Page last updated: 2024-11-02

fenclonine and Pregnancy

fenclonine has been researched along with Pregnancy in 100 studies

Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"This work attempts to study the cerebral alterations in rat offspring of hyperphenylalaninemic mothers, as well as the possibility of preventing them by means of administration of dietetic supplements of valine, leucine and isoleucine during the pregnancy."3.70[An experimental study on the effects of maternal hyperphenylalaninemia on the central nervous system and behavior of offspring rats]. ( Baldellou Vázquez, A; García Vera, C; Gracia Romero, J; Pérez-González, J; Ventura Faci, P, 1998)
" Moreover, there was no correlation between fetal phenylalanine blood levels and phenylalanine concentrations in amniotic fluid indicating that amniotic fluid phenylalanine levels would not be useful to monitor fetal phenylalanine blood concentrations during pregnancy."3.67Relationships among maternal and fetal amino acid blood concentrations and amniotic fluid amino acid levels in pregnant rhesus monkeys. ( Boylan, JM; Cha, CJ; Jackson, BT; Piasecki, GJ; Pueschel, SM, 1986)
"Infant rhesus monkeys were (a) fed a diet high in phenylalanine or (b) fed a diet high in p-chlorophenylalanine for the 1st 12 months of life, (c) selected from mothers fed a diet high in phenylalanine during pregnancy, (d) fed a diet low in phenylalanine, (e) maintained as controls, or (f) maintained as pair-fed controls."3.66Dietary and metabolic effects on rhesus social behavior: phenylalanine-related dietary alterations. ( Chamove, AS, 1980)
" Increased concentrations of phenylalanine and increased ratio of phenylalanine to tyrosine were demonstrated in blood from pregnant rats fed the experimental PKU diet from day 10 to 20 of pregnancy, in fetal blood and amniotic fluid of fetal animals from mothers fed the PKU diet, and in blood of rats fed the PKU diet for 28-30 days beginning at 20-21 days of age."3.65Biochemical effects of induced phenylketonuria in rats. ( Berry, HK; Butcher, RE; Kazmaier, KJ; Poncet, IB, 1975)
"Pretreatment with atropine (200 mg/kg body wt, sc) was effective to abolish this inhibitory effect of the HPC stimulation on the release of LH and FSH, whereas reserpine treatment (1mg/kg body wt, ip) did not affect the effect."1.26Cholinergic and serotonergic neural links and the inhibitory effects of hippocampus, lateral amygdala and central gray matter on gonadotropin release. ( Kawagoe, S; Kawakami, M; Kimura, F, 1976)
"Reserpine enhanced the incidence of seizures, and the effect was reversed by 5-hydroxytryptophan but not by dihydroxyphenylalanine."1.25Effects of aminergic drugs and glutamic acid on audiogenic seizures induced by early exposure to ethanol. ( Ginsburg, BE; Sze, PY; Yanai, J, 1975)

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-199074 (74.00)18.7374
1990's7 (7.00)18.2507
2000's15 (15.00)29.6817
2010's3 (3.00)24.3611
2020's1 (1.00)2.80

