fenclonine has been researched along with Multiple Organ Failure in 1 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Multiple Organ Failure: A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Zymosan-induced multiple organ dysfunction syndrome (MODS) is a multifactorial pathology that involves the deterioration of function of several organs." | 1.42 | Role of Serotonin in MODS: Deficiency of Serotonin Protects Against Zymosan-Induced Multiple Organ Failure in Mice. ( Huang, Z; Liu, C; Liu, S; Liu, Y; Pang, Q; Song, S; Wu, Q; Zhang, J; Zhang, R, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, J | 1 |
| Pang, Q | 1 |
| Song, S | 1 |
| Zhang, R | 1 |
| Liu, S | 1 |
| Huang, Z | 1 |
| Wu, Q | 1 |
| Liu, Y | 1 |
| Liu, C | 1 |
1 other study available for fenclonine and Multiple Organ Failure
| Article | Year |
|---|---|
Role of Serotonin in MODS: Deficiency of Serotonin Protects Against Zymosan-Induced Multiple Organ Failure in Mice.
Topics: 5-Hydroxytryptophan; Animals; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Fenclonine; Male | 2015 |