fenclonine has been researched along with Hyperventilation in 3 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Hyperventilation: A pulmonary ventilation rate faster than is metabolically necessary for the exchange of gases. It is the result of an increased frequency of breathing, an increased tidal volume, or a combination of both. It causes an excess intake of oxygen and the blowing off of carbon dioxide.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In awake, unrestrained, intact rats, reserpine, para-chlorophenylalanine, 6-fluorotryptophan, and para-chloroamphetamine depleted whole brain serotonin and produced a substantial and sustained hyperventilation as evidenced by a 5--9 torr drop in PaCO2." | 3.66 | Serotonin and the control of ventilation in awake rats. ( Dempsey, JA; McCrimmon, DR; Olson, EB, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Annerbrink, K | 1 |
| Olsson, M | 1 |
| Melchior, LK | 1 |
| Hedner, J | 1 |
| Eriksson, E | 1 |
| Olson, EB | 2 |
| Dempsey, JA | 1 |
| McCrimmon, DR | 1 |
3 other studies available for fenclonine and Hyperventilation
| Article | Year |
|---|---|
Serotonin depletion increases respiratory variability in freely moving rats: implications for panic disorder.
Topics: Analysis of Variance; Animals; Carbon Dioxide; Fenclonine; Hyperventilation; Male; Plethysmography; | 2003 |
Serotonin and the control of ventilation in awake rats.
Topics: 5,7-Dihydroxytryptamine; Animals; Brain; Dopamine; Fenclonine; Hyperventilation; Male; Methyltyrosin | 1979 |
Ventilatory adaptation to hypoxia occurs in serotonin-depleted rats.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Blood Gas Analysis; Fenclonine; Hyperventi | 1987 |