Authors

AuthorsStudies
Fabio, MC1
Servin-Bernal, IJC1
Degano, AL1
Pautassi, RM1
Goeden, N1
Velasquez, J1
Arnold, KA1
Chan, Y1
Lund, BT1
Anderson, GM1
Bonnin, A1
Vataeva, LA2
Kudrin, VS2
Vershinina, EA2
Mosin, VM2
Tiul'kova, EI2
Otellin, VA6
Chen, A1
Kelley, LD1
Janušonis, S1
Khozhaĭ, LI5
Pronina, T1
Ugrumov, M2
Adamskaya, E1
Kuznetsova, T1
Shishkina, I1
Babichev, V1
Calas, A3
Tramu, G1
Mailly, P1
Makarenko, I1
Mirochnik, VV1
Ugryumov, MV1
Bosler, O2
Butkevich, IP1
Mikhailenko, VA1
Rodriguez-Pallares, J1
Guerra, MJ1
Labandeira-Garcia, JL1
Matsuda, M1
Imaoka, T1
Vomachka, AJ1
Gudelsky, GA1
Hou, Z1
Mistry, M1
Bailey, JP1
Nieport, KM1
Walther, DJ1
Bader, M1
Horseman, ND1
Mirochnik, V1
Tillet, Y1
Vitalis, T1
Cases, O1
Passemard, S1
Callebert, J1
Parnavelas, JG1
Petrova, ES1
Loo, YH4
Fulton, T1
Miller, K1
Wisniewski, HM1
Walker, RF3
Meyerson, BJ2
Johnston, BM1
Walker, DW1
Green, AR1
Pueschel, SM4
Boylan, JM4
Jackson, BT4
Piasecki, GJ4
Marcó, J6
Rosero, O1
Villa, I2
Esquifino, A2
Larralde, J2
Moos, F1
Richard, P1
Leandro, V1
Lauder, JM5
Wallace, JA1
Wilkie, MB1
DiNome, A1
Krebs, H4
Cha, CJ2
Chamove, AS2
Cooper, RL1
Timiras, PS2
Coen, CW2
Franklin, M1
Laynes, RW1
MacKinnon, PC2
Fulton, TR1
Triano, T1
Rabe, A1
Vorhees, CV2
Butcher, RE2
Berry, HK3
Sapronova, AIa1
Adamskaia, EI1
Babichev, VN1
Proshliakova, EV1
Ugriumov, MV1
Gao, BX1
Ziskind-Conhaim, L1
García Vera, C1
Baldellou Vázquez, A1
Gracia Romero, J1
Ventura Faci, P1
Pérez-González, J1
Nakajima, K1
Matsuyama, K1
Mori, S1
Jahn, GA3
Kalia, V1
Hole, D1
Wilson, CA1
Deis, RP3
Banasr, M1
Hery, M2
Brezun, JM1
Daszuta, A1
Pletnikov, MV1
Rubin, SA1
Vogel, MW1
Moran, TH1
Carbone, KM1
Tournigant, JC2
Arnaud, O1
Passouant-Fontaine, T2
Yanai, J1
Sze, PY1
Ginsburg, BE1
Rowe, VD1
Fales, HM1
Pisano, JJ1
Andersen, AE1
Guroff, G1
Poncet, IB1
Kazmaier, KJ1
Broitman, ST1
Donoso, AO1
Gallo, RV1
Rabii, J1
Moberg, GP1
Kawakami, M1
Kimura, F1
Kawagoe, S1
González-Barón, S2
Jiménez-Vargas, J4
Weiss, B1
Jui, M1
Lajtha, A1
Balagura, S1
Harrell, LE1
de Castro, JM1
Copenhaver, JH5
Schalock, RL3
Carver, MJ4
Tosar, A1
Satli, MA2
Akeson, AL1
Brunner, RL1
Bond, EF1
Heitkemper, MM1
Gruver, MK1
Mistry, AM1
Voogt, JL2
Mistry, A1
Okano, Y1
Chow, IZ1
Isshiki, G1
Inoue, A1
Oura, T1
Whitaker-Azmitia, PM2
Shemmer, A1
Azmitia, EC2
Kronick, JB1
Whelan, DT1
McCallion, DJ1
Shemer, A1
Horn, AM1
Fink, G1
Towle, AC1
Patrick, K1
Henderson, P1
Ieni, JR1
Thurmond, JB1
Saavedra, JM1
Coyle, JT1
Axelrod, J1
Kieffer, JD1
Harper, MJ1
Salis, PJ1
Dewsbury, DA1
Johnson, EA1
Saxton, MJ1
Hole, K1
Dalló, J1
Held, K1
Barry, J1
Lindstrom, LH1
Greengrass, PM1
Tonge, SR1
Kordon, C2
Gogan, F1
Rotsztejn, WH1
Mack, K2
Vacanti, JP1
Taleisnik, S1
Celis, ME1
Tomatis, ME1
Carrer, H1
Eliasson, M1
Herbert, J1
Del Fiacco, M1
Fratta, W1
Gessa, GL1
Tagliamonte, A1
Moore, WT1
Hampton, JK1
Hansult, CD1
Uphouse, LL1
Schlesinger, K1
Wilson, JR1
Trentini, GP1
Tima, L1
De Gaetani, CF1
Mess, B1
Glowinski, J1
Prohaska, JR1
Wells, WW1
Luecke, RW1

Reviews

4 reviews available for fenclonine and Pregnancy

ArticleYear
Hormone-dependent socio-sexual behaviors and neurotransmitters.
    Progress in brain research, 1984, Volume: 61

    Topics: Animals; beta-Endorphin; Castration; Copulation; Cyclic AMP; Dihydroxyphenylalanine; Dopamine; Endor

1984
Progress in experimental phenylketonuria: a critical review.
    Neuroscience and biobehavioral reviews, 1981,Spring, Volume: 5, Issue:1

    Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Energy Metabolism; Female; Fenclonine; Glu

1981
Some functions of hormones and the hypothalamus in the sexual activity of primates.
    Progress in brain research, 1974, Volume: 41

    Topics: Adrenal Glands; Adrenalectomy; Animals; Castration; Estrus; Female; Fenclonine; Gonadal Steroid Horm

1974
Role of hypothalamic monoaminergic neurones in the gonadotrophin release-regulating mechanisms.
    Neuropharmacology, 1972, Volume: 11, Issue:2

    Topics: Animals; Dihydroxyphenylalanine; Dopamine; Female; Fenclonine; Gonadotropins; Horses; Hypothalamus;

1972

Other Studies

96 other studies available for fenclonine and Pregnancy

ArticleYear
Serotonin disruption at gestation alters expression of genes associated with serotonin synthesis and reuptake at weaning.
    Psychopharmacology, 2022, Volume: 239, Issue:10

