fenclonine has been researched along with Epilepsy, Absence in 2 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bercovici, E | 1 |
| Cortez, MA | 1 |
| Wang, X | 1 |
| Snead, OC | 1 |
| Arushanian, EB | 1 |
| Avakian, RM | 1 |
2 other studies available for fenclonine and Epilepsy, Absence
| Article | Year |
|---|---|
Serotonin depletion attenuates AY-9944-mediated atypical absence seizures.
Topics: Animals; Anticholesteremic Agents; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Ele | 2006 |
[Participation of monoaminergic mechanisms and the striatum in the development of "petit mal" induced by corazole].
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Biogenic Amines; Chlorpromazine; Corpus Striatum; Drug In | 1978 |