Page last updated: 2024-11-02

fenclonine and Muscle Contraction

fenclonine has been researched along with Muscle Contraction in 14 studies

Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" A muscarinic agonist, carbachol, produced a dose-related rightward shift of the dose-response curve to IMI."1.30Suppression of the rat micturition reflex by imipramine. ( Kim, CY; Sohn, UD, 1997)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199010 (71.43)18.7374
1990's3 (21.43)18.2507
2000's1 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kitazawa, T1
Gonella, J1
Haga, N1
Mizuki, A1
Sato, M1
Mochiki, H1
Sato, S1
Sohn, UD1
Kim, CY1
Fuenmayor, L1
Gomez, J1
Campos, HA1
Romero, E1
Cooper, RL1
Chase, RJ1
Tabor, J1
Vogt, M1
Clineschmidt, BV1
McGuffin, JC1
Rodríguez, R1
Luján, M1
Campos, AE1
Chroné, R1
Bond, EF1
Heitkemper, MM1
Gruver, MK1
Gunning, SJ1
Bradbury, AJ1
Costall, B1
Naylor, RJ1
Hoffmann, P1
Thorén, P1
Woodruff, GN1
Elkhawad, AO1
Pinder, RM1
Marley, E1
Whelan, JE1

Other Studies

14 other studies available for fenclonine and Muscle Contraction

ArticleYear
Evidences that endogenous 5-hydroxytryptamine participates in the contractile response to morphine in the rat isolated colon.
    The Kitasato archives of experimental medicine, 1984, Volume: 57, Issue:1

    Topics: Acetylcholine; Animals; Cold Temperature; Colon; Dose-Response Relationship, Drug; Female; Fenclonin

1984
The physiological role of peripheral serotoninergic neurones. A review.
    Journal de physiologie, 1981, Volume: 77, Issue:2-3

    Topics: Animals; Clomipramine; Electric Stimulation; Fenclonine; Muscle Contraction; Muscle, Smooth; Myenter

1981
[The role of endogenous serotonin in interdigestive gastric contraction].
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1995, Volume: 31, Issue:6

    Topics: 5,6-Dihydroxytryptamine; Animals; Dogs; Fenclonine; Gastric Mucosa; Muscle Contraction; Muscle, Smoo

1995
Suppression of the rat micturition reflex by imipramine.
    Journal of autonomic pharmacology, 1997, Volume: 17, Issue:1

    Topics: Adrenergic Uptake Inhibitors; alpha-Methyltyrosine; Animals; Antidepressive Agents, Tricyclic; Atrop

1997
Presence of serotonin in the rat vas deferens: its influence on contractile responses.
    Neuroscience, 1976, Volume: 1, Issue:3

    Topics: Animals; Denervation; Electric Stimulation; Fenclonine; Male; Muscle Contraction; Muscle, Smooth; Ra

1976
Altered responsiveness to 5-HT at the crayfish neuromuscular junction due to chronic p-CPA and m-CPP treatment.
    Brain research, 2001, Oct-19, Volume: 916, Issue:1-2

    Topics: Aggression; Animals; Astacoidea; Behavior, Animal; Down-Regulation; Drug Administration Schedule; Dr

2001
The third Thudichum Lecture: Some incidents in the search for chemical transmitters in the brain.
    Biochemical Society transactions, 1977, Volume: 5, Issue:6

    Topics: Acetylcholine; Animals; Anura; Brain; Cats; Dogs; Dopamine; Fenclonine; Homovanillic Acid; Hydroxyin

1977
Pharmacological differentiation of the central 5-hydroxytryptamine-like actions of MK-212 (6-chloro-2[1-piperazinyl]-pyrazine),p-methoxyamphetamine and fenfluramine in an in vivo model system.
    European journal of pharmacology, 1978, Aug-15, Volume: 50, Issue:4

    Topics: Amphetamines; Animals; Dextroamphetamine; Drug Interactions; Fenclonine; Fenfluramine; Fluoxetine; I

1978
Morphine dependence in the isolated guinea-pig ileum and its modification by p-chlorophenylalanine.
    Life sciences, 1978, Sep-04, Volume: 23, Issue:9

    Topics: Animals; Female; Fenclonine; Guinea Pigs; Humans; Ileum; Male; Morphine Dependence; Muscle Contracti

1978
Mediation of thyrotropin-releasing hormone induced gastric motility increases in developing rats.
    European journal of pharmacology, 1992, Jul-07, Volume: 217, Issue:2-3

    Topics: Aging; Analysis of Variance; Animals; Atropine; Dose-Response Relationship, Drug; Drug Interactions;

1992
Evidence that 5-hydroxytryptamine may exert both facilitatory and inhibitory control of electrical field stimulation-evoked contractions in longitudinal muscle taken from the body of guinea-pig stomach.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Electric Stimulation; Fenclonine; Guinea Pigs; In Vitro Techniques; Ma

1986
Electric muscle stimulation in the hind leg of the spontaneously hypertensive rat induces a long-lasting fall in blood pressure.
    Acta physiologica Scandinavica, 1988, Volume: 133, Issue:2

    Topics: Afferent Pathways; Animals; Blood Pressure; Bupivacaine; Electric Stimulation; Fenclonine; Heart Rat

1988
Long lasting stimulation of locomotor activity produced by the intraventricular injection of a cyclic analogue of dopamine into conscious mice.
    European journal of pharmacology, 1974, Volume: 25, Issue:1

    Topics: Animals; Blood Pressure; Cerebral Ventricles; Cyclization; Dopamine; Fenclonine; Haloperidol; Heart

1974
Proceedings: Some unexpected pharmacological effects of p-chlorophenylalanine methyl ester (PCPA) methyl ester).
    British journal of pharmacology, 1974, Volume: 52, Issue:1

    Topics: Adrenal Medulla; Animals; Cats; Dogs; Female; Fenclonine; Guinea Pigs; Ileum; In Vitro Techniques; M

1974