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Dopamine; Ethanol; Female; Fenclonine; Humans; Male;

2022
Maternal Inflammation Disrupts Fetal Neurodevelopment via Increased Placental Output of Serotonin to the Fetal Brain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 06-01, Volume: 36, Issue:22

    Topics: 5-Hydroxytryptophan; Animals; Brain; Cytokines; Disease Models, Animal; Female; Fenclonine; Fetal De

2016
Maternal para-chlorophenylalanine exposure modifies central monoamines and behaviors in the adult offspring.
    Brain research, 2008, Oct-09, Volume: 1234

    Topics: Animals; Anxiety; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Environment; Female; Fencl

2008
Effects of prenatal stress and monoaminergic perturbations on the expression of serotonin 5-HT₄ and adrenergic β₂ receptors in the embryonic mouse telencephalon.
    Brain research, 2012, Jun-12, Volume: 1459

    Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Analysis of Variance; A

2012
[Participation of serotonin in the mechanisms of the formation of trigeminal motor nucleus].
    Morfologiia (Saint Petersburg, Russia), 2012, Volume: 142, Issue:5

    Topics: Animals; Cell Death; Embryonic Development; Female; Fenclonine; Motor Neurons; Neuropil; Nissl Bodie

2012
Influence of serotonin on the development and migration of gonadotropin-releasing hormone neurones in rat foetuses.
    Journal of neuroendocrinology, 2003, Volume: 15, Issue:6

    Topics: Animals; Cell Differentiation; Cell Movement; Enzyme Inhibitors; Female; Fenclonine; Gestational Age

2003
The effects of serotonin on the differentiation of neurons producing vasoactive intestinal polypeptide in the suprachiasmatic nucleus of the rat.
    Neuroscience and behavioral physiology, 2003, Volume: 33, Issue:7

    Topics: Animals; Cell Differentiation; Female; Fenclonine; Male; Neurons; Pregnancy; Prenatal Exposure Delay

2003
Decreased serotonin level during pregnancy alters morphological and functional characteristics of tonic nociceptive system in juvenile offspring of the rat.
    Reproductive biology and endocrinology : RB&E, 2003, Nov-13, Volume: 1

    Topics: Animals; Birth Weight; Brain; Brain Chemistry; Efferent Pathways; Female; Fenclonine; Fetus; Gestati

2003
Elimination of serotonergic cells induces a marked increase in generation of dopaminergic neurons from mesencephalic precursors.
    The European journal of neuroscience, 2003, Volume: 18, Issue:8

    Topics: 5,6-Dihydroxytryptamine; Animals; Apoptosis; Benzimidazoles; Bromodeoxyuridine; Cell Count; Cells, C

2003
Serotonin regulates mammary gland development via an autocrine-paracrine loop.
    Developmental cell, 2004, Volume: 6, Issue:2

    Topics: Animals; Animals, Newborn; Aromatic-L-Amino-Acid Decarboxylases; Autocrine Communication; Caseins; C

2004
Long-lasting effects of serotonin deficiency on differentiating peptidergic neurons in the rat suprachiasmatic nucleus.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2005, Volume: 23, Issue:1

    Topics: Analysis of Variance; Animals; Diagnostic Imaging; Female; Fenclonine; Immunohistochemistry; In Situ

2005
[Astroglia formation in the neocortex of mice after temporary prenatal serotonin depletion].
    Morfologiia (Saint Petersburg, Russia), 2005, Volume: 127, Issue:1

    Topics: Animals; Animals, Newborn; Astrocytes; Cell Differentiation; Embryo, Mammalian; Female; Fenclonine;

2005
Formation of the astroglia in the mouse neocortex after temporary prenatal blockade of serotonin synthesis.
    Neuroscience and behavioral physiology, 2006, Volume: 36, Issue:3

    Topics: Animals; Animals, Newborn; Astrocytes; Cell Differentiation; Chimera; Embryo, Mammalian; Female; Fen

2006
Formation of the neocortex in mice developing in conditions of prenatal serotonin deficiency.
    Neuroscience and behavioral physiology, 2006, Volume: 36, Issue:5

    Topics: Animals; Cell Differentiation; Enzyme Inhibitors; Female; Fenclonine; Mice; Mice, Inbred C57BL; Mice

2006
Embryonic depletion of serotonin affects cortical development.
    The European journal of neuroscience, 2007, Volume: 26, Issue:2

    Topics: Animals; Blotting, Western; Body Weight; Brain-Derived Neurotrophic Factor; Calbindin 2; Cell Count;

2007
Behavioral alteration in the adult rats prenatally exposed to para-chlorophenylalanine.
    Brain research, 2007, Sep-12, Volume: 1169

    Topics: Aging; Animals; Avoidance Learning; Behavior, Animal; Brain; Brain Chemistry; Exploratory Behavior;

