration of fenofibrate and ezetimibe compared with each as monotherapy in patients with type IIb dyslipidemia and features of the metabolic syndrome: a prospective, randomized, double-blind, three-parallel arm, multicenter,
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2009, Volume: 9, Issue:2

    Topics: Anticholesteremic Agents; Azetidines; Double-Blind Method; Drug Therapy, Combination; Ezetimibe; Fem

2009
Influence of bezafibrate, fenofibrate, nicotinic acid and etofibrate on plasma high-density lipoprotein levels.
    The American journal of cardiology, 1983, Aug-22, Volume: 52, Issue:4

    Topics: Adipose Tissue; Animals; Apolipoprotein C-II; Apolipoprotein C-III; Apolipoproteins; Apolipoproteins

1983
[Effect of lipanthyl on parameters of lipid metabolism in patients with primary hyperlipoproteinemia].
    Przeglad lekarski, 1984, Volume: 41, Issue:2

    Topics: Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Double-Blind Method; Female; Fenofibrate; H

1984
[Comparison of the hypolipemic effects of bezafibrate and fenofibrate in patients with hyperlipoproteinemia type II and IV].
    Przeglad lekarski, 1984, Volume: 41, Issue:7

    Topics: Adult; Aged; Bezafibrate; Cholesterol; Clinical Trials as Topic; Female; Fenofibrate; Humans; Hyperl

1984
[Efficacy of bezafibrate and fenofibrate on elevated blood lipids in HLP type IIa, IIb and IV].
    Die Medizinische Welt, 1982, Apr-30, Volume: 33, Issue:17

    Topics: Adult; Aged; Anticholesteremic Agents; Bezafibrate; Clofibrate; Clofibric Acid; Female; Fenofibrate;

1982
Lowering effect of fenofibrate (procetofene) on lipoproteins in different types of hyperlipoproteinemias.
    Artery, 1980, Volume: 8, Issue:2

    Topics: Cholesterol; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type II

1980
Efficacy and tolerance of 200 mg micronised fenofibrate administered over a 6-month period in hyperlipidaemic patients: an open Belgian multicenter study.
    Atherosclerosis, 1994, Volume: 110 Suppl

    Topics: Adolescent; Adult; Aged; Belgium; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Drug Compounding;

1994
Fenofibrate improves postprandial chylomicron clearance in II B hyperlipoproteinemia.
    The Clinical investigator, 1994, Volume: 72, Issue:4

    Topics: Adult; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cholesterol Esters; Chylomicrons; Diet

1994
Comparison of the efficacy of simvastatin and standard fibrate therapy in the treatment of primary hypercholesterolemia and combined hyperlipidemia.
    Clinical cardiology, 1995, Volume: 18, Issue:11

    Topics: Anticholesteremic Agents; Bezafibrate; Cholesterol, LDL; Clofibric Acid; Fatty Acids, Volatile; Fema

1995
Multicenter comparison of micronized fenofibrate and simvastatin in patients with primary type IIA or IIB hyperlipoproteinemia.
    Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Cholesterol, HDL; Cholesterol, LDL; Female; Fenof

1996
Relationship between plasma fenofibric acid levels and the effect of micronized fenofibrate on cholesterol, low-density-lipoprotein cholesterol and apolipoprotein B in patients with primary hypercholesterolemia.
    European journal of clinical pharmacology, 1997, Volume: 52, Issue:2

    Topics: Adult; Anticholesteremic Agents; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Drug Administrati

1997
Fenofibrate plus simvastatin therapy versus simvastatin plus cholestyramine therapy for familial hypercholesterolaemia.
    QJM : monthly journal of the Association of Physicians, 1997, Volume: 90, Issue:10

    Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Cholestero

1997
Effects of fenofibrate on plasma cytokine concentrations in patients with atherosclerosis and hyperlipoproteinemia IIb.
    International journal of clinical pharmacology and therapeutics, 1998, Volume: 36, Issue:6

    Topics: Adult; Arteriosclerosis; Cytokines; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hypol

1998
High-dose atorvastatin therapy in severe heterozygous familial hypercholesterolaemia.
    QJM : monthly journal of the Association of Physicians, 1998, Volume: 91, Issue:4

    Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Atorvastatin; Cholesterol; Cholesterol, HDL; Chol

1998
[Levels of tumor necrosis factor alpha in serum of patients with hyperlipoproteinemia IIB before and after micronized fenofibrate therapy].
    Polskie Archiwum Medycyny Wewnetrznej, 1998, Volume: 99, Issue:4

    Topics: Adult; Apolipoproteins B; Arteriosclerosis; Cholesterol; Drug Compounding; Female; Fenofibrate; Huma

1998
Cost effectiveness of micronised fenofibrate and simvastatin in the short-term treatment of type IIa and type IIb hyperlipidaemia.
    PharmacoEconomics, 1997, Volume: 12, Issue:2 Pt 2

    Topics: Anticholesteremic Agents; Double-Blind Method; Female; Fenofibrate; Humans; Hyperlipoproteinemia Typ

1997
Effects of fibrates on plasma prothrombotic activity in patients with type IIb dyslipidemia.
    International journal of clinical pharmacology and therapeutics, 2001, Volume: 39, Issue:12

    Topics: Adult; Cholesterol, HDL; Cholesterol, LDL; Clofibric Acid; Female; Fenofibrate; Fibric Acids; Fibrin

2001
Low-dose colestipol plus fenofibrate: effects on plasma lipoproteins, lecithin:cholesterol acyltransferase, and postheparin lipases in familial hypercholesterolemia.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:3

    Topics: Adolescent; Adult; Apolipoproteins; Cholesterol, HDL; Cholesterol, LDL; Colestipol; Drug Therapy, Co

1989
Effect of a single daily dose treatment of fenofibrate on plasma lipoproteins in hyperlipoproteinaemia IIb.
    European journal of clinical pharmacology, 1988, Volume: 34, Issue:1

    Topics: Adult; Anticholesteremic Agents; Capsules; Clinical Trials as Topic; Drug Administration Schedule; F

1988
Effects of fibric acid derivatives on biliary lipid composition.
    The American journal of medicine, 1987, Nov-27, Volume: 83, Issue:5B

    Topics: Bezafibrate; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Feno

1987
Effects of fenofibrate on plasma lipoproteins in hypercholesterolemia and combined hyperlipidemia.
    The American journal of medicine, 1987, Nov-27, Volume: 83, Issue:5B

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Fenofibrate; Humans; Hyperlipide

1987
Fenofibrate affects the compositions of lipoproteins.
    The American journal of medicine, 1987, Nov-27, Volume: 83, Issue:5B

    Topics: Adult; Apolipoproteins; Cholesterol; Clinical Trials as Topic; Double-Blind Method; Female; Fenofibr

1987
Effects of several lipid-lowering drugs on skin total and esterified cholesterol.
    Monographs on atherosclerosis, 1986, Volume: 14

    Topics: Cholesterol Esters; Clinical Trials as Topic; Clofibric Acid; Fenofibrate; Fibric Acids; Humans; Hyp

1986
Pantethine versus fenofibrate in the treatment of type II hyperlipoproteinemia.
    Monographs on atherosclerosis, 1985, Volume: 13

    Topics: Clinical Trials as Topic; Double-Blind Method; Female; Fenofibrate; Humans; Hyperlipoproteinemia Typ

1985
Comparative evaluation of the effects of ciprofibrate and fenofibrate on lipids, lipoproteins and apoproteins A and B.
    Atherosclerosis, 1985, Volume: 54, Issue:3

    Topics: Adult; Apolipoproteins A; Apolipoproteins B; Clofibrate; Clofibric Acid; Drug Evaluation; Female; Fe

1985

Other Studies

43 other studies available for fenofibrate and Apolipoprotein B-100, Familial Defective

ArticleYear
Efficacy and tolerability of a "suprabioavailable" formulation of fenofibrate in patients with dyslipidemia: a pooled analysis of two open-label trials.
    Clinical therapeutics, 2002, Volume: 24, Issue:7

    Topics: Adolescent; Adult; Aged; Biological Availability; Cholesterol, HDL; Clinical Trials as Topic; Female

2002
[Pleiotropic effects of micronized fenofibrate in patients with combined hyperlipidemia].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2002, Volume: 13, Issue:78

