fenclonine has been researched along with Alloxan Diabetes in 6 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Therapeutic potential of agomelatine on neuropathic pain was suppressed with α-methyl-para-tyrosine methyl ester (an inhibitor of catecholamine synthesis), phentolamine (a nonselective α-adrenoceptor antagonist), and propranolol (a nonselective β-adrenoceptor antagonist) administrations." | 1.43 | Effect of subacute agomelatine treatment on painful diabetic neuropathy: involvement of catecholaminergic mechanisms. ( Aydın, TH; Can, ÖD; Demir Özkay, Ü; Turan, N, 2016) |
| "In both cases, prior induction of primary hypothyroidism interfered with the expected diabetes-induced reduction in 5-HT turnover." | 1.28 | Streptozotocin-induced decreases in serotonin turnover are prevented by thyroidectomy. ( Bellush, LL; Henley, WN, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aydın, TH | 1 |
| Can, ÖD | 1 |
| Demir Özkay, Ü | 1 |
| Turan, N | 1 |
| Takeshita, N | 1 |
| Ohkubo, Y | 1 |
| Yamaguchi, I | 1 |
| Yang, YF | 1 |
| Lin, MT | 1 |
| Smith, SA | 1 |
| Pogson, CL | 1 |
| Henley, WN | 1 |
| Bellush, LL | 1 |
| Kolta, MG | 1 |
| Soliman, KF | 1 |
| Williams, BB | 1 |
6 other studies available for fenclonine and Alloxan Diabetes
| Article | Year |
|---|---|
Effect of subacute agomelatine treatment on painful diabetic neuropathy: involvement of catecholaminergic mechanisms.
Topics: Acetamides; Animals; Blood Glucose; Catecholamines; Diabetes Mellitus, Experimental; Diabetic Neurop | 2016 |
Tiapride attenuates pain transmission through an indirect activation of central serotonergic mechanism.
Topics: Animals; Central Nervous System; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dopamine An | 1995 |
Brain serotonin depletion attenuates diabetogenic effects of streptozotocin.
Topics: 5,7-Dihydroxytryptamine; Animals; Brain; Diabetes Mellitus, Experimental; Dopamine; Fenclonine; Male | 1995 |
Tryptophan and the control of plasma glucose concentrations in the rat.
Topics: 5-Hydroxytryptophan; Adrenalectomy; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fenclon | 1977 |
Streptozotocin-induced decreases in serotonin turnover are prevented by thyroidectomy.
Topics: Animals; Corticosterone; Diabetes Mellitus, Experimental; Exploratory Behavior; Fenclonine; Hydroxyi | 1992 |
Role of 5-hydroxytryptamine in the regulation of brain neuropeptides in normal and diabetic rat.
Topics: Animals; beta-Endorphin; Brain; Diabetes Mellitus, Experimental; Dopamine; Endorphins; Fenclonine; F | 1986 |