2007
Serotonin is involved in the regulation of histogenetic processes in rat embryonic neocortex.
    Bulletin of experimental biology and medicine, 2007, Volume: 143, Issue:3

    Topics: Animals; Cell Differentiation; Cell Proliferation; Cell Survival; Female; Fenclonine; Fetal Tissue T

2007
Phenylacetate and brain dysfunction in experimental phenylketonuria: synaptic development.
    Life sciences, 1980, Oct-06, Volume: 27, Issue:14

    Topics: Animals; Cerebral Cortex; Choline; Female; Fenclonine; gamma-Aminobutyric Acid; Humans; Male; Neurot

1980
Reinstatement of LH surges by serotonin neuroleptics in aging, constant estrous rats.
    Neurobiology of aging, 1982,Fall, Volume: 3, Issue:3

    Topics: 5-Hydroxytryptophan; Aging; alpha-Methyltyrosine; Animals; Antipsychotic Agents; Castration; Estradi

1982
Lack of long term effect of p-chlorophenylalanine on brain 5-hydroxytryptamine and electrocortical activity in conscious fetal sheep.
    Experientia, 1984, Mar-15, Volume: 40, Issue:3

    Topics: Animals; Brain; Electroencephalography; Electromyography; Female; Fenclonine; Hydroxyindoleacetic Ac

1984
A study of placental transfer mechanisms in nonhuman primates using [14C]phenylalanine.
    Obstetrics and gynecology, 1982, Volume: 59, Issue:2

    Topics: Animals; Carbon Radioisotopes; Female; Fenclonine; Fetal Blood; Macaca fascicularis; Macaca mulatta;

1982
[Effect of p-chlorophenylalanine on LH, FSH, prolactin and ovulation in the rat].
    Revista espanola de fisiologia, 1982, Volume: 38, Issue:3

    Topics: Animals; Estrus; Female; Fenclonine; Follicle Stimulating Hormone; Luteinizing Hormone; Ovary; Ovula

1982
Serotonergic control of oxytocin release during suckling in the rat: opposite effects in conscious and anesthetized rats.
    Neuroendocrinology, 1983, Volume: 36, Issue:4

    Topics: Anesthesia; Animals; Animals, Suckling; Cyproheptadine; Female; Fenclonine; Fluoxetine; Lactation; O

1983
[Effect of ethanol in preovulatory periods on LH, FSH, prolactin and ovulation in rats].
    Revista espanola de fisiologia, 1983, Volume: 39, Issue:1

    Topics: Animals; Estrus; Ethanol; Female; Fenclonine; Follicle Stimulating Hormone; Hypothalamo-Hypophyseal

1983
Roles for serotonin in neurogenesis.
    Monographs in neural sciences, 1983, Volume: 9

    Topics: Animals; Brain; Cell Differentiation; Cells, Cultured; Female; Fenclonine; Maternal-Fetal Exchange;

1983
Placental transfer of aromatic amino acids in non-human primates.
    Acta obstetricia et gynecologica Scandinavica, 1983, Volume: 62, Issue:5

    Topics: Amino Acids; Amniotic Fluid; Animals; Female; Fenclonine; Fetal Blood; Macaca fascicularis; Maternal

1983
Analysis of learning in retarded monkeys.
    Journal of mental deficiency research, 1984, Volume: 28 (Pt 1)

    Topics: Animals; Attention; Concept Formation; Discrimination, Psychological; Disease Models, Animal; Female

1984
Placental transfer of phenylalanine in Macaca mulatta and Macaca fascicularis.
    Journal of medical primatology, 1983, Volume: 12, Issue:5

    Topics: Animals; Female; Fenclonine; Fetal Blood; Macaca; Macaca fascicularis; Macaca mulatta; Maternal-Feta

1983
Constant estrus: role of rostral hypothalamic monoamines in development of reproductive dysfunction in aging rats.
    Endocrinology, 1980, Volume: 107, Issue:1

    Topics: Aging; Animals; Catecholamines; Diestrus; Disease Models, Animal; Ditiocarb; Estrus; Female; Fenclon

1980
Dietary and metabolic effects on rhesus social behavior: phenylalanine-related dietary alterations.
    Developmental psychobiology, 1980, Volume: 13, Issue:3

    Topics: Aggression; Animals; Female; Fenclonine; Haplorhini; Humans; Macaca mulatta; Phenylalanine; Phenylke

1980
Loss of serotonin circadian rhythms in the pineal gland of androgenized female rats.
    Neuroendocrinology, 1980, Volume: 31, Issue:4

    Topics: Aging; Animals; Circadian Rhythm; Estrus; Female; Fenclonine; Hypothyroidism; Luteinizing Hormone; P

1980
Effects of manipulating serotonin on the incidence of ovulation in the rat.
    The Journal of endocrinology, 1980, Volume: 87, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Estradiol; Estrogens; Estrus; Female; Fenclonine; Injection

1980
Phenylacetate and the enduring behavioral deficit in experimental phenylketonuria.
    Life sciences, 1980, Oct-06, Volume: 27, Issue:14

