fenclonine has been researched along with Spasms, Infantile in 1 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Spasms, Infantile: An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Infantile spasms are characterized by age-specific expression of epileptic spasms and hypsarrhythmia and often result in significant cognitive impairment." | 1.36 | A model of symptomatic infantile spasms syndrome. ( Betancourth, D; Chudomelova, L; Galanopoulou, AS; Moshé, SL; Raffo, E; Scantlebury, MH, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scantlebury, MH | 1 |
| Galanopoulou, AS | 1 |
| Chudomelova, L | 1 |
| Raffo, E | 1 |
| Betancourth, D | 1 |
| Moshé, SL | 1 |
1 other study available for fenclonine and Spasms, Infantile
| Article | Year |
|---|---|
A model of symptomatic infantile spasms syndrome.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Antibiotics, Antineoplastic; Anticonvulsants | 2010 |