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fenofibrate and Amyloidosis

fenofibrate has been researched along with Amyloidosis in 3 studies

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Amyloidosis: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.

Research Excerpts

ExcerptRelevanceReference
"To examine the effects of the lipid-lowering agent fenofibrate on experimental AA amyloidosis and on serum amyloid A (SAA) levels."7.71Fenofibrate inhibits reactive amyloidosis in mice. ( Arai, K; Endo, N; Hanyu, T; Miida, T; Murai, T; Yamada, T, 2002)
"Flurbiprofen (1) analogues were obtained with enhanced anti-inflammatory and antiamyloidogenic properties compared to 1, however, esterification led to elevated Aβ(1-42) levels."1.37Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates. ( Abdul-Hay, S; Qin, Z; Schiefer, IT; Thatcher, GR; Vanni, M; Wang, H, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schiefer, IT1
Abdul-Hay, S1
Wang, H1
Vanni, M1
Qin, Z1
Thatcher, GR1
Zhang, H1
Gao, Y1
Qiao, PF1
Zhao, FL1
Yan, Y1
Murai, T1
Yamada, T1
Miida, T1
Arai, K1
Endo, N1
Hanyu, T1

Other Studies

3 other studies available for fenofibrate and Amyloidosis

ArticleYear
Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates.
    Journal of medicinal chemistry, 2011, Apr-14, Volume: 54, Issue:7

    Topics: Amyloid beta-Peptides; Amyloidosis; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non

2011
Fenofibrate reduces amyloidogenic processing of APP in APP/PS1 transgenic mice via PPAR-α/PI3-K pathway.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2014, Volume: 38

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Amyloid

2014
Fenofibrate inhibits reactive amyloidosis in mice.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:6

    Topics: Acute-Phase Proteins; Amyloidosis; Animals; Female; Fenofibrate; Hypolipidemic Agents; Interleukin-6

2002