fenclonine has been researched along with Hyperactivity, Motor in 11 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The hyperactivity and hyperpyrexia produced by L-tryptophan in rats treated with a monoamine oxidase inhibitor was inhibited by chlorpromazine." | 3.65 | Inhibitory effect of chlorpromazine on the syndrome of hyperactivity produced by L-tryptophan or 5-methoxy-N,N-dimethyltryptamine in rats treated with a monoamine oxidase inhibitor. ( Grahame-Smith, DG, 1971) |
| " Following chronic administration of clenbuterol (5 mg/kg daily for 14 days), a procedure resulting in down-regulation of central beta-adrenoceptors, a larger dose of clenbuterol was necessary to enhance the quipazine-induced hyperactivity, suggesting that the mechanism of enhancement involved central post-synaptic beta-adrenoceptors." | 1.27 | Studies on the mechanisms by which clenbuterol, a beta-adrenoceptor agonist, enhances 5-HT-mediated behaviour and increases metabolism of 5-HT in the brain of the rat. ( Cowen, PJ; Deakin, JF; Grahame-Smith, DG; Green, AR; Heal, DJ; Nimgaonkar, VL, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maximino, C | 1 |
| Puty, B | 1 |
| Benzecry, R | 1 |
| Araújo, J | 1 |
| Lima, MG | 1 |
| de Jesus Oliveira Batista, E | 1 |
| Renata de Matos Oliveira, K | 1 |
| Crespo-Lopez, ME | 1 |
| Herculano, AM | 1 |
| Nimgaonkar, VL | 1 |
| Green, AR | 1 |
| Cowen, PJ | 1 |
| Heal, DJ | 1 |
| Grahame-Smith, DG | 3 |
| Deakin, JF | 1 |
| Fulton, TR | 1 |
| Triano, T | 1 |
| Rabe, A | 1 |
| Loo, YH | 1 |
| Cools, AR | 1 |
| Poitou, P | 1 |
| Boulu, R | 1 |
| Bohuon, C | 1 |
| Brase, DA | 1 |
| Loh, HH | 1 |
| Jacobs, BL | 1 |
| Trimbach, C | 1 |
| Eubanks, EE | 1 |
| Trulson, M | 1 |
| Benkert, O | 1 |
| Köhler, B | 1 |
| Sassin, JF | 1 |
| Taub, S | 1 |
| Weitzman, ED | 1 |
11 other studies available for fenclonine and Hyperactivity, Motor
| Article | Year |
|---|---|
Role of serotonin in zebrafish (Danio rerio) anxiety: relationship with serotonin levels and effect of buspirone, WAY 100635, SB 224289, fluoxetine and para-chlorophenylalanine (pCPA) in two behavioral models.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Brain; Buspirone; Disease Models, Animal; D | 2013 |
Studies on the mechanisms by which clenbuterol, a beta-adrenoceptor agonist, enhances 5-HT-mediated behaviour and increases metabolism of 5-HT in the brain of the rat.
Topics: Animals; Behavior, Animal; Brain; Carbidopa; Clenbuterol; Ethanolamines; Fenclonine; Humans; Hydroxy | 1983 |
Phenylacetate and the enduring behavioral deficit in experimental phenylketonuria.
Topics: Animals; Behavior, Animal; Body Weight; Escape Reaction; Female; Fenclonine; Humans; Hyperkinesis; M | 1980 |
Serotonin: a behaviorally active compound in the caudate nucleus of cats.
Topics: Animals; Athetosis; Autonomic Agents; Behavior, Animal; Carbachol; Cats; Caudate Nucleus; Compulsive | 1973 |
Effect of lithium and other drugs on the amphetamine chlordiazeposice hyperactivity in mice.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Bipolar Disorder; Brain Chemistry; Chlordiazepoxide; Dise | 1975 |
Possible role of 5-hydroxyptamine in minimal brain dysfunction.
Topics: Amphetamine; Animal Nutritional Physiological Phenomena; Animals; Attention Deficit Disorder with Hy | 1975 |
Hippocampal mediation of raphe lesion- and PCPA-induced hyperactivity in the rat.
Topics: Animals; Brain Mapping; Fenclonine; Hippocampus; Humans; Hyperkinesis; Hypophysectomy; Locomotion; N | 1975 |
Studies in vivo on the relationship between brain tryptophan, brain 5-HT synthesis and hyperactivity in rats treated with a monoamine oxidase inhibitor and L-tryptophan.
Topics: 5-Hydroxytryptophan; Amines; Amino Acids; Animals; Brain Chemistry; Carboxy-Lyases; Dopamine; Fenclo | 1971 |
Intrahypothalamic and intrastriatal dopamine and norepinephrine injections in relation to motor hyperactivity in rats.
Topics: Animals; Brain; Corpus Striatum; Dopamine; Fenclonine; Humans; Hyperkinesis; Hypothalamus; Injection | 1972 |
Inhibitory effect of chlorpromazine on the syndrome of hyperactivity produced by L-tryptophan or 5-methoxy-N,N-dimethyltryptamine in rats treated with a monoamine oxidase inhibitor.
Topics: Animals; Brain; Chlorpromazine; Drug Synergism; Fenclonine; Fever; Humans; Hyperkinesis; Male; Monoa | 1971 |
Hyperkinesia and changes in behavior produced in normal monkeys by L-dopa.
Topics: Animals; Apomorphine; Behavior, Animal; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Fe | 1972 |