fenclonine has been researched along with Edema in 7 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pretreatment with p-chlorophenylalanine, indomethacin, ibuprofen, and nimodipine attenuated the SCEP changes immediately after trauma and resulted in a marked reduction in edema formation, BSCB permeability, and blood flow changes at 5 h." | 3.71 | Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat. ( Sharma, HS; Winkler, T, 2002) |
| "Paw oedema was decreased significantly in PCPA-treated (100 microg/rat, i." | 1.33 | Effects of central and peripheral depletion of serotonergic system on carrageenan-induced paw oedema. ( Garjani, A; Maleki, N; Nayebi, AM, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, HS | 6 |
| Winkler, T | 3 |
| Westman, J | 3 |
| Maleki, N | 1 |
| Nayebi, AM | 1 |
| Garjani, A | 1 |
| Stålberg, E | 2 |
| Badgaiyan, RD | 1 |
| Alm, P | 1 |
| Gordh, T | 1 |
| Nyberg, F | 1 |
| Olsson, Y | 2 |
| Dey, PK | 1 |
7 other studies available for fenclonine and Edema
| Article | Year |
|---|---|
Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Anti-I | 2002 |
Depletion of endogenous serotonin synthesis with p-CPA attenuates upregulation of constitutive isoform of heme oxygenase-2 expression, edema formation and cell injury following a focal trauma to the rat spinal cord.
Topics: Animals; Edema; Fenclonine; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); HSP72 Heat-Shock Prot | 2003 |
Effects of central and peripheral depletion of serotonergic system on carrageenan-induced paw oedema.
Topics: Animals; Carrageenan; Disease Models, Animal; Drug Administration Schedule; Edema; Fenclonine; Hindl | 2005 |
Spinal cord evoked potentials and edema in the pathophysiology of rat spinal cord injury. Involvement of nitric oxide.
Topics: Animals; Diazepam; Edema; Enzyme Inhibitors; Evoked Potentials; Fenclonine; Male; NG-Nitroarginine M | 1998 |
Spinal cord injury induced c-fos expression is reduced by p-CPA, a serotonin synthesis inhibitor. An experimental study using immunohistochemistry in the rat.
Topics: Animals; Edema; Fenclonine; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Seroton | 2000 |
Evaluation of traumatic spinal cord edema using evoked potentials recorded from the spinal epidural space. An experimental study in the rat.
Topics: Animals; Cyproheptadine; Edema; Epidural Space; Evoked Potentials; Fenclonine; Male; Rats; Rats, Inb | 1991 |
Edema formation and cellular alterations following spinal cord injury in the rat and their modification with p-chlorophenylalanine.
Topics: Animals; Edema; Fenclonine; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Serotonin; Spina | 1990 |