fenclonine has been researched along with Experimental Neoplasms in 5 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenylalanine hydroxylase in Reuber H4 hepatoma cell cultures can be rapidly inactivated by the addition of epinephrine, norepinephrine, dopamine, or 3,4-dihydroxyphenylalanine, in order of decreasing effectiveness, to the culture medium." | 1.26 | Reversible inactivation of phenylalanine hydroxylase by catecholamines in cultured hepatoma cells. ( Miller, MR; Shiman, R, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vinnitskii, VB | 1 |
| Iakimenko, VA | 1 |
| Kelly, CJ | 1 |
| Johnson, TC | 1 |
| Miller, MR | 3 |
| Shiman, R | 3 |
| McClure, D | 2 |
5 other studies available for fenclonine and Experimental Neoplasms
| Article | Year |
|---|---|
[Effect of fenformin, L-DOPA and para-chlorophenylalanine on the immunological reactivity and chemical carcinogenesis in BALB/c mice].
Topics: Animals; Antibody-Producing Cells; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fencloni | 1981 |
Effects of p-chlorophenylalanine and alpha-methylphenylalanine on amino acid uptake and protein synthesis in mouse neuroblastoma cells.
Topics: Amino Acids; Animals; Cell Line; Fenclonine; Mice; Models, Biological; Neoplasms, Experimental; Neur | 1978 |
Reversible inactivation of phenylalanine hydroxylase by catecholamines in cultured hepatoma cells.
Topics: Carcinoma, Hepatocellular; Catecholamines; Cell Line; Dihydroxyphenylalanine; Dopamine; Epinephrine; | 1976 |
Mechanism of inactivation of phenylalanine hydroxylase by p-chlorophenylalanine in hepatome cells in culture. Two possible models.
Topics: Animals; Antigens; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Fenclonine; Isoenzymes; Kine | 1976 |
p-Chlorphenylalanine effect on phenylalanine hydroxylase in hepatoma cells in culture.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Fenclonine; Hydrocortisone; Kinetics; L-Lactate | 1975 |