fenclonine has been researched along with Brain Injuries in 8 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sinha, RK | 1 |
| Aggarwal, Y | 1 |
| Kuo, JR | 1 |
| Cheng, YH | 1 |
| Chen, YS | 1 |
| Chio, CC | 1 |
| Gean, PW | 1 |
| Sharma, HS | 1 |
| Winkler, T | 1 |
| Stålberg, E | 1 |
| Mohanty, S | 1 |
| Westman, J | 1 |
| Archer, DP | 1 |
| Priddy, RE | 1 |
| Tang, TK | 1 |
| Sabourin, MA | 1 |
| Samanani, N | 1 |
| Pappius, HM | 3 |
| Dadoun, R | 1 |
| McHugh, M | 1 |
| Marsden, CA | 1 |
| Guldberg, HC | 1 |
8 other studies available for fenclonine and Brain Injuries
| Article | Year |
|---|---|
Neural network detects the effects of p-CPA pre-treatment on brain electrophysiology in a rat model of focal brain injury.
Topics: Algorithms; Animals; Brain; Brain Edema; Brain Injuries; Cerebral Cortex; Disease Models, Animal; El | 2009 |
Involvement of extracellular signal regulated kinases in traumatic brain injury-induced depression in rodents.
Topics: Animals; Anxiety; Blotting, Western; Brain Injuries; Coloring Agents; Depression; Extracellular Sign | 2013 |
p-Chlorophenylalanine, an inhibitor of serotonin synthesis reduces blood-brain barrier permeability, cerebral blood flow, edema formation and cell injury following trauma to the rat brain.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Capillary Permeability; Cell Survi | 2000 |
The influence of cryogenic brain injury on the pharmacodynamics of pentobarbital. Evidence for a serotonergic mechanism.
Topics: Animals; Brain Injuries; Fenclonine; Freezing; Infusions, Intravenous; Male; Pentobarbital; Rats; Ra | 1991 |
The effect of p-chlorophenylalanine on cerebral metabolism and biogenic amine content of traumatized brain.
Topics: Animals; Biogenic Amines; Brain; Brain Injuries; Cerebral Cortex; Fenclonine; Glucose; Hydroxyindole | 1988 |
Involvement of indoleamines in functional disturbances after brain injury.
Topics: Animals; Biogenic Amines; Brain; Brain Injuries; Cerebral Cortex; Deoxyglucose; Fenclonine; Hydroxyi | 1989 |
Significance of biogenic amines in functional disturbances resulting from brain injury.
Topics: Animals; Biogenic Amines; Brain Injuries; Cerebral Cortex; Fenclonine; Freezing; Glucose; Male; Praz | 1988 |
The role of monoamines in rotation induced or potentiated by amphetamine after nigral, raphe and mesencephalic reticular lesions in the rat brain.
Topics: Amines; Amphetamine; Animals; Behavior, Animal; Brain; Brain Injuries; Catalepsy; Cerebral Cortex; C | 1973 |