    Topics: Animals; Behavior, Animal; Body Weight; Escape Reaction; Female; Fenclonine; Humans; Hyperkinesis; M

1980
[The effect of a serotonin deficiency on the hypothalamo-hypophyseal-gonadal system in rat fetuses].
    Biulleten' eksperimental'noi biologii i meditsiny, 1994, Volume: 117, Issue:6

    Topics: Animals; Female; Fenclonine; Fetus; Gonads; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Mal

1994
Development of chemosensitivity in serotonin-deficient spinal cords of rat embryos.
    Developmental biology, 1993, Volume: 158, Issue:1

    Topics: Animals; Female; Fenclonine; Ketanserin; Membrane Potentials; Motor Neurons; Pregnancy; Rats; Recept

1993
[An experimental study on the effects of maternal hyperphenylalaninemia on the central nervous system and behavior of offspring rats].
    Anales espanoles de pediatria, 1998, Volume: 48, Issue:1

    Topics: Amino Acids, Branched-Chain; Animals; Animals, Newborn; Behavior, Animal; Brain; Enzyme Inhibitors;

1998
Prenatal administration of para-chlorophenylalanine results in suppression of serotonergic system and disturbance of swimming movements in newborn rats.
    Neuroscience research, 1998, Volume: 31, Issue:2

    Topics: Animals; Animals, Newborn; Female; Fenclonine; Forelimb; Hindlimb; Motor Activity; Motor Neurons; Pr

1998
Receptors and neurotransmitters involved in the dual modulation of prolactin release by the serotoninergic system in pregnant and lactating rats.
    Journal of reproduction and fertility, 1999, Volume: 116, Issue:2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergi

1999
Serotonin mediates oestrogen stimulation of cell proliferation in the adult dentate gyrus.
    The European journal of neuroscience, 2001, Volume: 14, Issue:9

    Topics: 5-Hydroxytryptophan; Animals; Astrocytes; Bromodeoxyuridine; Cell Count; Cell Division; Dentate Gyru

2001
Effects of genetic background on neonatal Borna disease virus infection-induced neurodevelopmental damage. II. Neurochemical alterations and responses to pharmacological treatments.
    Brain research, 2002, Jul-19, Volume: 944, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animal Diseases; Animals; Animals, Newborn; Borna Disease; B

2002
[Effect of hypothalamic implants changing monoamine levels on continuous estrus in rats induced by androgen treatment in the neonatal period].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1975, Volume: 169, Issue:1

    Topics: Adrenergic Agents; Animals; Animals, Newborn; Dopamine; Drug Implants; Estrus; Female; Fenclonine; H

1975
Effects of aminergic drugs and glutamic acid on audiogenic seizures induced by early exposure to ethanol.
    Epilepsia, 1975, Volume: 16, Issue:1

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Behavior, Animal; Dihydroxyphenylalanine; Drug I

1975
Urinary metabolites of phenylalanine in the preweanling rat treated with p-chlorophenylalanine and phenylalanine.
    Biochemical medicine, 1975, Volume: 12, Issue:2

    Topics: Animals; Chromatography; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fenclonin

1975
Biochemical effects of induced phenylketonuria in rats.
    Biology of the neonate, 1975, Volume: 26, Issue:1-2

    Topics: Amino Acids; Amniotic Fluid; Animals; Brain; Diet; Female; Fenclonine; Fetal Blood; Humans; Phenylac

1975
Modifications of post-coital LH secretion and oestrous behaviour induced by drugs in ovariectomized rats.
    Journal of reproduction and fertility, 1975, Volume: 44, Issue:2

    Topics: Amphetamine; Animals; Castration; Copulation; Estradiol; Estrus; Female; Fenclonine; Luteinizing Hor

1975
Effect of methysergide, a blocker of serotonin receptors, on plasma prolactin levels in lactating and ovariectomized rats.
    Endocrinology, 1975, Volume: 97, Issue:5

    Topics: Animals; Brain; Castration; Female; Fenclonine; Hypophysectomy; Lactation; Methysergide; Ovary; Pitu

1975
Effects of p-chlorophenylalanine on time of neuronal origin during embryogenesis in the rat.
    Brain research, 1976, May-14, Volume: 107, Issue:3

    Topics: Animals; Brain; Cell Differentiation; Female; Fenclonine; Glucocorticoids; Maternal-Fetal Exchange;

1976
Cholinergic and serotonergic neural links and the inhibitory effects of hippocampus, lateral amygdala and central gray matter on gonadotropin release.
    Endocrinologia japonica, 1976, Volume: 23, Issue:1

    Topics: Amygdala; Animals; Atropine; Biogenic Amines; Electric Stimulation; Female; Fenclonine; Follicle Sti

1976
[Serotoninergic and adrenergic factors influencing the ovulation and reproduction in the rat].
    Revista de medicina de la Universidad de Navarra, 1975, Volume: 19, Issue:1

