fenclonine has been researched along with Headache in 6 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Parachlorophenylalanine chronic administration in migraine-headache sufferers lowered the pain threshold so far as to provoke (in 20% of cases) spontaneous pains in the trunk, legs and arms." | 5.25 | 5-Hydroxytryptamine and pain modulation in man: a clinical pharmacological approach with tryptophan and parachlorophenylalanine. ( Anselmi, B; Del Bene, E; Galli, P; Sicuteri, F, 1975) |
| " Parachlorophenylalanine chronic administration in migraine-headache sufferers lowered the pain threshold so far as to provoke (in 20% of cases) spontaneous pains in the trunk, legs and arms." | 1.25 | 5-Hydroxytryptamine and pain modulation in man: a clinical pharmacological approach with tryptophan and parachlorophenylalanine. ( Anselmi, B; Del Bene, E; Galli, P; Sicuteri, F, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sicuteri, F | 6 |
| Del Bene, E | 2 |
| Fonda, C | 1 |
| Anselmi, B | 3 |
| Galli, P | 1 |
| Del Bianco, PL | 2 |
| Franchi, G | 1 |
| Fanciullacci, M | 1 |
1 review available for fenclonine and Headache
| Article | Year |
|---|---|
Sex, migraine and serotonin interrelationships.
Topics: 5-Hydroxytryptophan; Animals; Female; Fenclonine; Headache; Humans; Male; Menstruation; Migraine Dis | 1976 |
1 trial available for fenclonine and Headache
| Article | Year |
|---|---|
Serotonin and sex in man.
Topics: Adult; Aged; Clinical Trials as Topic; Drug Therapy, Combination; Feeding and Eating Disorders; Fema | 1974 |
4 other studies available for fenclonine and Headache
| Article | Year |
|---|---|
5-Hydroxytryptamine and pain modulation in man: a clinical pharmacological approach with tryptophan and parachlorophenylalanine.
Topics: 5-Hydroxytryptophan; Animals; Fenclonine; Headache; Humans; Pain; Serotonin; Tryptophan | 1975 |
Headache as possible expression of deficiency of brain 5-hydroxytryptamine (central denervation supersensitivity).
Topics: Adult; Brain Chemistry; Female; Fenclonine; Headache; Humans; Migraine Disorders; Pain; Serotonin | 1972 |
5-hydroxytryptamine supersensitivity as a new theory of headache and central pain: a clinical pharmacological approach with p-chlorophenylalanine.
Topics: Brain Chemistry; Drug Hypersensitivity; Fenclonine; Headache; Humans; Lysergic Acid Diethylamide; Me | 1973 |
[5-Hydroxytryptamine and physiopathology of pain; on a polyalgic syndrome in the course of therapy with para-chlorophenylalanine].
Topics: Catecholamines; Eosinophilia; Fenclonine; Fever; Headache; Humans; Migraine Disorders; Pain; Seroton | 1972 |