fenclonine has been researched along with Dementia Praecox in 5 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DeLisi, LE | 1 |
| Freed, WJ | 1 |
| Gillin, JC | 1 |
| Kleinman, JE | 1 |
| Bigelow, LB | 1 |
| Wyatt, RJ | 1 |
| Whitaker-Azmitia, PM | 1 |
| Borella, A | 1 |
| Raio, N | 1 |
| Casacchia, M | 1 |
| Casati, C | 1 |
| Fazio, C | 1 |
| Laplante, M | 1 |
| St-Laurent, J | 1 |
| Koella, WP | 1 |
2 reviews available for fenclonine and Dementia Praecox
| Article | Year |
|---|---|
[Research into the biochemical bases of schizophrenic syndromes: a review].
Topics: Alpha-Globulins; Amphetamine; Ceruloplasmin; Energy Metabolism; Fenclonine; gamma-Globulins; Halluci | 1973 |
What is the functional role of central nervous serotonin?
Topics: 5-Hydroxytryptophan; Animals; Body Temperature Regulation; Brain; Cats; Central Nervous System; Circ | 1969 |
1 trial available for fenclonine and Dementia Praecox
| Article | Year |
|---|---|
Letter: p-Chlorophenylalanine in schizophrenia.
Topics: Administration, Oral; Clinical Trials as Topic; Drug Evaluation; Fenclonine; Humans; Remission, Spon | 1975 |
2 other studies available for fenclonine and Dementia Praecox
| Article | Year |
|---|---|
P-chlorophenylalanine trials in schizophrenic patients.
Topics: Adult; Female; Fenclonine; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophre | 1982 |
Serotonin depletion in the adult rat causes loss of the dendritic marker MAP-2. A new animal model of schizophrenia?
Topics: Animals; Biomarkers; Dendrites; Disease Models, Animal; Female; Fenclonine; Hippocampus; Immunohisto | 1995 |