    Topics: Adult; Carrier Proteins; Cholesterol, HDL; Cholesterol, LDL; Cytokines; Enzyme-Linked Immunosorbent

2002
Effects of fenofibrate and simvastatin on plasma sICAM-1 and MCP-1 concentrations in patients with hyperlipoproteinemia.
    International journal of clinical pharmacology and therapeutics, 2003, Volume: 41, Issue:6

    Topics: Chemokine CCL2; Enzyme-Linked Immunosorbent Assay; Female; Fenofibrate; Humans; Hyperlipoproteinemia

2003
The effect of micronised fenofibrate on paraoxonase activity in patients with coronary heart disease.
    Diabetes & metabolism, 2003, Volume: 29, Issue:6

    Topics: Adult; Antioxidants; Apolipoprotein A-I; Apolipoproteins B; Aryldialkylphosphatase; Body Mass Index;

2003
Effects of fenofibrate on apolipoprotein kinetics in patients with coexisting dysbetalipoproteinemia and heterozygous familial hypercholesterolemia.
    Atherosclerosis, 2006, Volume: 188, Issue:1

    Topics: Adult; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoprotein B-48; Apolipoproteins; Fenofibrate;

2006
The effect of apolipoprotein E polymorphism on the response to lipid-lowering treatment with atorvastatin or fenofibrate.
    Journal of cardiovascular pharmacology and therapeutics, 2006, Volume: 11, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Apolipoprotein A-I; Apolipoproteins B; Apolipoproteins E; Atorvas

2006
Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9.
    The Journal of biological chemistry, 2008, Apr-11, Volume: 283, Issue:15

    Topics: Anticholesteremic Agents; Cell Line, Tumor; Clofibric Acid; DNA-Binding Proteins; Fenofibrate; Furin

2008
Fenofibrate therapy of hypertriglyceridaemia. Differential effects on LDL cholesterol level in type IV and in type IIb primary hyperlipoproteinaemia.
    European journal of clinical pharmacology, 1984, Volume: 26, Issue:6

    Topics: Adult; Cholesterol, HDL; Cholesterol, LDL; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperl

1984
Long-term effects of fenofibrate on serum lipids and on lipoprotein cholesterol in type II hyperlipoproteinemic patients.
    Pharmacological research communications, 1984, Volume: 16, Issue:8

    Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Female; Fenofibrate

1984
Effect of procetofen on serum lipids and apoproteins.
    International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:4

    Topics: Adult; Apoproteins; Cholesterol; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Lipids;

1984
Application of the concanavalin A precipitation technique in an evaluation of fenofibrate action on cholesterolemia in IIa and IIb hyperlipemic subjects.
    Pharmacology, 1983, Volume: 26, Issue:2

    Topics: Adult; Aged; Aging; Anticholesteremic Agents; Chemical Precipitation; Cholesterol; Concanavalin A; F

1983
Fenofibrate and human liver. Lack of proliferation of peroxisomes.
    Archives of toxicology, 1983, Volume: 53, Issue:2

    Topics: Adult; Aged; Cell Division; Diet; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperli

1983
Fenofibrate and cholestyramine in type II hyperlipoproteinaemia.
    Artery, 1982, Volume: 10, Issue:5

    Topics: Adult; Aspartate Aminotransferases; Cholesterol; Cholestyramine Resin; Fenofibrate; Humans; Hyperlip

1982
[One year fenofibrate treatment of type II primary hyperlipidaemia. Effects on lipoproteins and biological tolerance (author's transl)].
    La Nouvelle presse medicale, 1980, Dec-22, Volume: 9, Issue:49

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Cholesterol; Dietary Fats; Female; Fenofibrate; Human

1980
[Effects of fenofibrate in four types of hyperlipoproteinaemia and on apoproteins A and B in type IIa HLP (author's transl)].
    La Nouvelle presse medicale, 1980, Dec-22, Volume: 9, Issue:49

    Topics: Apolipoproteins; Apolipoproteins A; Apolipoproteins B; Cholesterol; Female; Fenofibrate; Humans; Hyp

1980
[Influence of fenofibrate on blood platelet functions (author's transl)].
    La Nouvelle presse medicale, 1980, Dec-22, Volume: 9, Issue:49

