fenclonine has been researched along with Irritable Bowel Syndrome in 2 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Irritable Bowel Syndrome: A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shao, YY | 1 |
| Huang, J | 1 |
| Ma, YR | 1 |
| Han, M | 1 |
| Ma, K | 1 |
| Qin, HY | 1 |
| Rao, Z | 1 |
| Wu, XA | 1 |
| Hirata, T | 1 |
| Keto, Y | 1 |
| Yamano, M | 1 |
| Yokoyama, T | 1 |
| Sengoku, T | 1 |
| Seki, N | 1 |
2 other studies available for fenclonine and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Serum serotonin reduced the expression of hepatic transporter Mrp2 and P-gp via regulating nuclear receptor CAR in PI-IBS rats.
Topics: 5-Hydroxytryptophan; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding C | 2015 |
Inhibitory effect of ramosetron on corticotropin releasing factor- and soybean oil-induced delays in gastric emptying in rats.
Topics: Animals; Antidiarrheals; Benzamides; Benzimidazoles; Benzyl Compounds; Biguanides; Corticotropin-Rel | 2012 |