fenclonine has been researched along with Disease Models, Animal in 105 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has been reported that fluoxetine, a selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitor, has neuroprotective properties in the lithium-pilocarpine model of status epilepticus (SE) in rats." | 7.83 | Serotonin Depletion Does not Modify the Short-Term Brain Hypometabolism and Hippocampal Neurodegeneration Induced by the Lithium-Pilocarpine Model of Status Epilepticus in Rats. ( Bascuñana, P; de Cristóbal, J; Delgado, M; Fernández de la Rosa, R; García-García, L; Pozo, MA; Shiha, AA, 2016) |
| " Using the kainic acid model of epilepsy in rats, we tested the effects of serotonin depletion on (1) susceptibility to acute seizures, (2) development of spontaneous recurrent seizures and (3) behavioral and neuroanatomical sequelae of kainic acid treatment." | 3.85 | Serotonin depletion increases seizure susceptibility and worsens neuropathological outcomes in kainate model of epilepsy. ( Brazete, CS; Lukoyanov, NV; Luz, LL; Maia, GH; Soares, JI, 2017) |
| "It has been reported that fluoxetine, a selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitor, has neuroprotective properties in the lithium-pilocarpine model of status epilepticus (SE) in rats." | 3.83 | Serotonin Depletion Does not Modify the Short-Term Brain Hypometabolism and Hippocampal Neurodegeneration Induced by the Lithium-Pilocarpine Model of Status Epilepticus in Rats. ( Bascuñana, P; de Cristóbal, J; Delgado, M; Fernández de la Rosa, R; García-García, L; Pozo, MA; Shiha, AA, 2016) |
| "We investigated whether tipepidine exerts an antidepressant-like effect in the forced swimming test in adrenocorticotropic hormone (ACTH)-treated rats, which is known as a treatment-resistant depression model, and we studied the pharmacological mechanisms of the effects of tipepidine." | 3.83 | Tipepidine, a non-narcotic antitussive, exerts an antidepressant-like effect in the forced swimming test in adrenocorticotropic hormone-treated rats. ( Honda, S; Kawaura, K; Ogata, Y; Shirasaki, T; Soeda, F; Takahama, K, 2016) |
| " However, single treatment with XBXT-2 had no effect on yohimbine toxicity and high dose of apomorphine-induced hypothermia in mice." | 3.74 | Role for serotonin in the antidepressant-like effect of a flavonoid extract of Xiaobuxin-Tang. ( An, L; Li, YF; Liu, XM; Yu, NJ; Yuan, L; Zhang, YZ; Zhao, N, 2008) |
| "The effect of inositol as an antidepressant was previously demonstrated in both animal models of depression-like behavior and in clinical trials." | 3.71 | The antidepressant activity of inositol in the forced swim test involves 5-HT(2) receptors. ( Belmaker, RH; Bourin, M; Clenet, F; Einat, H; Shaldubina, A, 2001) |
| " To investigate this phenomenon as a possible animal model of obsessive-compulsive disorder (OCD), rats were treated for 5 weeks with fluoxetine, an antidepressant that relieves OCD symptoms in humans (5 mg/kg, 2." | 3.69 | Effects of serotonergic agents on food-restriction-induced hyperactivity. ( Altemus, M; Galliven, E; Glowa, JR; Leong, YM; Murphy, DL, 1996) |
| "Mechanical and thermal hyperalgesia were reduced significantly with enriched diet and/or companionship." | 1.62 | Diet and companionship modulate pain via a serotonergic mechanism. ( Badgaiyan, RD; Gupta, K; Jarrett, S; Palzer, EF; Sagi, V; Tran, H, 2021) |
| "To reveal the influence of insomnia on the levels of the neurotransmitters including serotonin (5-HT), glutamic acid (Glu), γ-aminobutyric acid (GABA), noradrenaline (NE) and dopamine (DA), and to study the role of ZSS aqueous extract in the treatment of insomnia, an UPLC-ESI- MS/MS method was developed and validated for simultaneous determination of five neurotransmitters in the rat brain." | 1.51 | Determination of five neurotransmitters in the rat brain for the study of the hypnotic effects of Ziziphi Spinosae Semen aqueous extract on insomnia rat model by UPLC-MS/MS. ( DU, CH; DU, HZ; Li, AP; Li, Q; Pei, XP; Qin, XM; Shen, CX; Yan, Y, 2019) |
| "Zymosan-induced multiple organ dysfunction syndrome (MODS) is a multifactorial pathology that involves the deterioration of function of several organs." | 1.42 | Role of Serotonin in MODS: Deficiency of Serotonin Protects Against Zymosan-Induced Multiple Organ Failure in Mice. ( Huang, Z; Liu, C; Liu, S; Liu, Y; Pang, Q; Song, S; Wu, Q; Zhang, J; Zhang, R, 2015) |