    Topics: Blood Coagulation; Cholesterol; Dietary Fats; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyp

1980
[Pharmacology of fenofibrate (author's transl)].
    La Nouvelle presse medicale, 1980, Dec-22, Volume: 9, Issue:49

    Topics: Animals; Cholesterol; Clofibrate; Dogs; Dose-Response Relationship, Drug; Fenofibrate; Humans; Hyper

1980
[Effect of phenofibrate on the blood serum lipid level in hyperlipoproteinemias and its comparison with clofibrate].
    Polskie Archiwum Medycyny Wewnetrznej, 1980, Volume: 63, Issue:6

    Topics: Adult; Aged; Cholesterol; Clofibrate; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyp

1980
[Clinical study of fenofibrate in hyperlipoproteinemias].
    Acta clinica Belgica, 1980, Volume: 35, Issue:3

    Topics: Adult; Aged; Cholesterol; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperlipoprotei

1980
The effect of etofibrate retard, bezafibrate and procetofen.
    Artery, 1980, Volume: 8, Issue:2

    Topics: Aged; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Female; Fenofibrate; Humans; Hyperlipopr

1980
[Detection of the Arg 3500-->Gln mutation of B apolipoprotein. Value in clinical practice].
    Presse medicale (Paris, France : 1983), 1995, Apr-29, Volume: 24, Issue:16

    Topics: Adult; Anticholesteremic Agents; Apolipoprotein B-100; Apolipoproteins B; Cholesterol; Cholesterol,

1995
Effect of three fibrate derivatives and of two HMG-CoA reductase inhibitors on plasma fibrinogen level in patients with primary hypercholesterolemia.
    Thrombosis and haemostasis, 1993, Aug-02, Volume: 70, Issue:2

    Topics: Adult; Aged; Bezafibrate; Cholesterol, Dietary; Combined Modality Therapy; Female; Fenofibrate; Fibr

1993
[Clinical effectiveness of acipimox and fenofibrate in patients with hyperlipoproteinemia type II].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1993, Volume: 46, Issue:9-10

    Topics: Adult; Aged; Cholesterol; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hypolipidemic A

1993
[The effect of micronized fenofibrate on lipid parameters and fibrinogen in heterozygous familial hypercholesterolemia and familial combined hyperlipidemia].
    Casopis lekaru ceskych, 1996, Jul-26, Volume: 135, Issue:13

    Topics: Adult; Aged; Female; Fenofibrate; Fibrinogen; Heterozygote; Humans; Hyperlipidemia, Familial Combine

1996
Cost-effectiveness study of a lipid-lowering therapy in hyperlipoproteinaemia type IIb and type IV (Frederickson).
    PharmacoEconomics, 1993, Volume: 3, Issue:2

    Topics: Bezafibrate; Cost-Benefit Analysis; Diabetes Complications; Fenofibrate; Gemfibrozil; Humans; Hyperl

1993
Influence of a hypolipemic drug (procetofene) on platelet functions and lipid composition in type II B hyperlipoproteinemia.
    Haemostasis, 1979, Volume: 8, Issue:2

    Topics: Adenosine Diphosphate; Adult; Blood Coagulation; Cholesterol; Epinephrine; Fenofibrate; Humans; Hype

1979
Treatment of hyperlipoproteinemia (HLP) type II A with a new phenoxy-isobuturic acid derivative, procetofen.
    International journal of clinical pharmacology and biopharmacy, 1979, Volume: 17, Issue:12

    Topics: Adult; Aged; Apolipoproteins; Body Weight; Cholesterol; Female; Fenofibrate; Humans; Hyperlipoprotei

1979
[Effect of procetofen on the lipoprotein profile in patients with type II hyperlipoproteinemia].
    Die Medizinische Welt, 1979, Dec-14, Volume: 30, Issue:50

    Topics: Adult; Aged; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Lipoproteins; Male; Middle A

1979
[The clinico-biochemical activity and tolerance of the hypolipidemic preparation lipanthyl].
    Terapevticheskii arkhiv, 1991, Volume: 63, Issue:8

    Topics: Arteriosclerosis; Drug Evaluation; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperl

