fenofibrate has been researched along with Aortic Valve Insufficiency in 2 studies
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Aortic Valve Insufficiency: Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with fenofibrate, a PPARα agonist, normalized both FA and glucose uptake while reducing LV dilation caused by AR." | 1.42 | Transcriptional Changes Associated with Long-Term Left Ventricle Volume Overload in Rats: Impact on Enzymes Related to Myocardial Energy Metabolism. ( Arsenault, M; Couet, J; Dhahri, W; Drolet, MC; Gascon, S; Lachance, D; Lecomte, R; Rousseau, JA; Roussel, E; Sarrhini, O; Walsh-Wilkinson, E, 2015) |
| "Fenofibrate is a peroxisome proliferator-associated receptor alpha agonist (PPARα) used clinically for the management of dyslipidemia and is a myocardial fatty acid oxidation stimulator." | 1.39 | Fenofibrate reduces cardiac remodeling and improves cardiac function in a rat model of severe left ventricle volume overload. ( Arsenault, M; Couet, J; Dhahri, W; Drolet, MC; Roussel, É, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roussel, E | 2 |
| Drolet, MC | 2 |
| Walsh-Wilkinson, E | 1 |
| Dhahri, W | 2 |
| Lachance, D | 1 |
| Gascon, S | 1 |
| Sarrhini, O | 1 |
| Rousseau, JA | 1 |
| Lecomte, R | 1 |
| Couet, J | 2 |
| Arsenault, M | 2 |
2 other studies available for fenofibrate and Aortic Valve Insufficiency
| Article | Year |
|---|---|
Transcriptional Changes Associated with Long-Term Left Ventricle Volume Overload in Rats: Impact on Enzymes Related to Myocardial Energy Metabolism.
Topics: Animals; Aortic Valve Insufficiency; Cardiac Volume; Disease Models, Animal; Energy Metabolism; Feno | 2015 |
Fenofibrate reduces cardiac remodeling and improves cardiac function in a rat model of severe left ventricle volume overload.
Topics: Animals; Aortic Valve Insufficiency; Disease Models, Animal; Fatty Acids; Fenofibrate; Hypolipidemic | 2013 |