    Topics: Animals; Estrus; Female; Fenclonine; Hydroxydopamines; Light; Ovary; Ovulation; Pregnancy; Rats; Rep

1975
Entrapment of phenylalanine hydroxylase in a polyacrylamide matrix.
    Biochemical medicine, 1977, Volume: 18, Issue:3

    Topics: Acrylamides; Animals; Dithiothreitol; Drug Stability; Enzymes, Immobilized; Female; Fenclonine; Kine

1977
Organismic states and their effect on recovery from neurosurgery: a new perspective with implications for a general theory.
    Brain, behavior and evolution, 1978, Volume: 15, Issue:1

    Topics: Animals; Behavior, Animal; Body Weight; Brain; Castration; Female; Fenclonine; Glucagon; Hippocampus

1978
para-Chloro-D, L-phenylalanine induced filicidal behavior in the female rat.
    Pharmacology, biochemistry, and behavior, 1978, Volume: 8, Issue:3

    Topics: Aggression; Animals; Animals, Newborn; Brain Chemistry; Feeding Behavior; Female; Fenclonine; Humans

1978
[Reflex factors that modify the effect of p-chlorophenylalanine on ovulation and reproduction in rats (author's transl)].
    Revista espanola de fisiologia, 1978, Volume: 34, Issue:1

    Topics: Animals; Estrus; Fallopian Tubes; Female; Fenclonine; Ovary; Ovulation; Pregnancy; Rats; Reflex; Rep

1978
[New data on serotonin control of sexual receptivity in the rat].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1978, May-02, Volume: 286, Issue:17

    Topics: Animals; Female; Fenclonine; Male; Olfactory Bulb; Pregnancy; Proestrus; Rats; Serotonin; Sexual Beh

1978
Brain pyruvate kinase activity in PKU model systems.
    Journal of neurochemistry, 1979, Volume: 32, Issue:1

    Topics: Animals; Body Weight; Brain; Female; Fenclonine; Fetus; Humans; Organ Size; Phenylalanine; Phenylket

1979
[Modification of the ovarian cycle, ovulation and reproduction in rat by administration of p-chlorophenylalanine in the pre and post ovulation period (author's transl)].
    Revista espanola de fisiologia, 1979, Volume: 35, Issue:1

    Topics: Animals; Estrus; Female; Fenclonine; Ovary; Ovulation; Pregnancy; Rats; Reproduction; Time Factors

1979
[Supression by copulation of the inhibitory effect of p-chlorophenylalanine on rat ovulation (author's transl)].
    Revista espanola de fisiologia, 1979, Volume: 35, Issue:1

    Topics: Animals; Copulation; Estrus; Female; Fenclonine; Injections, Intraperitoneal; Male; Ovulation; Pregn

1979
Serotonin involvement in the control of phasic luteinizing hormone release in the rat: evidence for a critical period.
    The Journal of endocrinology, 1979, Volume: 82, Issue:1

    Topics: 5-Hydroxytryptophan; 5,6-Dihydroxytryptamine; Animals; Castration; Circadian Rhythm; Estradiol; Fema

1979
[New data on serotoninergic mechanisms in ovulation in the cyclic female rat].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1979, Volume: 173, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Diestrus; Estradiol; Female; Fenclonine; Ovulation; Pregnancy; Proestr

1979
Serotonin as a differentiation signal in early neurogenesis.
    Developmental neuroscience, 1978, Volume: 1, Issue:1

    Topics: Animals; Brain; Cell Differentiation; Female; Fenclonine; Hippocampus; Neurons; Pregnancy; Raphe Nuc

1978
Mediation of thyrotropin-releasing hormone induced gastric motility increases in developing rats.
    European journal of pharmacology, 1992, Jul-07, Volume: 217, Issue:2-3

    Topics: Aging; Analysis of Variance; Animals; Atropine; Dose-Response Relationship, Drug; Drug Interactions;

1992
Serotonin synthesis inhibition or receptor antagonism reduces pregnancy-induced nocturnal prolactin secretion.
    Life sciences, 1990, Volume: 47, Issue:8

    Topics: Analysis of Variance; Animals; Biogenic Monoamines; Dorsomedial Hypothalamic Nucleus; Dose-Response

1990
Role of serotonin in nocturnal and diurnal surges of prolactin in the pregnant rat.
    Endocrinology, 1989, Volume: 125, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Circadian Rhythm; Dopamine; Ergolines; Female; Fenclonine;

1989
Effects of phenylalanine loading on protein synthesis in the fetal heart and brain of rat: an experimental approach to maternal phenylketonuria.
    Journal of inherited metabolic disease, 1986, Volume: 9, Issue:1

    Topics: Animals; Brain; Carbon Radioisotopes; Disease Models, Animal; Female; Fenclonine; Fetal Heart; Fetus