| " Multiple dosing may improve the absorption of JTW in insomnic rats, which will increase the bioavailability and bring into active role in therapeutical effect." | 1.40 | Integrated pharmacokinetics of five protoberberine-type alkaloids in normal and insomnic rats after single and multiple oral administration of Jiao-Tai-Wan. ( Cai, H; He, W; Hou, W; Liao, Q; Liu, G; Sun, X; Xie, Z; Zhang, P, 2014) |
| " Although monoamine oxidase activity remained unaltered by oleanolic acid, chronic administration of oleanolic acid augmented hippocampal BDNF level." | 1.40 | Plurality of anxiety and depression alteration mechanism by oleanolic acid. ( Costa, EA; Da Rocha, FF; Fajemiroye, JO; Florentino, IF; Galdino, PM; Ghedini, PC; Polepally, PR; Zjawiony, JK, 2014) |
| "The model of insomnia rats were established by PCPA intraperitoneal injection, after the modeling, all the therapeutic group were treated with corresponding drug for one week." | 1.39 | [Effects of extracts from ziziphi spinosae semen and schisandrae chinensis fructus on amino acid neurotransmitter in rats with insomnia induced by PCPA]. ( Chen, JF; Gao, JR; Ji, WB; Jiang, H, 2013) |
| "Ankle joint mobilization decreased mechanical hyperalgesia, and this effect was reversed by pretreatment of the animals with caffeine given by intraperitoneal, intraplantar, and intrathecal routes." | 1.39 | Ankle joint mobilization affects postoperative pain through peripheral and central adenosine A1 receptors. ( Cidral-Filho, FJ; Martins, DF; Mazzardo-Martins, L; Santos, AR; Stramosk, J, 2013) |
| "Carvacrol (cvc) was administered orally at single doses of 12." | 1.37 | Antidepressant-like effect of carvacrol (5-Isopropyl-2-methylphenol) in mice: involvement of dopaminergic system. ( de Sousa, DP; de Sousa, FC; de Vasconcelos, SM; Fonteles, MM; Macedo, DS; Melo, FH; Moura, BA; Viana, GS, 2011) |
| "Other epilepsies or autism often ensue especially in symptomatic IS (SIS)." | 1.36 | A model of symptomatic infantile spasms syndrome. ( Betancourth, D; Chudomelova, L; Galanopoulou, AS; Moshé, SL; Raffo, E; Scantlebury, MH, 2010) |
| "Paw oedema was decreased significantly in PCPA-treated (100 microg/rat, i." | 1.33 | Effects of central and peripheral depletion of serotonergic system on carrageenan-induced paw oedema. ( Garjani, A; Maleki, N; Nayebi, AM, 2005) |
| "Prolonged hyperalgesia was induced by OVX, and the antinociceptive effect of ECT was proved because peripherally and repeatedly administered ECT improved hyperalgesia." | 1.31 | Analgesic mechanism of calcitonin. ( Yoshimura, M, 2000) |
| "In rats with cerebral ischemia, idebenone (10 mg/kg, i." | 1.28 | Effects of idebenone on metabolism of monoamines and cyclic AMP formation in rats. ( Kakihana, M; Nagai, Y; Nagaoka, A; Nagawa, Y; Narumi, S; Yamazaki, N, 1989) |
| "Phenylketonuria is a genetic defect that leads to imbecility, if the diagnosis is not made directly after birth." | 1.26 | Phenylketonuria: clinical and experimental considerations revealed by the use of animal models. ( Lane, JD; Neuhoff, V, 1980) |
| "This degree of hyperphenylalaninaemia, persisting for 18h per day throughout a critical period of development, fulfils the primary criterion of a suitable animal model for phenylketonuria." | 1.26 | The regulation of phenylalanine hydroxylase in rat tissues in vivo. The maintenance of high plasma phenylalanine concentrations in suckling rats: a model for phenylketonuria. ( Delvalle, JA; Greengard, O, 1976) |
| "hipp seizure developed into motor seizure after establishing secondary epileptogenesis in AM and globys paliidus." | 1.26 | A study of psychomotor epilepsy with "kindled" cat preparations. ( Sato, M, 1976) |
| "These manifestations of phenylketonuria were reproduced in rats treated with phenylacetate in amounts approximating those likely to be produced in phenylketonuria." | 1.26 | Myelin deficiency in experimental phenylketonuria: contribution of the aromatic acid metabolites of phenylalanine. ( Loo, YH; Scotto, J; Wisniewski, HM, 1978) |
| "Model phenylketonuria was induced in albino rats by injecting (at 1-20 days of age) and feeding (at 21-80 days) L-phenylalanine and D-L-para-chloro-phenylalanine." | 1.25 | Model phenylketonuria (PKU) in the albino rat: behaviroal, biochemical, and neuroanatomical effects. ( Brown, WJ; Copenhaver, JH; Gunter, R; Schalock, RL, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (40.00) | 18.7374 |
| 1990's | 2 (1.90) | 18.2507 |
| 2000's | 19 (18.10) | 29.6817 |
| 2010's | 38 (36.19) | 24.3611 |
| 2020's | 4 (3.81) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Yan, Y | 1 |