1991
[Evaluation of the addition of fenofibrate to the simvastatin-cholestyramine combination].
    Presse medicale (Paris, France : 1983), 1991, Mar-30, Volume: 20, Issue:12

    Topics: Anticholesteremic Agents; Cholestyramine Resin; Drug Therapy, Combination; Fenofibrate; Humans; Hype

1991
[Treatment of essential hypercholesterolemia by normolipidemic drugs in children].
    Pediatrie, 1989, Volume: 44, Issue:8

    Topics: Adolescent; Child; Child, Preschool; Cholestyramine Resin; Clofibrate; Fenofibrate; Humans; Hydroxym

1989
Colestipol plus fenofibrate versus synvinolin in familial hypercholesterolaemia.
    Lancet (London, England), 1986, Nov-22, Volume: 2, Issue:8517

    Topics: Adult; Cholesterol, LDL; Colestipol; Drug Therapy, Combination; Fenofibrate; Humans; Hyperlipoprotei

1986
[The effect of lipanthyl therapy on hyperlipoproteinemia type II/a, II/b and IV].
    Orvosi hetilap, 1988, Aug-14, Volume: 129, Issue:33

    Topics: Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Propionates

1988
[Comparison of the effects of fenofibrate administered in doses of 3 x 100mg and 1 x 250mg per day in patients with type IIA, IIB and IV hyperlipoproteinemias].
    Acta medica Iugoslavica, 1988, Volume: 42, Issue:5

    Topics: Adult; Aged; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV

1988
Effect of fenofibrate on apolipoprotein B containing lipoprotein particles.
    Progress in clinical and biological research, 1988, Volume: 255

    Topics: Apolipoproteins B; Double-Blind Method; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; H

1988
Potential use of fenofibrate and other fibric acid derivatives in the clinic.
    The American journal of medicine, 1987, Nov-27, Volume: 83, Issue:5B

    Topics: Clofibrate; Fenofibrate; Humans; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Hy

1987
Fenofibrate and colestipol: effects on serum and lipoprotein lipids and apolipoproteins in familial hypercholesterolaemia.
    European journal of clinical pharmacology, 1986, Volume: 30, Issue:2

    Topics: Adult; Apolipoproteins; Body Weight; Cholesterol; Cholesterol, HDL; Colestipol; Female; Fenofibrate;

1986
Long term-effect of fenofibrate on lipoprotein level and composition in different types of genetic hyperlipidemias.
    Pharmacological research communications, 1986, Volume: 18, Issue:5

    Topics: Cholesterol; Cholesterol, LDL; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperlipop

1986
Biliary lipid secretion in patients with heterozygous familial hypercholesterolemia and combined hyperlipidemia. Influence of bezafibrate and fenofibrate.
    Journal of lipid research, 1986, Volume: 27, Issue:7

    Topics: Adult; Bezafibrate; Bile; Bile Acids and Salts; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Fem

1986
Morphometric study of human hepatic cell modifications induced by fenofibrate.
    Metabolism: clinical and experimental, 1987, Volume: 36, Issue:3

    Topics: Adult; Aged; Female; Fenofibrate; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type V;

1987
The effect of combined fenofibrate and cholestyramine therapy on low-density lipoprotein kinetics in familial hypercholesterolemia patients.
    Clinica chimica acta; international journal of clinical chemistry, 1987, Jan-30, Volume: 162, Issue:2

    Topics: Adult; Apolipoproteins; Cholestyramine Resin; Drug Therapy, Combination; Female; Fenofibrate; Humans

1987
Effects of fenofibrate on high and low density lipoprotein metabolism in heterozygous familial hypercholesterolemia.
    Atherosclerosis, 1985, Volume: 55, Issue:2

    Topics: Adult; Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins B; Female; Fenofibrate; Humans; Hyperl

1985
Reversible increase of the apo CII/apo CIII-1 ratio in the very low density lipoproteins after procetofen treatment in hypertriglyceridemic patients.
    Artery, 1985, Volume: 12, Issue:6

    Topics: Adult; Aged; Apolipoprotein C-II; Apolipoprotein C-III; Apolipoproteins C; Cholesterol, HDL; Cholest

1985