fenclonine has been researched along with Chronic Illness in 3 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have studied the role of 5-hydroxytryptamine (5-HT) in monocrotaline pulmonary hypertension and chronic hypoxic pulmonary hypertension in rats using p-chlorophenylalanine (PCPA) which inhibits 5-HT synthesis." | 7.67 | Pulmonary hypertension induced in rats by monocrotaline and chronic hypoxia is reduced by p-chlorophenylalanine. ( Kay, JM; Keane, PM; Suyama, KL, 1985) |
| "We have studied the role of 5-hydroxytryptamine (5-HT) in monocrotaline pulmonary hypertension and chronic hypoxic pulmonary hypertension in rats using p-chlorophenylalanine (PCPA) which inhibits 5-HT synthesis." | 3.67 | Pulmonary hypertension induced in rats by monocrotaline and chronic hypoxia is reduced by p-chlorophenylalanine. ( Kay, JM; Keane, PM; Suyama, KL, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lapiz-Bluhm, MD | 1 |
| Soto-Piña, AE | 1 |
| Hensler, JG | 1 |
| Morilak, DA | 1 |
| Izikki, M | 1 |
| Hanoun, N | 1 |
| Marcos, E | 1 |
| Savale, L | 1 |
| Barlier-Mur, AM | 1 |
| Saurini, F | 1 |
| Eddahibi, S | 1 |
| Hamon, M | 1 |
| Adnot, S | 1 |
| Kay, JM | 1 |
| Keane, PM | 1 |
| Suyama, KL | 1 |
3 other studies available for fenclonine and Chronic Illness
| Article | Year |
|---|---|
Chronic intermittent cold stress and serotonin depletion induce deficits of reversal learning in an attentional set-shifting test in rats.
Topics: Animals; Attention; Chronic Disease; Citalopram; Cold Temperature; Discrimination Learning; Fencloni | 2009 |
Tryptophan hydroxylase 1 knockout and tryptophan hydroxylase 2 polymorphism: effects on hypoxic pulmonary hypertension in mice.
Topics: Animals; Chronic Disease; Enzyme Inhibitors; Fenclonine; Hypertension, Pulmonary; Hypoxia; Intestina | 2007 |
Pulmonary hypertension induced in rats by monocrotaline and chronic hypoxia is reduced by p-chlorophenylalanine.
Topics: Animals; Chronic Disease; Female; Fenclonine; Hypertension, Pulmonary; Hypoxia; Monocrotaline; Pyrro | 1985 |