| Li, Q | 1 |
| DU, HZ | 1 |
| Shen, CX | 1 |
| Li, AP | 1 |
| Pei, XP | 1 |
| DU, CH | 1 |
| Qin, XM | 1 |
| Sahbaie, P | 1 |
| Irvine, KA | 1 |
| Liang, DY | 1 |
| Shi, X | 1 |
| Clark, JD | 1 |
| Xu, Y | 1 |
| Li, X | 1 |
| Man, D | 1 |
| Su, X | 1 |
| A, G | 1 |
| Tran, H | 1 |
| Sagi, V | 1 |
| Jarrett, S | 1 |
| Palzer, EF | 1 |
| Badgaiyan, RD | 1 |
| Gupta, K | 1 |
| Hagsäter, SM | 1 |
| Pettersson, R | 1 |
| Holmäng, A | 1 |
| Eriksson, E | 2 |
| Bai, Y | 2 |
| Li, ZX | 1 |
| Wang, HL | 2 |
| Lian, GC | 2 |
| Wang, Y | 2 |
| Maia, GH | 1 |
| Brazete, CS | 1 |
| Soares, JI | 1 |
| Luz, LL | 1 |
| Lukoyanov, NV | 1 |
| Gannon, BM | 1 |
| Williamson, A | 1 |
| Rice, KC | 1 |
| Fantegrossi, WE | 1 |
| Zhang, K | 1 |
| Dong, C | 1 |
| Fujita, Y | 1 |
| Fujita, A | 1 |
| Hashimoto, K | 1 |
| Suzuki, T | 1 |
| Shimizu, T | 1 |
| Kwon, J | 1 |
| Takaoka, E | 1 |
| Yoshikawa, S | 1 |
| Sumino, Y | 1 |
| Kitta, T | 1 |
| Miyazato, M | 1 |
| Miyake, H | 1 |
| Yoshimura, N | 1 |
| Amoateng, P | 1 |
| Kukuia, KKE | 1 |
| Mensah, JA | 1 |
| Osei-Safo, D | 1 |
| Adjei, S | 1 |
| Eklemet, AA | 1 |
| Vinyo, EA | 1 |
| Karikari, TK | 1 |
| Silva, EF | 1 |
| Silva, AI | 1 |
| Asth, L | 1 |
| Souza, LS | 1 |
| Zaveri, NT | 1 |
| Guerrini, R | 1 |
| Calo', G | 1 |
| Ruzza, C | 1 |
| Gavioli, EC | 1 |
| Maximino, C | 1 |
| Puty, B | 1 |
| Benzecry, R | 1 |
| Araújo, J | 1 |
| Lima, MG | 1 |
| de Jesus Oliveira Batista, E | 1 |
| Renata de Matos Oliveira, K | 1 |
| Crespo-Lopez, ME | 1 |
| Herculano, AM | 1 |
| Lin, FJ | 1 |
| Yang, XS | 1 |
| Yang, D | 1 |
| Zou, YQ | 1 |
| Wang, HM | 1 |
| Liu, M | 1 |
| Zhang, XH | 1 |
| Kang, J | 1 |
| Gao, JR | 1 |
| Ji, WB | 1 |
| Jiang, H | 1 |
| Chen, JF | 1 |
| He, W | 1 |
| Liu, G | 1 |
| Cai, H | 1 |
| Sun, X | 1 |
| Hou, W | 1 |
| Zhang, P | 1 |
| Xie, Z | 1 |
| Liao, Q | 1 |
| Fajemiroye, JO | 1 |
| Galdino, PM | 1 |
| Florentino, IF | 1 |
| Da Rocha, FF | 1 |
| Ghedini, PC | 1 |
| Polepally, PR | 1 |
| Zjawiony, JK | 1 |
| Costa, EA | 1 |
| Udo, H | 1 |
| Hamasu, K | 1 |
| Furuse, M | 1 |
| Sugiyama, H | 1 |
| Zhang, J | 1 |
| Pang, Q | 1 |
| Song, S | 1 |
| Zhang, R | 1 |
| Liu, S | 1 |
| Huang, Z | 1 |
| Wu, Q | 1 |
| Liu, Y | 1 |
| Liu, C | 1 |
| Shao, YY | 1 |
| Huang, J | 1 |
| Ma, YR | 1 |
| Han, M | 1 |
| Ma, K | 1 |
| Qin, HY | 1 |
| Rao, Z | 1 |
| Wu, XA | 1 |
| García-García, L | 1 |
| Shiha, AA | 1 |
| Bascuñana, P | 1 |
| de Cristóbal, J | 1 |
| Fernández de la Rosa, R | 1 |
| Delgado, M | 1 |
| Pozo, MA | 1 |
| Martins, DF | 2 |
| Emer, AA | 1 |
| Batisti, AP | 1 |
| Donatello, N | 1 |
| Carlesso, MG | 1 |
| Mazzardo-Martins, L | 2 |
| Venzke, D | 1 |
| Micke, GA | 1 |
| Pizzolatti, MG | 1 |
| Piovezan, AP | 1 |
| dos Santos, AR | 1 |
| Nikaido, Y | 1 |
| Yamada, J | 1 |
| Migita, K | 1 |
| Shiba, Y | 1 |
| Furukawa, T | 1 |
| Nakashima, T | 1 |
| Ueno, S | 1 |
| Kawaura, K | 1 |
| Ogata, Y | 1 |
| Honda, S | 1 |
| Soeda, F | 1 |
| Shirasaki, T | 1 |
| Takahama, K | 1 |
| Näslund, J | 1 |
| Studer, E | 1 |
| Johansson, E | 1 |
| Goeden, N | 1 |
| Velasquez, J | 1 |
| Arnold, KA | 1 |
| Chan, Y | 1 |
| Lund, BT | 1 |
| Anderson, GM | 1 |
| Bonnin, A | 1 |
| Sant'Ana, AB | 1 |
| Weffort, LF | 1 |
| de Oliveira Sergio, T | 1 |
| Gomes, RC | 1 |
| Frias, AT | 1 |
| Matthiesen, M | 1 |
| Vilela-Costa, HH | 1 |
| Yamashita, PS | 1 |
| Vasconcelos, AT | 1 |
| de Bortoli, V | 1 |
| Del-Ben, CM | 1 |
| Zangrossi, H | 1 |
| Sasaki-Hamada, S | 1 |
| Suzuki, A | 1 |
| Ueda, Y | 1 |
| Matsumoto, K | 1 |
| Oka, JI | 1 |
| Stracke, J | 1 |
| Otten, W | 1 |
| Tuchscherer, A | 1 |
| Puppe, B | 1 |
| Düpjan, S | 1 |
| Ohno, Y | 2 |
| Shimizu, S | 2 |
| Imaki, J | 2 |
| Ishihara, S | 2 |
| Sofue, N | 2 |
| Sasa, M | 2 |
| Kawai, Y | 2 |
| Takayama, B | 1 |
| Kikuchi, S | 1 |
| Konno, S | 1 |
| Sekiguchi, M | 1 |
| Sinha, RK | 1 |
| Aggarwal, Y | 1 |
| Licht, CL | 1 |
| Marcussen, AB | 1 |
| Wegener, G | 2 |
| Overstreet, DH | 1 |
| Aznar, S | 1 |
| Knudsen, GM | 1 |
| Kwon, S | 1 |
| Lee, B | 1 |
| Kim, M | 1 |
| Lee, H | 1 |
| Park, HJ | 1 |
| Hahm, DH | 1 |
| Scantlebury, MH | 1 |
| Galanopoulou, AS | 1 |
| Chudomelova, L | 1 |
| Raffo, E | 1 |
| Betancourth, D | 1 |
| Moshé, SL | 1 |
| Yi, LT | 1 |
| Li, CF | 1 |
| Zhan, X | 1 |
| Cui, CC | 1 |
| Xiao, F | 1 |
| Zhou, LP | 1 |
| Xie, Y | 1 |
| Melo, FH | 1 |
| Moura, BA | 1 |
| de Sousa, DP | 1 |
| de Vasconcelos, SM | 1 |
| Macedo, DS | 1 |
| Fonteles, MM | 1 |
| Viana, GS | 1 |
| de Sousa, FC | 1 |
| Alkam, T | 1 |
