fenclonine has been researched along with Sleep Wake Disorders in 2 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "(4) the mechanisms of this hypersomnia are discussed in light of the biochemical results showing an increase of the biosynthesis of serotonin in the rostral raphe system." | 1.25 | [Hypersomnia by isthmic lesion in cat. II. Neurophysiological and pharmacological study]. ( Blondaux, C; Jouvet, M; Petitjean, F; Sakai, K, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Utsu, Y | 1 |
| Shinomiya, K | 1 |
| Tokunaga, S | 1 |
| Ohmori, A | 1 |
| Kamei, C | 1 |
| Petitjean, F | 1 |
| Sakai, K | 1 |
| Blondaux, C | 1 |
| Jouvet, M | 1 |
2 other studies available for fenclonine and Sleep Wake Disorders
| Article | Year |
|---|---|
Effect of tandospirone on sleep latency in rats placed on a grid suspended over water.
Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Anxiety Agents; Disease Models, Animal; Do | 2007 |
[Hypersomnia by isthmic lesion in cat. II. Neurophysiological and pharmacological study].
Topics: Animals; Cats; Disorders of Excessive Somnolence; Electroencephalography; Female; Fenclonine; Functi | 1975 |