fenclonine has been researched along with Nerve Degeneration in 9 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has been reported that fluoxetine, a selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitor, has neuroprotective properties in the lithium-pilocarpine model of status epilepticus (SE) in rats." | 7.83 | Serotonin Depletion Does not Modify the Short-Term Brain Hypometabolism and Hippocampal Neurodegeneration Induced by the Lithium-Pilocarpine Model of Status Epilepticus in Rats. ( Bascuñana, P; de Cristóbal, J; Delgado, M; Fernández de la Rosa, R; García-García, L; Pozo, MA; Shiha, AA, 2016) |
| "It has been reported that fluoxetine, a selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitor, has neuroprotective properties in the lithium-pilocarpine model of status epilepticus (SE) in rats." | 3.83 | Serotonin Depletion Does not Modify the Short-Term Brain Hypometabolism and Hippocampal Neurodegeneration Induced by the Lithium-Pilocarpine Model of Status Epilepticus in Rats. ( Bascuñana, P; de Cristóbal, J; Delgado, M; Fernández de la Rosa, R; García-García, L; Pozo, MA; Shiha, AA, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| García-García, L | 1 |
| Shiha, AA | 1 |
| Bascuñana, P | 1 |
| de Cristóbal, J | 1 |
| Fernández de la Rosa, R | 1 |
| Delgado, M | 1 |
| Pozo, MA | 1 |
| Moroni, F | 1 |
| Lombardi, G | 1 |
| Carlà, V | 1 |
| Moneti, G | 1 |
| Amar, A | 1 |
| Mandal, S | 1 |
| Sanyal, AK | 1 |
| Hardin, H | 1 |
| Bernard, A | 1 |
| Rajas, F | 1 |
| Fevre-Montange, M | 1 |
| Derrington, E | 1 |
| Belin, MF | 1 |
| Didier-Bazes, M | 1 |
| Romijn, HJ | 1 |
| Avins, L | 1 |
| Guroff, G | 1 |
| Kuwabara, T | 1 |
| Herman, ZS | 1 |
| Euvrard, C | 1 |
| Javoy, F | 1 |
| Herbet, A | 1 |
| Glowinski, J | 1 |
| Andén, NE | 1 |
1 review available for fenclonine and Nerve Degeneration
| Article | Year |
|---|---|
5-hydroxytryptamine metabolism in the brain under the influence of psychotropic drugs.
Topics: Amphetamine; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Brain; Fenclonine; Hallucinoge | 1975 |
8 other studies available for fenclonine and Nerve Degeneration
| Article | Year |
|---|---|
Serotonin Depletion Does not Modify the Short-Term Brain Hypometabolism and Hippocampal Neurodegeneration Induced by the Lithium-Pilocarpine Model of Status Epilepticus in Rats.
Topics: Animals; Disease Models, Animal; Fenclonine; Gliosis; Hippocampus; Lithium; Magnetic Resonance Imagi | 2016 |
The excitotoxin quinolinic acid is present and unevenly distributed in the rat brain.
Topics: 5,7-Dihydroxytryptamine; Animals; Brain Chemistry; Fenclonine; Male; Mass Spectrometry; Nerve Degene | 1984 |
Effect of brain monoamines on the secretion of adrenocorticotrophic hormone.
Topics: 5,6-Dihydroxytryptamine; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Benztropine; Brain Ch | 1982 |
Modifications of glial metabolism of glutamate after serotonergic neuron degeneration in the hippocampus of the rat.
Topics: 5,7-Dihydroxytryptamine; Animals; Astrocytes; Cell Communication; Fenclonine; Gene Expression; Glial | 1994 |
Structure and innervation of the pineal gland of the rabbit, Oryctolagus cuniculus (L.). III. An electron microscopic investigation of the innervation.
Topics: Acetylcholinesterase; Animals; Axons; Cytological Techniques; Facial Nerve; Fenclonine; Ganglia, Spi | 1975 |
Ultrastructural changes in rat optic nerve associated with hyperphenylalaninemia induced by para-chlorophenylalanine and phenylalanine.
Topics: Animals; Astrocytes; Axons; Cytoplasm; Disease Models, Animal; Endoplasmic Reticulum; Fenclonine; Go | 1975 |
Effect of quipazine, a serotonin-like drug, on striatal cholinergic interneurones.
Topics: Acetylcholine; Animals; Brain Chemistry; Choline O-Acetyltransferase; Cholinesterases; Corpus Striat | 1977 |
Effect of acute axotomy (spinal cord transection) on the turnover of 5-hydroxytryptamine.
Topics: Acetamides; Amphetamine; Animals; Catechols; Fenclonine; Hallucinogens; Hydroxyindoleacetic Acid; Ly | 1974 |