| Hiramatsu, M | 1 |
| Mamiya, T | 1 |
| Aoyama, Y | 1 |
| Nitta, A | 1 |
| Yamada, K | 1 |
| Kim, HC | 1 |
| Nabeshima, T | 1 |
| de Carvalho, RS | 1 |
| Duarte, FS | 1 |
| de Lima, TC | 1 |
| Vines, A | 1 |
| Delattre, AM | 1 |
| Lima, MM | 1 |
| Rodrigues, LS | 1 |
| Suchecki, D | 1 |
| Machado, RB | 1 |
| Tufik, S | 1 |
| Pereira, SI | 1 |
| Zanata, SM | 1 |
| Ferraz, AC | 1 |
| Eto, K | 1 |
| Kim, SK | 1 |
| Nabekura, J | 1 |
| Ishibashi, H | 1 |
| Manna, SS | 1 |
| Umathe, SN | 1 |
| Cidral-Filho, FJ | 1 |
| Stramosk, J | 1 |
| Santos, AR | 2 |
| Marchand, F | 1 |
| Alloui, A | 1 |
| Chapuy, E | 1 |
| Jourdan, D | 1 |
| Pelissier, T | 1 |
| Ardid, D | 1 |
| Hernandez, A | 1 |
| Eschalier, A | 1 |
| Dias Elpo Zomkowski, A | 1 |
| Oscar Rosa, A | 1 |
| Lin, J | 1 |
| Calixto, JB | 1 |
| Lúcia Severo Rodrigues, A | 1 |
| Redrobe, JP | 1 |
| Dumont, Y | 1 |
| Fournier, A | 1 |
| Baker, GB | 1 |
| Quirion, R | 1 |
| Maleki, N | 1 |
| Nayebi, AM | 1 |
| Garjani, A | 1 |
| Bechtholt, AJ | 1 |
| Hill, TE | 1 |
| Lucki, I | 1 |
| Uday, G | 1 |
| Pravinkumar, B | 1 |
| Manish, W | 1 |
| Sudhir, U | 1 |
| Savegnago, L | 1 |
| Jesse, CR | 1 |
| Pinto, LG | 1 |
| Rocha, JB | 1 |
| Nogueira, CW | 1 |
| Zeni, G | 1 |
| Utsu, Y | 1 |
| Shinomiya, K | 1 |
| Tokunaga, S | 1 |
| Ohmori, A | 1 |
| Kamei, C | 1 |
| Dos Santos, JG | 1 |
| Kawano, F | 1 |
| Nishida, MM | 1 |
| Yamamura, Y | 1 |
| Mello, LE | 1 |
| Tabosa, A | 1 |
| Krass, M | 1 |
| Vasar, E | 1 |
| Volke, V | 1 |
| An, L | 1 |
| Zhang, YZ | 1 |
| Yu, NJ | 1 |
| Liu, XM | 1 |
| Zhao, N | 1 |
| Yuan, L | 1 |
| Li, YF | 1 |
| Nakatomi, Y | 1 |
| Yokoyama, C | 1 |
| Kinoshita, S | 1 |
| Masaki, D | 1 |
| Tsuchida, H | 1 |
| Onoe, H | 1 |
| Yoshimoto, K | 1 |
| Fukui, K | 1 |
| Dwivedy, AK | 2 |
| Shah, SN | 3 |
| Chamove, AS | 1 |
| Johnson, RC | 1 |
| Benevenga, NJ | 1 |
| Steele, RD | 1 |
| Walker, RF | 1 |
| Cooper, RL | 1 |
| Timiras, PS | 1 |
| Lane, JD | 2 |
| Schöne, B | 1 |
| Langenbeck, U | 1 |
| Neuhoff, V | 2 |
| Lo, GS | 1 |
| Longenecker, JB | 1 |
| Vorhees, CV | 1 |
| Butcher, RE | 1 |
| Berry, HK | 1 |
| Zanić-Grubisić, T | 1 |
| Lipovac, K | 1 |
| Sharma, SD | 1 |
| Cooley, C | 1 |
| De La Pava, E | 1 |
| Ambrus, CM | 1 |
| Fuchs, V | 1 |
| Coper, H | 1 |
| Whitaker-Azmitia, PM | 1 |
| Borella, A | 1 |
| Raio, N | 1 |
| Altemus, M | 1 |
| Glowa, JR | 1 |
| Galliven, E | 1 |
| Leong, YM | 1 |
| Murphy, DL | 1 |
| Yoshimura, M | 1 |
| Einat, H | 1 |
| Clenet, F | 1 |
| Shaldubina, A | 1 |
| Belmaker, RH | 1 |
| Bourin, M | 1 |
| Murthy, LT | 1 |
| Poitou, P | 1 |
| Boulu, R | 1 |
| Bohuon, C | 1 |
| Avins, L | 1 |
| Guroff, G | 3 |
| Kuwabara, T | 1 |
| Valdivieso, F | 2 |
| Gimenez, C | 2 |
| Mayor, F | 2 |
| Rowe, VD | 1 |
| Fales, HM | 1 |
| Pisano, JJ | 1 |
| Andersen, AE | 2 |
| Antonas, KN | 1 |
| Coulson, WF | 1 |
| Schalock, RL | 3 |
| Brown, WJ | 2 |
| Copenhaver, JH | 3 |
| Gunter, R | 2 |
| Delvalle, JA | 1 |
| Greengard, O | 1 |
| Sato, M | 1 |
| Nĕmecek, S | 1 |
| Petr, R | 1 |
| Suba, P | 1 |
| Rozsíval, V | 1 |
| Dhondt, JL | 2 |
| Farriaux, JP | 2 |
| Schaub, RG | 1 |
| Meyers, KM | 1 |
| Sande, RD | 1 |
| Dautrevaux, M | 1 |
| Biserte, G | 1 |
| Laborit, H | 1 |
| Desplaces, N | 1 |
| Tachiki, KH | 1 |
| Takagi, A | 1 |
| Tateishi, T | 1 |
| Kido, A | 1 |
| Nishiwaki, K | 1 |
| Nakamura, E | 1 |
| Nagayama, H | 1 |
| Takahashi, R | 1 |
| Loo, YH | 1 |
| Scotto, J | 1 |
| Wisniewski, HM | 1 |
| Benavides, J | 1 |
| Sanchez-Rubiales, M | 1 |
| Nagai, Y | 1 |
| Narumi, S | 1 |
| Kakihana, M | 1 |
| Yamazaki, N | 1 |
| Nagaoka, A | 1 |
| Nagawa, Y | 1 |
| Okano, Y | 1 |
| Chow, IZ | 1 |
| Isshiki, G | 1 |
| Inoue, A | 1 |
| Oura, T | 1 |
| Pueschel, SM | 1 |
| Boylan, J | 1 |
| Ellenbogen, R | 1 |
| Lycke, E | 1 |
| Roos, BE | 1 |
| Babington, RG | 1 |
| Wedeking, PW | 1 |
| Masek, K | 1 |
| Rasková, H | 1 |
| Rotta, J | 1 |
| Schalock, R | 1 |
| Carver, MJ | 1 |
| Tourian, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Atlas Cedarwood Essential Oil Aromatherapy on Sleep Quality Among Patients With Coronary Heart Disease: a Randomized Controlled Trial[NCT03830554] | 96 participants (Actual) | Interventional | 2018-07-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for fenclonine and Disease Models, Animal
| Article | Year |
|---|---|
Adverse effects of excessive consumption of amino acids.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Brain; Cattle; Diet; Disease Models, Ani | 1984 |
Progress in experimental phenylketonuria: a critical review.
Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Energy Metabolism; Female; Fenclonine; Glu | 1981 |
Urinary phenylalanine metabolites in preweanling rats treated with p-chlorophenylalanine and phenylalanine.
Topics: Animals; Disease Models, Animal; Fenclonine; Humans; Lactates; Phenylalanine; Phenylketonurias; Phen | 1975 |
102 other studies available for fenclonine and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Determination of five neurotransmitters in the rat brain for the study of the hypnotic effects of Ziziphi Spinosae Semen aqueous extract on insomnia rat model by UPLC-MS/MS.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Fenclonine; Hypnotics | 2019 |
Mild Traumatic Brain Injury Causes Nociceptive Sensitization through Spinal Chemokine Upregulation.
Topics: 5,7-Dihydroxytryptamine; Animals; Benzamides; Brain Injuries, Traumatic; Chemokine CXCL1; Chemokine | 2019 |
iTRAQ-based proteomics analysis on insomnia rats treated with Mongolian medical warm acupuncture.
Topics: Acupuncture Therapy; Animals; Disease Models, Animal; Extracellular Matrix Proteins; Fenclonine; Hum | 2020 |
Diet and companionship modulate pain via a serotonergic mechanism.
Topics: Analgesics, Opioid; Anemia, Sickle Cell; Animals; Chronic Pain; Diet; Disease Models, Animal; Duloxe | 2021 |
Serotonin depletion reduces both acquisition and expression of context-conditioned fear.
Topics: Animals; Anxiety; Behavior, Animal; Conditioning, Psychological; Disease Models, Animal; Fear; Fencl | 2021 |
The protective effects of PCPA against monocrotaline-induced pulmonary arterial hypertension are mediated through the downregulation of NFAT-1 and NF-κB.
Topics: Animals; Disease Models, Animal; Fenclonine; Hypertension, Pulmonary; Male; Monocrotaline; NFATC Tra | 2017 |
Serotonin depletion increases seizure susceptibility and worsens neuropathological outcomes in kainate model of epilepsy.
Topics: Animals; Disease Models, Animal; Disease Susceptibility; Epilepsy; Fenclonine; Hippocampus; Kainic A | 2017 |
Role of monoaminergic systems and ambient temperature in bath salts constituent 3,4-methylenedioxypyrovalerone (MDPV)-elicited hyperthermia and locomotor stimulation in mice.
Topics: alpha-Methyltyrosine; Analysis of Variance; Animals; Benzodioxoles; Biogenic Monoamines; Body Temper | 2018 |
5-Hydroxytryptamine-Independent Antidepressant Actions of (R)-Ketamine in a Chronic Social Defeat Stress Model.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Chromatography, Liquid; Disease Models, Ani | 2018 |
Role of the serotonergic system in urethral continence reflexes during sneezing in rats.
Topics: Animals; Disease Models, Animal; Female; Fenclonine; Piperazines; Pressure; Pyrazines; Rats, Sprague | 2018 |
An extract of Synedrella nodiflora (L) Gaertn exhibits antidepressant properties through monoaminergic mechanisms.
Topics: Animals; Antidepressive Agents; Asteraceae; Behavior, Animal; Depression; Disease Models, Animal; Fe | 2018 |
Nociceptin/orphanin FQ receptor agonists increase aggressiveness in the mouse resident-intruder test.
Topics: Aggression; Agonistic Behavior; Animals; Anxiety; Bipolar Disorder; Carbamazepine; Cycloheptanes; De | 2019 |
Role of serotonin in zebrafish (Danio rerio) anxiety: relationship with serotonin levels and effect of buspirone, WAY 100635, SB 224289, fluoxetine and para-chlorophenylalanine (pCPA) in two behavioral models.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Brain; Buspirone; Disease Models, Animal; D | 2013 |
[Expression of cation-chloride cotransporters KCC2 and NKCC1 in brainstem of para- chlorophenylalanine-induced acute insomnia rats].
Topics: Animals; Brain Stem; Disease Models, Animal; Fenclonine; K Cl- Cotransporters; Male; Rats; Rats, Spr | 2013 |
4-Chloro-DL-phenylalanine protects against monocrotaline‑induced pulmonary vascular remodeling and lung inflammation.
Topics: Animals; Disease Models, Animal; Down-Regulation; Familial Primary Pulmonary Hypertension; Fenclonin | 2014 |
[Effects of extracts from ziziphi spinosae semen and schisandrae chinensis fructus on amino acid neurotransmitter in rats with insomnia induced by PCPA].
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Female; Fenclonine; Fruit; gamma-Aminobutyri | 2013 |
Integrated pharmacokinetics of five protoberberine-type alkaloids in normal and insomnic rats after single and multiple oral administration of Jiao-Tai-Wan.
Topics: Administration, Oral; Animals; Berberine Alkaloids; Disease Models, Animal; Dose-Response Relationsh | 2014 |
Plurality of anxiety and depression alteration mechanism by oleanolic acid.
