fenclonine has been researched along with Acute Confusional Senile Dementia in 1 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present results suggest that, in Alzheimer's disease, combined degeneration of nucleus basalis cholinergic and brainstem serotonergic cells decreases the therapeutic effect of nicotine, but not that of tetrahydroaminoacridine." | 1.29 | Effects of tetrahydroaminoacridine and nicotine in nucleus basalis and serotonin-lesioned rats. ( Riekkinen, M; Riekkinen, P, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Riekkinen, P | 1 |
| Riekkinen, M | 1 |
1 other study available for fenclonine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Effects of tetrahydroaminoacridine and nicotine in nucleus basalis and serotonin-lesioned rats.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Avoidance Learning; Basal Ganglia; Cerebral Cortex | 1995 |