Page last updated: 2024-11-02

fenclonine and Dementia Praecox

fenclonine has been researched along with Dementia Praecox in 5 studies

Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DeLisi, LE1
Freed, WJ1
Gillin, JC1
Kleinman, JE1
Bigelow, LB1
Wyatt, RJ1
Whitaker-Azmitia, PM1
Borella, A1
Raio, N1
Casacchia, M1
Casati, C1
Fazio, C1
Laplante, M1
St-Laurent, J1
Koella, WP1

Reviews

2 reviews available for fenclonine and Dementia Praecox

ArticleYear
[Research into the biochemical bases of schizophrenic syndromes: a review].
    L'union medicale du Canada, 1973, Volume: 102, Issue:11

    Topics: Alpha-Globulins; Amphetamine; Ceruloplasmin; Energy Metabolism; Fenclonine; gamma-Globulins; Halluci

1973
What is the functional role of central nervous serotonin?
    Neurosciences research, 1969, Volume: 2, Issue:0

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature Regulation; Brain; Cats; Central Nervous System; Circ

1969

Trials

1 trial available for fenclonine and Dementia Praecox

ArticleYear
Letter: p-Chlorophenylalanine in schizophrenia.
    Biological psychiatry, 1975, Volume: 10, Issue:1

    Topics: Administration, Oral; Clinical Trials as Topic; Drug Evaluation; Fenclonine; Humans; Remission, Spon

1975

Other Studies

2 other studies available for fenclonine and Dementia Praecox

ArticleYear
P-chlorophenylalanine trials in schizophrenic patients.
    Biological psychiatry, 1982, Volume: 17, Issue:4

    Topics: Adult; Female; Fenclonine; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophre

1982
Serotonin depletion in the adult rat causes loss of the dendritic marker MAP-2. A new animal model of schizophrenia?
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1995, Volume: 12, Issue:3

    Topics: Animals; Biomarkers; Dendrites; Disease Models, Animal; Female; Fenclonine; Hippocampus; Immunohisto

1995