1986
Relationships among maternal and fetal amino acid blood concentrations and amniotic fluid amino acid levels in pregnant rhesus monkeys.
    Acta obstetricia et gynecologica Scandinavica, 1986, Volume: 65, Issue:8

    Topics: Amino Acids; Amniotic Fluid; Animals; Female; Fenclonine; Fetal Blood; Macaca mulatta; Phenylalanine

1986
A possible dual regulation of prolactin release by the serotoninergic system in rats at pro-oestrus and during late pregnancy: role of ovarian hormones.
    The Journal of endocrinology, 1987, Volume: 112, Issue:3

    Topics: Animals; Estradiol; Estrus; Female; Fenclonine; Humans; Methiothepin; Ovariectomy; Pregnancy; Pregna

1987
Postnatal changes in serotonin receptors following prenatal alterations in serotonin levels: further evidence for functional fetal serotonin receptors.
    Brain research, 1987, Volume: 430, Issue:2

    Topics: 5-Methoxytryptamine; Animals; Animals, Newborn; Brain; Brain Stem; Female; Fenclonine; Fetus; Kineti

1987
Experimental hyperphenylalaninemia in the pregnant guinea pig: possible phenylalanine teratogenesis and p-chlorophenylalanine embryotoxicity.
    Teratology, 1987, Volume: 36, Issue:2

    Topics: Animals; Embryonic and Fetal Development; Female; Fenclonine; Fetal Death; Guinea Pigs; Liver; Mater

1987
Effect of serotonin antagonists on prolactin and progesterone secretion in rats: evidence that the stimulatory and inhibitory actions of serotonin on prolactin release may be mediated through different receptors.
    The Journal of endocrinology, 1988, Volume: 117, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Female; Fenclonine; Fluoxetine; Indoles; Ketanserin; Pregnancy; Proest

1988
Effects of prenatal 5-methoxytryptamine and parachlorophenylalanine on serotonergic uptake and behavior in the neonatal rat.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:4

    Topics: 5-Methoxytryptamine; Animals; Animals, Newborn; Avoidance Learning; Brain; Brain Stem; Female; Fencl

1988
Parachlorophenylalanine blocks the spontaneous pro-oestrous surge of prolactin as well as LH and affects the secretion of oestradiol-17 beta.
    The Journal of endocrinology, 1985, Volume: 104, Issue:3

    Topics: Animals; Estradiol; Estrus; Female; Fenclonine; Luteinizing Hormone; Ovary; Pregnancy; Proestrus; Pr

1985
Decreased serotonin content of embryonic raphe neurons following maternal administration of p-chlorophenylalanine: a quantitative immunocytochemical study.
    Brain research, 1985, Volume: 352, Issue:1

    Topics: Animals; Female; Fenclonine; Histocytochemistry; Immunochemistry; Maternal-Fetal Exchange; Pregnancy

1985
Maternal aggression in mice: effects of treatments with PCPA, 5-HTP and 5-HT receptor antagonists.
    European journal of pharmacology, 1985, May-08, Volume: 111, Issue:2

    Topics: 5-Hydroxytryptophan; Aggression; Animals; Biogenic Amines; Brain Chemistry; Female; Fenclonine; Huma

1985
Developmental characteristics of phenylethanolamine and octopamine in the rat brain.
    Journal of neurochemistry, 1974, Volume: 23, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Brain; Chromatography, Thin Layer; Dopamine beta-Hydroxylase; Etha

1974
Induction of pseudopregnancy in rats by p-chlorophenylalanine.
    Nature, 1971, May-14, Volume: 231, Issue:5298

    Topics: Animals; Body Weight; Brain; Female; Fenclonine; Norepinephrine; Organ Size; Ovary; Phenylalanine; P

1971
p-chlorophenylalanine facilitates copulatory behaviour in male rats.
    Nature, 1971, Aug-06, Volume: 232, Issue:5310

    Topics: Analysis of Variance; Animals; Appetitive Behavior; Copulation; Ejaculation; Estradiol; Estrus; Fema

1971
Effect of para-chlorophenylalanine on the growth and development of the fetal, neonatal, and adult rat.
    Biochemical medicine, 1970, Volume: 4, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Body Weight; Brain; Feeding Behavior; Female; Fenclonine; Fetus; G

1970
Reduced 5-hydroxyindole synthesis reduces postnatal brain growth in rats.
    European journal of pharmacology, 1972, Volume: 18, Issue:3

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Body Weight; Brain; Brain Chemistry; Drug Interactions; F

1972
Drugs and sexual behaviour in rats.
    Activitas nervosa superior, 1972, Volume: 14, Issue:4

    Topics: Animals; Estrus; Female; Fenclonine; Male; Maternal Behavior; Methamphetamine; Norethynodrel; Pregna

1972
[Ultraviolet fluorescence study of central monoamines in female androgenized rats during the neonatal period and in blinded female rats].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1972, Volume: 166, Issue:1

    Topics: Animals; Blindness; Brain Chemistry; Dopamine; Electric Stimulation; Estrus; Female; Fenclonine; Flu

