Page last updated: 2024-11-02

fenclonine and Decerebrate Posturing

fenclonine has been researched along with Decerebrate Posturing in 18 studies

Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.

Research Excerpts

ExcerptRelevanceReference
" In this study, we investigated the antinociceptive action of neurotropin in relation to the serotonergic system, a pain inhibitory system, and substance P, a pain transmitter; we also attempted to determine whether it acts at the spinal or supraspinal level in mice."3.67Analgesic mechanism of neurotropin: relation to the serotonergic system and influence of spinal cord transection. ( Hata, T; Itoh, E, 1989)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199014 (77.78)18.7374
1990's3 (16.67)18.2507
2000's1 (5.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Honda, M1
Nishida, T1
Ono, H2
Kobayashi, H1
Hasegawa, Y1
Bell, JA1
Martin, WR1
Sloan, JW1
Buchwald, WF1
Wang, RY1
Aghajanian, GK1
Iwata, N1
Kobayashi, K1
Hara, T1
Matsumura, M1
Mikuni, N1
Deguch, T1
Neal, H2
Bradley, PB1
Bond, A1
Thut, PD1
Myslinski, NR2
Anderson, MF1
Mokler, DJ1
Winterson, BJ1
Itoh, E1
Hata, T1
Tangri, KK2
Gupta, GP1
Vrat, S2
Saxena, AK1
Saksena, AK1
Puizillout, JJ1
Ternaux, JP1
Foutz, AS1
Fernandez, G1
Sinclair, JG2
Sastry, BS2
Flórez, J2
Delgado, G2
Armijo, JA2

Other Studies

18 other studies available for fenclonine and Decerebrate Posturing

ArticleYear
Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT(2) receptors.
    European journal of pharmacology, 2003, Jan-01, Volume: 458, Issue:1-2

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cyproheptadine; Decerebrate State; Dose-Re

2003
Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems.
    European journal of pharmacology, 1996, Sep-05, Volume: 311, Issue:1

    Topics: Adrenergic alpha-2 Receptor Antagonists; Amitriptyline; Animals; Decerebrate State; Fenclonine; Male

1996
The effect of L-tryptophan on spinal cord C-fiber reflexes.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 196, Issue:2

    Topics: 5-Hydroxytryptophan; Action Potentials; Animals; Carboxy-Lyases; Cats; Cyproheptadine; Decerebrate S

1976
Inhibiton of neurons in the amygdala by dorsal raphe stimulation: mediation through a direct serotonergic pathway.
    Brain research, 1977, Jan-14, Volume: 120, Issue:1

    Topics: 5-Hydroxytryptophan; Action Potentials; Amygdala; Animals; Brain Stem; Cyproheptadine; Decerebrate S

1977
[Effects of a new psychotropic agent, CS-430, on the central nervous system of experimental animals (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1978, Volume: 74, Issue:7

    Topics: Amygdala; Animals; Arousal; Benzodiazepinones; Cats; Central Nervous System; Decerebrate State; Elec

1978
Electrophysiological studies with a new anti-depressant drug: comparison of the effects of viloxazine (ICI 58,834) with three tricyclic anti-depressants in the encéphale isolé.
    Neuropharmacology, 1978, Volume: 17, Issue:10

    Topics: Animals; Antidepressive Agents, Tricyclic; Cats; Decerebrate State; Desipramine; Electroencephalogra

1978
Modification of PGO activity by specific uptake inhibitors fluoxetine, nisoxetine and LR5182.
    Neuropharmacology, 1979, Volume: 18, Issue:10

    Topics: 2H-Benzo(a)quinolizin-2-ol, 2-Ethyl-1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-; Animals; Bri

1979
The role of dopamine and serotonin in the prolongation of post-decapitation convulsions in mice.
    Life sciences, 1976, Nov-15, Volume: 19, Issue:10

    Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Decerebrate State; Ditiocarb; Dopamine; Fenclonine

1976
Inhibition of chronic hindlimb flexion in rat: evidence for mediation by 5-hydroxytryptamine.
    Brain research, 1991, Feb-15, Volume: 541, Issue:2

    Topics: Animals; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Fenclonine; Hind

1991
The involvement of bulbospinal serotonergic neurons in the effect of 5-hydroxytryptophan on alpha and gamma motoneurons.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: 5-Hydroxytryptophan; Animals; Cats; Cinanserin; Decerebrate State; Drug Synergism; Female; Fenclonin

1991
Analgesic mechanism of neurotropin: relation to the serotonergic system and influence of spinal cord transection.
    Japanese journal of pharmacology, 1989, Volume: 51, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Cisterna Magna; Cyproheptadine; Decerebrate State; Fenclonine

1989
Role of histamine receptor in mesencephalic nucleus dorsalis raphe in cardiovascular regulation.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 339, Issue:5

    Topics: Animals; Cardiovascular Physiological Phenomena; Cats; Cimetidine; Decerebrate State; Female; Fenclo

1989
Presence of opioid receptors in mesencephalic nucleus dorsalis raphe concerned in cardiovascular regulation in cats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Decerebrate State; Female; Fenclonine;

1987
[Sleep stages in "encéphale isolé" preparations: I. Triggering of ponto-geniculo-occipital spikes and slow-wave sleep. The role of the nuclei of the raphe].
    Electroencephalography and clinical neurophysiology, 1974, Volume: 37, Issue:6

    Topics: Animals; Blood Pressure; Cats; Decerebrate State; Electric Stimulation; Electrocardiography; Electro

1974
The blockade of bulbospinal inhibition by imipramine, desipramine and pargyline.
    Neuropharmacology, 1974, Volume: 13, Issue:7

    Topics: Animals; Cats; Caudate Nucleus; Decerebrate State; Desipramine; Electric Stimulation; Electrodes, Im

1974
Adrenergic and serotonergic mechanisms in morphine-induced respiratory depression.
    Psychopharmacologia, 1972, Volume: 24, Issue:2

    Topics: Animals; Brain; Cats; Decerebrate State; Drug Synergism; Fenclonine; Morphine; Norepinephrine; Pargy

1972
Brain amines and development of acute tolerance to and dependence on morphine in the respiratory center of decerebrate cats.
    Neuropharmacology, 1973, Volume: 12, Issue:4

    Topics: Amines; Animals; Blood Pressure; Carbon Dioxide; Cats; Decerebrate State; Drug Tolerance; Fenclonine

1973
Supraspinal monoaminergic involvement in the blockade of recurrent inhibition of the monosynaptic reflex.
    Neuropharmacology, 1974, Volume: 13, Issue:8

    Topics: Animals; Biogenic Amines; Blood Pressure; Cats; Conditioning, Operant; Decerebrate State; Fenclonine

1974