fenofibrate has been researched along with Adrenoleukodystrophy in 3 studies
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Adrenoleukodystrophy: An X-linked recessive disorder characterized by the accumulation of saturated very long chain fatty acids in the LYSOSOMES of ADRENAL CORTEX and the white matter of CENTRAL NERVOUS SYSTEM. This disease occurs almost exclusively in the males. Clinical features include the childhood onset of ATAXIA; NEUROBEHAVIORAL MANIFESTATIONS; HYPERPIGMENTATION; ADRENAL INSUFFICIENCY; SEIZURES; MUSCLE SPASTICITY; and DEMENTIA. The slowly progressive adult form is called adrenomyeloneuropathy. The defective gene ABCD1 is located at Xq28, and encodes the adrenoleukodystrophy protein (ATP-BINDING CASSETTE TRANSPORTERS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fenofibrate, which is a potent inducer of the ALDR gene in the liver of adult rats, could not induce the ALDR gene in suckling rats." | 1.31 | Rat adrenoleukodystrophy-related (ALDR) gene: full-length cDNA sequence and new insight in expression. ( Albet, S; Bentejac, M; Berger, J; Bugaut, M; Gondcaille, C; Netik, A; Savary, S; Szpirer, C; Troffer-Charlier, N, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Netik, A | 2 |
| Forss-Petter, S | 1 |
| Holzinger, A | 2 |
| Molzer, B | 1 |
| Unterrainer, G | 1 |
| Berger, J | 3 |
| Albet, S | 2 |
| Bentejac, M | 2 |
| Savary, S | 2 |
| Gondcaille, C | 2 |
| Szpirer, C | 1 |
| Troffer-Charlier, N | 1 |
| Bugaut, M | 2 |
| Fourcade, S | 1 |
| Gauthé, D | 1 |
| Pineau, T | 1 |
| Bellenger, J | 1 |
3 other studies available for fenofibrate and Adrenoleukodystrophy
| Article | Year |
|---|---|
Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy.
Topics: Adrenoleukodystrophy; Animals; ATP Binding Cassette Transporter, Subfamily D; ATP Binding Cassette T | 1999 |
Rat adrenoleukodystrophy-related (ALDR) gene: full-length cDNA sequence and new insight in expression.
Topics: 3' Untranslated Regions; 5' Untranslated Regions; Adrenoleukodystrophy; Amino Acid Sequence; Animals | 2001 |
Fibrate induction of the adrenoleukodystrophy-related gene (ABCD2): promoter analysis and role of the peroxisome proliferator-activated receptor PPARalpha.
Topics: Adrenoleukodystrophy; Animals; ATP Binding Cassette Transporter, Subfamily D; ATP-Binding Cassette T | 2001 |