fenclonine has been researched along with Bipolar Disorder in 9 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Silva, EF | 1 |
| Silva, AI | 1 |
| Asth, L | 1 |
| Souza, LS | 1 |
| Zaveri, NT | 1 |
| Guerrini, R | 1 |
| Calo', G | 1 |
| Ruzza, C | 1 |
| Gavioli, EC | 1 |
| Poitou, P | 1 |
| Boulu, R | 1 |
| Bohuon, C | 1 |
| Benkert, O | 1 |
| Shopsin, B | 2 |
| Friedman, E | 1 |
| Gershon, S | 2 |
| Luchins, D | 1 |
| Wilk, S | 1 |
| Murphy, DL | 1 |
| Campbell, IC | 1 |
| Costa, JL | 1 |
| Sjöström, R | 1 |
| Post, RM | 1 |
| Goodwin, FK | 1 |
2 reviews available for fenclonine and Bipolar Disorder
| Article | Year |
|---|---|
Biogenic amines and affective disorders. A critical analysis.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar | 1976 |
The brain serotonergic system in the affective disorders.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Animals; Bipolar Disorder; Brain; Brain Chemistry; Fencloni | 1978 |
3 trials available for fenclonine and Bipolar Disorder
| Article | Year |
|---|---|
Studies on pituitary hormones and releasing hormones in depression and sexual impotence.
Topics: 5-Hydroxytryptophan; Benserazide; Bipolar Disorder; Clinical Trials as Topic; Depression; Erectile D | 1975 |
Biogenic amines and affective disorders. A critical analysis.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar | 1976 |
Estimation of brain amine metabolism in affective illness: cerebrospinal fluid studies utilizing probenecid.
Topics: Bipolar Disorder; Brain; Depression; Dihydroxyphenylalanine; Fenclonine; Homovanillic Acid; Humans; | 1974 |
5 other studies available for fenclonine and Bipolar Disorder
| Article | Year |
|---|---|
Nociceptin/orphanin FQ receptor agonists increase aggressiveness in the mouse resident-intruder test.
Topics: Aggression; Agonistic Behavior; Animals; Anxiety; Bipolar Disorder; Carbamazepine; Cycloheptanes; De | 2019 |
Effect of lithium and other drugs on the amphetamine chlordiazeposice hyperactivity in mice.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Bipolar Disorder; Brain Chemistry; Chlordiazepoxide; Dise | 1975 |
Parachlorophenylalanine reversal of tranylcypromine effects in depressed patients.
Topics: Bipolar Disorder; Drug Therapy, Combination; Fenclonine; Humans; Time Factors; Tranylcypromine | 1976 |
Exploration of affective illness.
Topics: Adult; Bipolar Disorder; Brain; Depression; Dose-Response Relationship, Drug; Drug Therapy, Combinat | 1976 |
Absence of effect of para-chlorophenylalanine on 5-hydroxyindoleacetic acid in cerebrospinal fluid in man.
Topics: Adult; Aged; Bipolar Disorder; Drug Interactions; Female; Fenclonine; Humans; Hydroxyindoleacetic Ac | 1972 |