fenclonine has been researched along with Idiopathic Parkinson Disease in 5 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lebsanft, HB | 1 |
| Mayerhofer, A | 1 |
| Kovar, KA | 1 |
| Schmidt, WJ | 1 |
| Chase, TN | 2 |
| Van Woert, MH | 1 |
| Ambani, LM | 1 |
| Levine, RJ | 1 |
| Garelis, E | 1 |
| Young, SN | 1 |
| Lal, S | 1 |
| Sourkes, TL | 1 |
2 reviews available for fenclonine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies.
Topics: Animals; Biological Transport, Active; Brain; Cats; Cerebral Ventricles; Cerebrospinal Fluid; Choroi | 1974 |
Serotonergic mechanisms and extrapyramidal function in man.
Topics: 5-Hydroxytryptophan; Carbidopa; Cerebellar Diseases; Creutzfeldt-Jakob Syndrome; Down Syndrome; Extr | 1974 |
1 trial available for fenclonine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Clinical effects of para-chlorophenylalanine in Parkinson's disease.
Topics: Aged; Benztropine; Brain; Clinical Trials as Topic; Depression; Dihydroxyphenylalanine; Evaluation S | 1972 |
2 other studies available for fenclonine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Is the Ecstasy-induced ipsilateral rotation in 6-hydroxydopamine unilaterally lesioned rats dopamine independent?
Topics: 3,4-Methylenedioxyamphetamine; Adrenergic Agents; Animals; Apomorphine; Behavior, Animal; Citalopram | 2003 |
Serotonergic mechanisms in Parkinson's disease.
Topics: Aged; Brain; Female; Fenclonine; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Parkinson Dise | 1972 |