fenfluramine has been researched along with Deficiency Diseases in 1 studies
Fenfluramine: A centrally active drug that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release.
fenfluramine : A secondary amino compound that is 1-phenyl-propan-2-amine in which one of the meta-hydrogens is substituted by trifluoromethyl, and one of the hydrogens attached to the nitrogen is substituted by an ethyl group. It binds to the serotonin reuptake pump, causing inhbition of serotonin uptake and release of serotonin. The resulting increased levels of serotonin lead to greater serotonin receptor activation which in turn lead to enhancement of serotoninergic transmission in the centres of feeding behavior located in the hypothalamus. This suppresses the appetite for carbohydrates. Fenfluramine was used as the hydrochloride for treatment of diabetes and obesity. It was withdrawn worldwide after reports of heart valve disease and pulmonary hypertension.
Deficiency Diseases: A condition produced by dietary or metabolic deficiency. The term includes all diseases caused by an insufficient supply of essential nutrients, i.e., protein (or amino acids), vitamins, and minerals. It also includes an inadequacy of calories. (From Dorland, 27th ed; Stedman, 25th ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kodas, E | 1 |
| Galineau, L | 1 |
| Bodard, S | 1 |
| Vancassel, S | 1 |
| Guilloteau, D | 1 |
| Besnard, JC | 1 |
| Chalon, S | 1 |
1 other study available for fenfluramine and Deficiency Diseases
| Article | Year |
|---|---|
Serotoninergic neurotransmission is affected by n-3 polyunsaturated fatty acids in the rat.
Topics: Age Factors; alpha-Linolenic Acid; Animals; Chronic Disease; Deficiency Diseases; Fatty Acids; Fatty | 2004 |