Topics: alpha-Methyltyrosine; Animals; Anti-Anxiety Agents; Antidepressive Agents; Brain; Brain-Derived Neur | 2014 |
VEGF-induced antidepressant effects involve modulation of norepinephrine and serotonin systems.
Topics: alpha-Methyltyrosine; Animals; Brain; Depression; Disease Models, Animal; Enzyme Inhibitors; Fenclon | 2014 |
Role of Serotonin in MODS: Deficiency of Serotonin Protects Against Zymosan-Induced Multiple Organ Failure in Mice.
Topics: 5-Hydroxytryptophan; Animals; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Fenclonine; Male | 2015 |
Serum serotonin reduced the expression of hepatic transporter Mrp2 and P-gp via regulating nuclear receptor CAR in PI-IBS rats.
Topics: 5-Hydroxytryptophan; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding C | 2015 |
Serotonin Depletion Does not Modify the Short-Term Brain Hypometabolism and Hippocampal Neurodegeneration Induced by the Lithium-Pilocarpine Model of Status Epilepticus in Rats.
Topics: Animals; Disease Models, Animal; Fenclonine; Gliosis; Hippocampus; Lithium; Magnetic Resonance Imagi | 2016 |
Inhalation of Cedrus atlantica essential oil alleviates pain behavior through activation of descending pain modulation pathways in a mouse model of postoperative pain.
Topics: Administration, Inhalation; Adrenergic alpha-2 Receptor Antagonists; alpha-Methyltyrosine; Analgesic | 2015 |
cis-3-Hexenol and trans-2-hexenal mixture prevents development of PTSD-like phenotype in rats.
Topics: Aldehydes; Animals; Conditioning, Psychological; Disease Models, Animal; Drug Evaluation, Preclinica | 2016 |
Tipepidine, a non-narcotic antitussive, exerts an antidepressant-like effect in the forced swimming test in adrenocorticotropic hormone-treated rats.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Benzazepines; Depression; Disease Model | 2016 |
Effects of gonadectomy and serotonin depletion on inter-individual differences in anxiety-like behaviour in male Wistar rats.
Topics: Analysis of Variance; Animals; Anxiety Disorders; Castration; Disease Models, Animal; Fenclonine; Ge | 2016 |
Maternal Inflammation Disrupts Fetal Neurodevelopment via Increased Placental Output of Serotonin to the Fetal Brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Cytokines; Disease Models, Animal; Female; Fenclonine; Fetal De | 2016 |
Panic-modulating effects of alprazolam, moclobemide and sumatriptan in the rat elevated T-maze.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Brain; Disease Models, Animal; Escape Reaction; Explorator | 2016 |
Serotonergic and dopaminergic systems are implicated in antidepressant-like effects of chotosan, a Kampo formula, in mice.
Topics: Animals; Antidepressive Agents; Disease Models, Animal; Dopamine Agents; Drugs, Chinese Herbal; Fenc | 2017 |
Serotonin depletion induces pessimistic-like behavior in a cognitive bias paradigm in pigs.
Topics: Affect; Analysis of Variance; Animals; Brain; Chromatography, High Pressure Liquid; Cognition; Disea | 2017 |
Anticataleptic 8-OH-DPAT preferentially counteracts with haloperidol-induced Fos expression in the dorsolateral striatum and the core region of the nucleus accumbens.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Catalepsy; Corpus Striatum; Disea | 2008 |
An immunohistochemical study of the antinociceptive effect of calcitonin in ovariectomized rats.
Topics: Analgesics; Animals; Biomarkers; Calcitonin; Central Nervous System; Disease Models, Animal; Female; | 2008 |
Neural network detects the effects of p-CPA pre-treatment on brain electrophysiology in a rat model of focal brain injury.
Topics: Algorithms; Animals; Brain; Brain Edema; Brain Injuries; Cerebral Cortex; Disease Models, Animal; El | 2009 |
The brain 5-HT4 receptor binding is down-regulated in the Flinders Sensitive Line depression model and in response to paroxetine administration.
Topics: Animals; Antidepressive Agents, Second-Generation; Autoradiography; Brain; Citalopram; Depression; D | 2009 |
Antidepressant-like effect of the methanolic extract from Bupleurum falcatum in the tail suspension test.
Topics: alpha-Methyltyrosine; Analysis of Variance; Animals; Antidepressive Agents; Bupleurum; Depression; D | 2010 |
A model of symptomatic infantile spasms syndrome.
Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Antibiotics, Antineoplastic; Anticonvulsants | 2010 |
Involvement of monoaminergic system in the antidepressant-like effect of the flavonoid naringenin in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Biogenic Monoamines; Depress | 2010 |
Antidepressant-like effect of carvacrol (5-Isopropyl-2-methylphenol) in mice: involvement of dopaminergic system.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Antidepre | 2011 |
Evaluation of object-based attention in mice.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Attention; Attention Deficit Disorder with Hype | 2011 |
Involvement of GABAergic non-benzodiazepine sites in the anxiolytic-like and sedative effects of the flavonoid baicalein in mice.
Topics: Animals; Anti-Anxiety Agents; Dehydroepiandrosterone Sulfate; Disease Models, Animal; Dose-Response | 2011 |
The role of 5-HT₁A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: a possible antidepressant mechanism.
Topics: Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Depression; Disea | 2012 |
Taltirelin, a thyrotropin-releasing hormone analog, alleviates mechanical allodynia through activation of descending monoaminergic neurons in persistent inflammatory pain.
Topics: Adrenergic Agents; Animals; Biogenic Monoamines; Disease Models, Animal; Dose-Response Relationship, | 2011 |
A possible participation of transient receptor potential vanilloid type 1 channels in the antidepressant effect of fluoxetine.
Topics: Animals; Antidepressive Agents, Second-Generation; Capsaicin; Depression; Disease Models, Animal; Do | 2012 |
Ankle joint mobilization affects postoperative pain through peripheral and central adenosine A1 receptors.
Topics: Adenosine; Analysis of Variance; Animals; Ankle Joint; Caffeine; Clonidine; Disease Models, Animal; | 2013 |
Evidence for a monoamine mediated, opioid-independent, antihyperalgesic effect of venlafaxine, a non-tricyclic antidepressant, in a neurogenic pain model in rats.
