fenclonine has been researched along with Liver Neoplasms in 8 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenylalanine hydroxylase in Reuber H4 hepatoma cell cultures can be rapidly inactivated by the addition of epinephrine, norepinephrine, dopamine, or 3,4-dihydroxyphenylalanine, in order of decreasing effectiveness, to the culture medium." | 1.26 | Reversible inactivation of phenylalanine hydroxylase by catecholamines in cultured hepatoma cells. ( Miller, MR; Shiman, R, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rasenack, U | 1 |
| Caspary, W | 1 |
| Spann, JL | 1 |
| Van Wormer, D | 1 |
| Sandlin, ME | 1 |
| Miller, MR | 3 |
| Shiman, R | 3 |
| McClure, D | 2 |
| Gillett, DJ | 1 |
| Smith, RC | 1 |
| Feldman, JM | 1 |
| Plonk, JW | 1 |
| Cornette, JC | 1 |
| von Studnitz, W | 1 |
8 other studies available for fenclonine and Liver Neoplasms
| Article | Year |
|---|---|
[Therapy of carcinoid and the carcinoid syndrome].
Topics: Aminocaproic Acid; Aprotinin; Carcinoma, Squamous Cell; Cyproheptadine; Doxorubicin; Embolization, T | 1983 |
Malignant carcinoid syndrome: two case reports.
Topics: Aged; Female; Fenclonine; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Malignant Carcinoid S | 1980 |
Reversible inactivation of phenylalanine hydroxylase by catecholamines in cultured hepatoma cells.
Topics: Carcinoma, Hepatocellular; Catecholamines; Cell Line; Dihydroxyphenylalanine; Dopamine; Epinephrine; | 1976 |
Mechanism of inactivation of phenylalanine hydroxylase by p-chlorophenylalanine in hepatome cells in culture. Two possible models.
Topics: Animals; Antigens; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Fenclonine; Isoenzymes; Kine | 1976 |
p-Chlorphenylalanine effect on phenylalanine hydroxylase in hepatoma cells in culture.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Fenclonine; Hydrocortisone; Kinetics; L-Lactate | 1975 |
Treatment of the carcinoid syndrome by hemihepatectomy and radical excision of the primary lesion.
Topics: Aged; Cyproheptadine; Diarrhea; Fenclonine; Heart Valve Diseases; Hepatectomy; Humans; Hydroxyindole | 1974 |
Serum prostaglandin F-2 alpha concentration in the carcinoid syndrome.
Topics: Aged; Bronchial Neoplasms; Carcinoid Tumor; Female; Fenclonine; Humans; Hydroxyindoleacetic Acid; In | 1974 |
[Proceedings: Tryptophan hydroxylase inhibition as therapy for carcinoid tumors].
Topics: Carcinoid Heart Disease; Carcinoid Tumor; Constipation; Diarrhea; Eosinophilia; Fenclonine; Humans; | 1972 |