fenclonine has been researched along with Inflammation in 4 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goeden, N | 1 |
| Velasquez, J | 1 |
| Arnold, KA | 1 |
| Chan, Y | 1 |
| Lund, BT | 1 |
| Anderson, GM | 1 |
| Bonnin, A | 1 |
| Eto, K | 1 |
| Kim, SK | 1 |
| Nabekura, J | 1 |
| Ishibashi, H | 1 |
| León-Ponte, M | 1 |
| Ahern, GP | 1 |
| O'Connell, PJ | 1 |
| Siegel, DM | 1 |
| Giri, SN | 1 |
| Scheinholtz, RM | 1 |
| Schwartz, LW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Investigating Serotonin Signalling in IBD Patients[NCT01650311] | 60 participants (Anticipated) | Observational | 2012-07-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for fenclonine and Inflammation
| Article | Year |
|---|---|
Maternal Inflammation Disrupts Fetal Neurodevelopment via Increased Placental Output of Serotonin to the Fetal Brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Cytokines; Disease Models, Animal; Female; Fenclonine; Fetal De | 2016 |
Taltirelin, a thyrotropin-releasing hormone analog, alleviates mechanical allodynia through activation of descending monoaminergic neurons in persistent inflammatory pain.
Topics: Adrenergic Agents; Animals; Biogenic Monoamines; Disease Models, Animal; Dose-Response Relationship, | 2011 |
Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor.
Topics: Animals; Autocrine Communication; Cells, Cultured; Enzyme Activation; Fenclonine; Gene Expression Re | 2007 |
Characteristics and effect of antiinflammatory drugs on adriamycin-induced inflammation in the mouse paw.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Capillary Permeability; Diphenhydramine; Doxorubicin; Fe | 1980 |