fenclonine has been researched along with Bile Duct Cancer in 1 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cholangiocarcinoma is a devastating cancer of biliary origin with limited treatment options." | 1.35 | Serotonin metabolism is dysregulated in cholangiocarcinoma, which has implications for tumor growth. ( Alpini, G; Alvaro, D; Benedetti, A; Bernuzzi, F; Coufal, M; DeMorrow, S; Frampton, G; Franchitto, A; Gaudio, E; Invernizzi, P; Kopriva, S; Lee, SP; Marzioni, M; Onori, P; Venter, J, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alpini, G | 1 |
| Invernizzi, P | 1 |
| Gaudio, E | 1 |
| Venter, J | 1 |
| Kopriva, S | 1 |
| Bernuzzi, F | 1 |
| Onori, P | 1 |
| Franchitto, A | 1 |
| Coufal, M | 1 |
| Frampton, G | 1 |
| Alvaro, D | 1 |
| Lee, SP | 1 |
| Marzioni, M | 1 |
| Benedetti, A | 1 |
| DeMorrow, S | 1 |
1 other study available for fenclonine and Bile Duct Cancer
| Article | Year |
|---|---|
Serotonin metabolism is dysregulated in cholangiocarcinoma, which has implications for tumor growth.
Topics: Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cholangiocarcinoma; Chromo | 2008 |