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fenclonine and Anorexia

fenclonine has been researched along with Anorexia in 7 studies

Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.

Anorexia: The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA.

Research Excerpts

ExcerptRelevanceReference
"In vivo 5-HT release and regional hypothalamic 5-HT and tryptophan concentrations were measured in rats with 2,4,6,-trinitrobenzene sulfonic acid (TNBS)-induced colitis, healthy controls, and animals pair-fed to match the food intake of the colitic group."3.70The role of medial hypothalamic serotonin in the suppression of feeding in a rat model of colitis. ( Ballinger, A; Dryden, S; El-Haj, T; Farthing, MJ; Obeid, O; Perrett, D; Turvill, J; Williams, G, 2000)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderberg, RH1
Richard, JE1
Eerola, K1
López-Ferreras, L1
Banke, E1
Hansson, C1
Nissbrandt, H1
Berqquist, F1
Gribble, FM1
Reimann, F1
Wernstedt Asterholm, I1
Lamy, CM1
Skibicka, KP1
Rowland, NE1
Roth, JD1
McMullen, MR1
Patel, A1
Cespedes, AT1
Ballinger, A1
El-Haj, T1
Perrett, D1
Turvill, J1
Obeid, O1
Dryden, S1
Williams, G1
Farthing, MJ1
Sugrue, MF1
Goodlet, I1
McIndewar, I1
Gietzen, DW2
Hammer, VA1
Beverly, JL1
Rogers, QR2
Leung, PM1
Semon, B1
Piechota, T1
Dourish, CT1
Hutson, PH1
Kennett, GA1
Curzon, G1

Reviews

1 review available for fenclonine and Anorexia

ArticleYear
The role of serotonin (5-HT) in feeding responses to amino acids.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Amino Acids; Animals; Anorexia; Appetite; Brain; Diet; Eating; Fenclonine; Male; Models, Biological;

1991

Other Studies

6 other studies available for fenclonine and Anorexia

ArticleYear
Glucagon-Like Peptide 1 and Its Analogs Act in the Dorsal Raphe and Modulate Central Serotonin to Reduce Appetite and Body Weight.
    Diabetes, 2017, Volume: 66, Issue:4

    Topics: Aminopyridines; Animals; Anorexia; Appetite; Body Weight; Dorsal Raphe Nucleus; Exenatide; Feeding B

2017
Dexfenfluramine and norfenfluramine: comparison of mechanism of action in feeding and brain Fos-ir studies.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 278, Issue:2

    Topics: 5,7-Dihydroxytryptamine; Animals; Anorexia; Behavior, Animal; Brain; Dexfenfluramine; Eating; Female

2000
The role of medial hypothalamic serotonin in the suppression of feeding in a rat model of colitis.
    Gastroenterology, 2000, Volume: 118, Issue:3

    Topics: Amino Acids; Animals; Anorexia; Colitis; Drinking; Eating; Fenclonine; Hydroxyindoleacetic Acid; Hyp

2000
Failure of depletion of rat brain 5-hydroxytryptamine to alter fenfluramine-induced anorexia.
    The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:12

    Topics: 5,6-Dihydroxytryptamine; Animals; Anorexia; Appetite; Brain; Depression, Chemical; Dopamine; Fenclon

1975
Serotonin and feeding responses of rats to amino acid imbalance: initial phase.
    The American journal of physiology, 1987, Volume: 253, Issue:5 Pt 2

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amino Acids; Animals; Anorexia; Die

1987
8-OH-DPAT-induced hyperphagia: its neural basis and possible therapeutic relevance.
    Appetite, 1986, Volume: 7 Suppl

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Biogenic Amines; Brain; Feeding Behavior;

1986