fenclonine has been researched along with Magnesium Deficiency in 3 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Magnesium Deficiency: A nutritional condition produced by a deficiency of magnesium in the diet, characterized by anorexia, nausea, vomiting, lethargy, and weakness. Symptoms are paresthesias, muscle cramps, irritability, decreased attention span, and mental confusion, possibly requiring months to appear. Deficiency of body magnesium can exist even when serum values are normal. In addition, magnesium deficiency may be organ-selective, since certain tissues become deficient before others. (Harrison's Principles of Internal Medicine, 12th ed, p1936)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of our study was to analyse the possible implication of the serotoninergic system in the pathophysiology and the lethality of audiogenic seizures induced by magnesium deficiency, either by decreasing cerebral serotonin (5-HT) levels (p-chlorophenylalanine) or by increasing 5-HT levels in the brain (5-hydroxytryptophan, L-tryptophan, nialamide, fluoxetine)." | 3.69 | Effect of various serotoninergically induced manipulations on audiogenic seizures in magnesium-deficient mice. ( Bac, P; Binet, P; Dewulf, C; Durlach, J; Herrenknecht, C; Pages, N, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bac, P | 1 |
| Pages, N | 1 |
| Herrenknecht, C | 1 |
| Dewulf, C | 1 |
| Binet, P | 1 |
| Durlach, J | 1 |
| Depoortere, H | 1 |
| Francon, D | 1 |
| Granger, P | 1 |
| Terzano, MG | 1 |
| Alexander, GJ | 1 |
| Kopeloff, LM | 1 |
3 other studies available for fenclonine and Magnesium Deficiency
| Article | Year |
|---|---|
Effect of various serotoninergically induced manipulations on audiogenic seizures in magnesium-deficient mice.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Analysis of Variance; Animals; Brain; Fenclonine; Fluoxet | 1994 |
Evaluation of the stability and quality of sleep using Hjorth's descriptors.
Topics: Animals; Electroencephalography; Fenclonine; Humans; Ibotenic Acid; Magnesium Deficiency; Male; Olfa | 1993 |
Anticonvulsive effect of p-chlorophenylalanine in mice on a low magnesium diet.
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Behavior, Animal; Fenclonine; Magnesium Deficiency; | 1978 |