fenclonine has been researched along with Memory Disorders in 4 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using the kainic acid model of epilepsy in rats, we tested the effects of serotonin depletion on (1) susceptibility to acute seizures, (2) development of spontaneous recurrent seizures and (3) behavioral and neuroanatomical sequelae of kainic acid treatment." | 3.85 | Serotonin depletion increases seizure susceptibility and worsens neuropathological outcomes in kainate model of epilepsy. ( Brazete, CS; Lukoyanov, NV; Luz, LL; Maia, GH; Soares, JI, 2017) |
| "Vortioxetine (VOR) is a multimodal antidepressant drug with pro-cognitive actions in animal models and MDD patients." | 1.56 | Sub-chronic vortioxetine (but not escitalopram) normalizes brain rhythm alterations and memory deficits induced by serotonin depletion in rats. ( Artigas, F; Celada, P; Riga, MS; Sanchez, C, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Riga, MS | 1 |
| Sanchez, C | 1 |
| Celada, P | 1 |
| Artigas, F | 1 |
| Maia, GH | 1 |
| Brazete, CS | 1 |
| Soares, JI | 1 |
| Luz, LL | 1 |
| Lukoyanov, NV | 1 |
| Takahata, K | 1 |
| Minami, A | 1 |
| Kusumoto, H | 1 |
| Shimazu, S | 1 |
| Yoneda, F | 1 |
| Kenton, L | 1 |
| Boon, F | 1 |
| Cain, DP | 1 |
4 other studies available for fenclonine and Memory Disorders
| Article | Year |
|---|---|
Sub-chronic vortioxetine (but not escitalopram) normalizes brain rhythm alterations and memory deficits induced by serotonin depletion in rats.
Topics: Animals; Antidepressive Agents, Second-Generation; Brain; Circadian Rhythm; Citalopram; Fenclonine; | 2020 |
Serotonin depletion increases seizure susceptibility and worsens neuropathological outcomes in kainate model of epilepsy.
Topics: Animals; Disease Models, Animal; Disease Susceptibility; Epilepsy; Fenclonine; Hippocampus; Kainic A | 2017 |
Effects of selegiline alone or with donepezil on memory impairment in rats.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Aziridines; Behavior, Animal; Choline; Cholines | 2005 |
Combined but not individual administration of beta-adrenergic and serotonergic antagonists impairs water maze acquisition in the rat.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relation | 2008 |