Page last updated: 2024-11-02

fenclonine and Chemical Dependence

fenclonine has been researched along with Chemical Dependence in 8 studies

Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nabeshima, T1
Ho, IK1
Tagashira, E1
Hiramori, T1
Urano, T1
Yanaura, S1
Fuchs, V1
Coper, H1
Nickel, B1
Herz, A1
Jakovlev, V1
Tibes, U1
Pozuelo, J1
Kerr, FW1
Collier, HO1
Post, RM1
Goodwin, FK1
Chernik, DA1
Ramsey, TA1
Mendels, J1

Reviews

1 review available for fenclonine and Chemical Dependence

ArticleYear
Drug dependence: a pharmacological analysis.
    The British journal of addiction to alcohol and other drugs, 1972, Volume: 67, Issue:4

    Topics: Acetylcholine; Animals; Atropine; Brain Chemistry; Catecholamines; Cerebral Cortex; Chemoreceptor Ce

1972

Trials

1 trial available for fenclonine and Chemical Dependence

ArticleYear
Estimation of brain amine metabolism in affective illness: cerebrospinal fluid studies utilizing probenecid.
    Psychotherapy and psychosomatics, 1974, Volume: 23, Issue:1-6

    Topics: Bipolar Disorder; Brain; Depression; Dihydroxyphenylalanine; Fenclonine; Homovanillic Acid; Humans;

1974

Other Studies

6 other studies available for fenclonine and Chemical Dependence

ArticleYear
Acute and chronic effects of pentobarbital on 5-hydroxytryptamine in mouse brain.
    Progress in neuro-psychopharmacology, 1981, Volume: 5, Issue:4

    Topics: Animals; Brain; Dopamine; Drug Tolerance; Fenclonine; Humans; Hydroxyindoleacetic Acid; Kinetics; Ma

1981
Formation of physical dependence on barbiturates and cerebral monoamines.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:2

    Topics: alpha-Methyltyrosine; Animals; Barbital; Barbiturates; Biogenic Amines; Body Weight; Brain; Catechol

1983
Modification of the drug talking behavior in rats by interference in the metabolism of 5-hydroxytryptamine and catecholamines.
    Drug and alcohol dependence, 1981, Volume: 8, Issue:3

    Topics: Animals; Choice Behavior; Disease Models, Animal; Dopamine; Drinking Behavior; Female; Fenclonine; H

1981
[Mechanism of action of the analgesic flupirtine].
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:9

    Topics: Aminopyridines; Analgesics; Animals; Brain; Cyproheptadine; Fenclonine; Injections, Intraventricular

1985
Suppression of craving and other signs of dependence in morphine-addicted monkeys by administration of alpha-methyl-para-tyrosine.
    Mayo Clinic proceedings, 1972, Volume: 47, Issue:9

    Topics: Animals; Female; Fenclonine; Haloperidol; Haplorhini; Humans; Hypothalamus; Injections, Intravenous;

1972
The effect of parachlorophenylalanine on the sleep of a methadone addict.
    The British journal of psychiatry : the journal of mental science, 1973, Volume: 122, Issue:567

    Topics: Action Potentials; Adult; Electroencephalography; Electromyography; Electrooculography; Fenclonine;

1973