Topics: alpha-Methyltyrosine; Analgesics; Animals; Antidepressive Agents; Cyclohexanols; Disease Models, Ani | 2003 |
Evidence for serotonin receptor subtypes involvement in agmatine antidepressant like-effect in the mouse forced swimming test.
Topics: Agmatine; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Depression; Diseas | 2004 |
Role of serotonin (5-HT) in the antidepressant-like properties of neuropeptide Y (NPY) in the mouse forced swim test.
Topics: Animals; Antidepressive Agents; Disease Models, Animal; Fenclonine; Fluoxetine; Male; Mice; Motor Ac | 2005 |
Effects of central and peripheral depletion of serotonergic system on carrageenan-induced paw oedema.
Topics: Animals; Carrageenan; Disease Models, Animal; Drug Administration Schedule; Edema; Fenclonine; Hindl | 2005 |
Anxiolytic effect of serotonin depletion in the novelty-induced hypophagia test.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; | 2007 |
LHRH antagonist attenuates the effect of fluoxetine on marble-burying behavior in mice.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, C | 2007 |
Monoaminergic agents modulate antidepressant-like effect caused by diphenyl diselenide in rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Benzen | 2007 |
Effect of tandospirone on sleep latency in rats placed on a grid suspended over water.
Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Anxiety Agents; Disease Models, Animal; Do | 2007 |
Antidepressive-like effects of electroacupuncture in rats.
Topics: Analysis of Variance; Animals; Depression; Disease Models, Animal; Electroacupuncture; Fenclonine; H | 2008 |
Antidepressant-like effect of agmatine is not mediated by serotonin.
Topics: Agmatine; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Depression; Diseas | 2008 |
Role for serotonin in the antidepressant-like effect of a flavonoid extract of Xiaobuxin-Tang.
Topics: Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Depression; Disease Models, Animal; D | 2008 |
Serotonergic mediation of the antidepressant-like effect of the green leaves odor in mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain Chemistry; Citalopram; Depression; Disease M | 2008 |
Evaluation of the antibradykinetic actions of 5-HT1A agonists using the mouse pole test.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Disease Mod | 2008 |
Effect of hyperphenylalaninemia on Na+ + K+-ATPase in rat brain.
Topics: Adenosine Triphosphatases; Animals; Brain; Ca(2+) Mg(2+)-ATPase; Disease Models, Animal; Enzyme Acti | 1981 |
Analysis of learning in retarded monkeys.
Topics: Animals; Attention; Concept Formation; Discrimination, Psychological; Disease Models, Animal; Female | 1984 |
Effect of hyperphenylalaninemia induced during suckling on brain DNA metabolism in rat pups.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain; Cell Division; Disease Models, Animal; DNA; DN | 1984 |
Constant estrus: role of rostral hypothalamic monoamines in development of reproductive dysfunction in aging rats.
Topics: Aging; Animals; Catecholamines; Diestrus; Disease Models, Animal; Ditiocarb; Estrus; Female; Fenclon | 1980 |
Effect of hyperphenylalaninemia on polyphosphoinositides content of rat brain.
Topics: Animals; Brain; Disease Models, Animal; Fenclonine; Humans; Kinetics; Phenylalanine; Phenylketonuria | 1982 |
Characterization of experimental phenylketonuria. Augmentation of hyperphenylalaninemia with alpha-methylphenylalanine and p-chlorophenylalanine.
Topics: Age Factors; Amino Acids; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Disease Models, A | 1980 |
Phenylketonuria: clinical and experimental considerations revealed by the use of animal models.
Topics: Animals; Brain; Cerebellum; Disease Models, Animal; Fenclonine; Humans; Male; Neurons; Phenylalanine | 1980 |
Induction of an experimental phenylketonuria-like condition in infant rats during the first 2 weeks after birth.
Topics: Animals; Animals, Newborn; Diet; Disease Models, Animal; Female; Fenclonine; Humans; Male; Methotrex | 1981 |
Disturbances of amino acid transport in rats with experimental hyperphenylalaninaemia.
Topics: Amino Acids; Animals; Cerebral Cortex; Disease Models, Animal; Fenclonine; Glycine; Humans; Leucine; | 1981 |
Development of a refractory stage in a dog model for phenylketonuria.
Topics: Animals; Diet; Disease Models, Animal; Dogs; Fenclonine; Humans; Liver; Phenylalanine Hydroxylase; P | 1981 |
Modification of the drug talking behavior in rats by interference in the metabolism of 5-hydroxytryptamine and catecholamines.
Topics: Animals; Choice Behavior; Disease Models, Animal; Dopamine; Drinking Behavior; Female; Fenclonine; H | 1981 |
Serotonin depletion in the adult rat causes loss of the dendritic marker MAP-2. A new animal model of schizophrenia?
Topics: Animals; Biomarkers; Dendrites; Disease Models, Animal; Female; Fenclonine; Hippocampus; Immunohisto | 1995 |
Effects of serotonergic agents on food-restriction-induced hyperactivity.
Topics: Animals; Antidepressive Agents, Tricyclic; Body Weight; Disease Models, Animal; Eating; Female; Fenc | 1996 |
Analgesic mechanism of calcitonin.
Topics: Analgesics; Animals; Calcitonin; Disease Models, Animal; Female; Fenclonine; Hyperalgesia; Models, B | 2000 |
The antidepressant activity of inositol in the forced swim test involves 5-HT(2) receptors.
Topics: Animals; Antidepressive Agents; Benzylamines; Depression; Disease Models, Animal; Drug Interactions; | 2001 |
Inhibition of phenylalanine hydroxylase activity by alpha-methyl tyrosine, a potent inhibitor of tyrosine hydroxylase.
Topics: Animals; Disease Models, Animal; Fenclonine; Humans; Kidney; Liver; Methyltyrosines; Mice; Phenylala | 1975 |
Effect of lithium and other drugs on the amphetamine chlordiazeposice hyperactivity in mice.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Bipolar Disorder; Brain Chemistry; Chlordiazepoxide; Dise | 1975 |
Ultrastructural changes in rat optic nerve associated with hyperphenylalaninemia induced by para-chlorophenylalanine and phenylalanine.