1972
The effect of pilocarpine and oxotremorine on oestrous behaviour in female rats after treatment with monoamine depletors or monoamine synthesis inhibitors.
    European journal of pharmacology, 1971, Volume: 15, Issue:1

    Topics: Amines; Animals; Castration; Estradiol; Estrus; Female; Fenclonine; Humans; Methyltyrosines; Pilocar

1971
Brain monoamine metabolism in the mouse during the immediate post-partum period.
    British journal of pharmacology, 1972, Volume: 46, Issue:3

    Topics: Amines; Animals; Brain; Dopamine; Estrus; Female; Fenclonine; Hydroxyindoleacetic Acid; Mice; Norepi

1972
Interference of serotonin-containing neurons with pituitary gonadotropins release-regulation.
    Gynecologic investigation, 1971, Volume: 2, Issue:1

    Topics: Animals; Estradiol; Feedback; Female; Fenclonine; Gonadotropins, Pituitary; Hypothalamus; Lactation;

1971
Effect of hyperphenylalaninemia on vitamin B 6 metabolism in developing rat brain.
    Journal of neurochemistry, 1972, Volume: 19, Issue:10

    Topics: Animals; Brain; Carbon Isotopes; Chromatography, Ion Exchange; Female; Fenclonine; Humans; Injection

1972
Effect of vitamin B 6 on phenylalanine metabolism in the brain of normal and p-chlorophenylalanine-treated rats.
    Journal of neurochemistry, 1972, Volume: 19, Issue:10

    Topics: Animals; Brain; Carbon Isotopes; Female; Fenclonine; Humans; Injections, Intraperitoneal; Injections

1972
Experimental maternal hyperphenylalaninemia: disaggregation of fetal brain ribosomes.
    Journal of neurochemistry, 1973, Volume: 21, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Centrifugation, Density Gradient; Female; Fenclonine; Fetus; Humans

1973
Behavioral effects of experimental maternal hyperphenylalaninemia.
    Developmental psychobiology, 1973, Volume: 6, Issue:6

    Topics: Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Disease Models, Animal; Exploratory

1973
Experimental maternal hyperphenylalaninemia: biochemical effects and offspring development.
    Developmental psychobiology, 1974, Volume: 7, Issue:2

    Topics: Aggression; Animals; Animals, Newborn; Body Weight; Brain; Brain Chemistry; Disease Models, Animal;

1974
Release of melanocyte-stimulating hormone by several stimuli through the activation of a 5-hydroxytryptamine-mediated inhibitory neuronal mechanism.
    Neuroendocrinology, 1974, Volume: 13, Issue:6

    Topics: Aminobutyrates; Animals; Breast Feeding; Depression, Chemical; Dibenzylchlorethamine; Estrus; Female

1974
5-Hydroxytryptamine and sexual behavior in the female rat.
    Advances in biochemical psychopharmacology, 1974, Volume: 11, Issue:0

    Topics: Amino Acids; Animals; Apomorphine; Castration; Circadian Rhythm; Electroshock; Estrus; Exploratory B

1974
[Disturbance of the rat estrus cycle by hypothalamic implants acting on monoamines].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1973, Volume: 167, Issue:12

    Topics: Amines; Animals; Dopamine; Estrus; Female; Fenclonine; Hydroxydopamines; Hypothalamus; Nialamide; Ov

1973
Lack of copulatory behaviour in male castrated rats after p-chlorophenylalanine.
    British journal of pharmacology, 1974, Volume: 51, Issue:2

    Topics: Animals; Brain Chemistry; Castration; Estrus; Female; Fenclonine; Hydroxyindoleacetic Acid; Male; Pr

1974
Effects of para-chlorophenylalanine on pregnancy in the rat.
    Biology of reproduction, 1974, Volume: 11, Issue:3

    Topics: Adrenal Glands; Animals; Body Weight; Brain; Delivery, Obstetric; Female; Fenclonine; Fetal Death; F

1974
Induction of estrus in mice: hypophyseal-adrenal effects.
    Hormones and behavior, 1972, Volume: 3, Issue:2

    Topics: Adrenalectomy; Animals; Estradiol; Estrus; Female; Fenclonine; Hypophysectomy; Methyltyrosines; Mice

1972
Luteinization induced by p-chlorophenylalanine treatment in constant oestrous anovulatory rats.
    Steroids and lipids research, 1974, Volume: 5, Issue:4

    Topics: Animals; Anovulation; Estrus; Female; Fenclonine; Gonadotropin-Releasing Hormone; Hypothalamus; Mese

1974
Effect of phenylalanine and p-chlorophenylalanine administration on the development of rat brain 2',3'-cyclic nucleotide 3'-phosphohydrolase.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 147, Issue:2

    Topics: Age Factors; Animals; Body Weight; Brain; Cerebellum; Electron Transport Complex IV; Female; Fenclon

1974