fenofibrate has been researched along with Amyotrophic Lateral Sclerosis in 1 studies
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Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Esmaeili, MA | 1 |
| Yadav, S | 1 |
| Gupta, RK | 1 |
| Waggoner, GR | 1 |
| Deloach, A | 1 |
| Calingasan, NY | 1 |
| Beal, MF | 1 |
| Kiaei, M | 1 |
1 other study available for fenofibrate and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegeneration in vivo.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Death; Disease Models, Animal; Disease Progression; Fem | 2016 |