Topics: Animals; Astrocytes; Axons; Cytoplasm; Disease Models, Animal; Endoplasmic Reticulum; Fenclonine; Go | 1975 |
In vivo inhibition of rat liver phenylalanine hydroxylase by p-chlorophenylalanine and Esculin. Experimental model of phenylketonuria.
Topics: Animals; Disease Models, Animal; Esculin; Female; Fenclonine; Flavonoids; Humans; Liver; Phenylalani | 1975 |
Urinary metabolites of phenylalanine in the preweanling rat treated with p-chlorophenylalanine and phenylalanine.
Topics: Animals; Chromatography; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fenclonin | 1975 |
Brain uptake and protein incorporation of amino acids studied in rats subjected to prolonged hyperphenylalaninaemia.
Topics: Amino Acids; Animals; Brain; Disease Models, Animal; Female; Fenclonine; Glycine; Humans; Leucine; L | 1975 |
Model phenylketonuria (PKU) in the albino rat: behaviroal, biochemical, and neuroanatomical effects.
Topics: Animals; Axons; Body Weight; Disease Models, Animal; Emotions; Fenclonine; Humans; Learning; Liver; | 1975 |
The regulation of phenylalanine hydroxylase in rat tissues in vivo. The maintenance of high plasma phenylalanine concentrations in suckling rats: a model for phenylketonuria.
Topics: Animals; Brain; Disease Models, Animal; Fenclonine; Humans; Kidney; Liver; Male; Phenylalanine; Phen | 1976 |
A study of psychomotor epilepsy with "kindled" cat preparations.
Topics: Amygdala; Animals; Cats; Disease Models, Animal; Dopamine; Electric Stimulation; Electroencephalogra | 1976 |
Attempt to influence pharmacologically spinal cord tissue changes after an experimental injury.
Topics: Animals; Aprotinin; Disease Models, Animal; Female; Fenclonine; Male; Methyltyrosines; Rabbits; Spin | 1975 |
Study of blood aminoacids in experimental hyperphenylalaninemia.
Topics: Amino Acids; Animals; Disease Models, Animal; Fenclonine; Humans; Male; Phenylalanine; Phenylketonur | 1977 |
Serotonin as a factor in depression of collateral blood flow following experimental arterial thrombosis.
Topics: Animals; Aorta, Abdominal; Aortic Diseases; Blood Cell Count; Blood Platelets; Cats; Cinanserin; Col | 1977 |
A new experimental model of hyperphenylalaninemia in rat. Effect of p-chlorophenylalanine and cotrimoxazole.
Topics: Animals; Disease Models, Animal; Drug Combinations; Fenclonine; Humans; Kidney; Liver; Male; Phenyla | 1977 |
[Action of parachlorophenylalanine on arterial hypertension induced by the use of an unavoidable plantar electric shock].
Topics: Animals; Behavior, Animal; Disease Models, Animal; Electroshock; Fenclonine; Hypertension; Rats; Ser | 1977 |
Animal model of depression. III. Mechanism of action of tetrabenazine.
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Depression; Disease Models, Animal; Dopamine; | 1978 |
Myelin deficiency in experimental phenylketonuria: contribution of the aromatic acid metabolites of phenylalanine.
Topics: Animals; Brain; Disease Models, Animal; Female; Fenclonine; Humans; Male; Membrane Lipids; Myelin Pr | 1978 |
Experimental phenylketonuria: metabolic studies in rat liver.
Topics: Animals; Disease Models, Animal; Fasting; Female; Fenclonine; Fructosephosphates; Gluconeogenesis; G | 1977 |
Effects of idebenone on metabolism of monoamines and cyclic AMP formation in rats.
Topics: Animals; Benzoquinones; Biogenic Monoamines; Brain; Brain Ischemia; Cyclic AMP; Disease Models, Anim | 1989 |
Effects of phenylalanine loading on protein synthesis in the fetal heart and brain of rat: an experimental approach to maternal phenylketonuria.
Topics: Animals; Brain; Carbon Radioisotopes; Disease Models, Animal; Female; Fenclonine; Fetal Heart; Fetus | 1986 |
Studies on experimentally induced hyperphenylalaninemia.
Topics: Animals; Disease Models, Animal; Drug Combinations; Female; Fenclonine; Phenylalanine; Phenylalanine | 1988 |
Influence of changes in brain monoamine metabolism on behaviour of herpes simplex-infected mice.
Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Brain; Clonidine; Dihydroxyphenylalanine; Diseas | 1974 |
The influence of cinanserin and selected pharmacologic agents on experimental allergic encephalomyelitis (EAE).
Topics: 5-Hydroxytryptophan; Amphetamine; Anilides; Animals; Azathioprine; Body Weight; Chlorpheniramine; Ci | 1971 |
Enduring behavioral changes in rats with experimental phenylketonuria.
Topics: Aggression; Animals; Appetitive Behavior; Avoidance Learning; Behavior, Animal; Brain; Defecation; D | 1972 |
On the mechanism of fever caused by the mucopeptide of group A streptococcus.
Topics: Animals; Bacterial Proteins; Brain; Disease Models, Animal; Fenclonine; Fever; Injections, Intraveno | 1972 |
Cataractogenesis in infant rats with model phenylketonuria.
Topics: Age Factors; Animals; Animals, Newborn; Cataract; Disease Models, Animal; Female; Fenclonine; Humans | 1972 |
Behavioral effects of experimental maternal hyperphenylalaninemia.
Topics: Animals; Animals, Newborn; Avoidance Learning; Behavior, Animal; Disease Models, Animal; Exploratory | 1973 |
Experimental maternal hyperphenylalaninemia: biochemical effects and offspring development.
Topics: Aggression; Animals; Animals, Newborn; Body Weight; Brain; Brain Chemistry; Disease Models, Animal; | 1974 |
Control of liver and brain aromatic amino-acid metabolism by phenylalanine hydroxylase.
Topics: Animals; Brain; Brain Chemistry; Chemical Phenomena; Chemistry; Disease Models, Animal; Electrophore | 1973 |