fenclonine has been researched along with Action Tremor in 16 studies
Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We previously demonstrated that nicotine elicited kinetic tremor by elevating the neural activity of the inferior olive via α7 nicotinic acetylcholine (nACh) receptors." | 7.85 | Serotonergic modulation of nicotine-induced kinetic tremor in mice. ( Iha, HA; Kunisawa, N; Matsubara, N; Nomura, Y; Ohno, Y; Onishi, M; Shimizu, S, 2017) |
| "Specific beta 1- and beta 2-adrenoceptor antagonists, acebutolol and butoxamine respectively were used to investigate the involvement of blockade of these receptors in the inhibition of harmaline-induced tremors." | 7.67 | Involvement of beta 2-adrenoceptor blockade and 5-hydroxytryptamine mechanism in inhibition of harmaline-induced tremors in rats. ( Paul, V, 1986) |
| "Alterations of steady state and metabolism of putative neurotransmitters were studied in the brain of rats with a sustained tremor evoked by nicotine and pilocarpine." | 7.66 | Possible mechanisms of sustained tremor induction by nicotine in pilocarpine treated animals. ( Dohi, T; Tsujimoto, A, 1978) |
| "We previously demonstrated that nicotine elicited kinetic tremor by elevating the neural activity of the inferior olive via α7 nicotinic acetylcholine (nACh) receptors." | 3.85 | Serotonergic modulation of nicotine-induced kinetic tremor in mice. ( Iha, HA; Kunisawa, N; Matsubara, N; Nomura, Y; Ohno, Y; Onishi, M; Shimizu, S, 2017) |
| "Specific beta 1- and beta 2-adrenoceptor antagonists, acebutolol and butoxamine respectively were used to investigate the involvement of blockade of these receptors in the inhibition of harmaline-induced tremors." | 3.67 | Involvement of beta 2-adrenoceptor blockade and 5-hydroxytryptamine mechanism in inhibition of harmaline-induced tremors in rats. ( Paul, V, 1986) |
| " As regards behavioural effects, tremor induced by quipazine was present from the first postnatal day and was antagonized by methysergide, but not by p-chlorophenylalanine (PCPA) or pretreatment with 5,7-dihydroxytryptamine (5,7-DHT)." | 3.67 | Drug-induced activation of the inferior olivary nucleus in young rabbits. Differential effects of harmaline and quipazine. ( Barragan, LA; Delhaye-Bouchaud, N; Laget, P, 1985) |
| "Alterations of steady state and metabolism of putative neurotransmitters were studied in the brain of rats with a sustained tremor evoked by nicotine and pilocarpine." | 3.66 | Possible mechanisms of sustained tremor induction by nicotine in pilocarpine treated animals. ( Dohi, T; Tsujimoto, A, 1978) |
| "Amantadine-induced tremor has been investigated using mice." | 3.65 | Amantadin e tremor, a 5-hydroxytryptamine-mediated response? ( Cox, B; Tha, SJ, 1975) |
| "Oxotremorine did not alter the level of 5-HT and 5-hydroxyindoleacetic acid in different brain regions." | 3.65 | Serotonin content in the central nervous system of rats and cholinergic tremor. ( Funk, KF; Oelszner, W; Staib, AH; Westermann, KH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (68.75) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kunisawa, N | 1 |
| Iha, HA | 1 |
| Nomura, Y | 1 |
| Onishi, M | 1 |
| Matsubara, N | 1 |
| Shimizu, S | 1 |
| Ohno, Y | 1 |
| Mehta, H | 2 |
| Saravanan, KS | 1 |
| Mohanakumar, KP | 2 |
| Lin-Shiau, SY | 1 |
| Hsu, KS | 1 |
| Thomas, B | 1 |
| Cox, B | 1 |
| Tha, SJ | 1 |
| Oelszner, W | 1 |
| Funk, KF | 1 |
| Staib, AH | 1 |
| Westermann, KH | 1 |
| Silvestrini, B | 1 |
| Lisciani, R | 1 |
| Dohi, T | 1 |
| Tsujimoto, A | 1 |
| Messiha, FS | 1 |
| Paul, V | 1 |
| Barragan, LA | 1 |
| Delhaye-Bouchaud, N | 1 |
| Laget, P | 1 |
| Jacobs, BL | 1 |
| Peters, DA | 1 |
| Hrdina, PD | 1 |
| Singhal, RL | 1 |
| Ling, GM | 1 |
| Gumulka, W | 1 |
| Kostowski, W | 1 |
| Czlonkowski, A | 1 |
| Omori, K | 1 |
| Kojima, T | 1 |
| Kelly, DM | 1 |
| Naylor, RJ | 1 |
16 other studies available for fenclonine and Action Tremor
| Article | Year |
|---|---|
Serotonergic modulation of nicotine-induced kinetic tremor in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Fenclonine; Humans; Male; Mice; Nicot | 2017 |
Serotonin synthesis inhibition in olivo-cerebellar system attenuates harmaline-induced tremor in Swiss albino mice.
Topics: Animals; Behavior, Animal; Brain Chemistry; Cerebellum; Chromatography, High Pressure Liquid; Dopami | 2003 |
Modification of 2,2',2''-tripyridine-induced tremor in mice by serotonergic agonists and antagonists and benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Chelating Agents; Fenclonine; Injec | 1994 |
Effects of p-chlorophenylalanine on striatal acetylcholinesterase activity and on biogenic amine levels in nuclei raphe and caudate-putamen during physostigmine-induced tremor in rats.
Topics: Acetylcholinesterase; Animals; Biogenic Amines; Cholinesterase Inhibitors; Dopamine; Fenclonine; Neo | 2001 |
Amantadin e tremor, a 5-hydroxytryptamine-mediated response?
Topics: Amantadine; Animals; Brain; Brain Chemistry; Fenclonine; Hydroxyindoleacetic Acid; Mice; Mice, Inbre | 1975 |
Serotonin content in the central nervous system of rats and cholinergic tremor.
Topics: Animals; Brain; Brain Chemistry; Female; Fenclonine; Hydroxyindoleacetic Acid; Oxotremorine; Parasym | 1975 |
Experimental data suggesting an adrenergic mechanism in the production of parkinsonian symptoms.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Clonidine; Female; Fenclonine; Imipramine; Male; Mice; Mice, | 1976 |
Possible mechanisms of sustained tremor induction by nicotine in pilocarpine treated animals.
Topics: Animals; Brain; Corpus Striatum; Dopamine; Fenclonine; Hemicholinium 3; Homovanillic Acid; Hydroxyin | 1978 |
Effect of tremorogenic and antitumor agents on enzymes regulating a minor metabolic pathway of biogenic amines: an hypothesis for the underlying mechanism.
Topics: Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Antineoplastic Agents; Biogenic Amines; Fenc | 1991 |
Involvement of beta 2-adrenoceptor blockade and 5-hydroxytryptamine mechanism in inhibition of harmaline-induced tremors in rats.
Topics: 5-Hydroxytryptophan; Acebutolol; Adrenergic beta-Antagonists; Alkaloids; Animals; Butoxamine; Female | 1986 |
Drug-induced activation of the inferior olivary nucleus in young rabbits. Differential effects of harmaline and quipazine.
Topics: 5,7-Dihydroxytryptamine; Alkaloids; Animals; Dose-Response Relationship, Drug; Electrophysiology; Ex | 1985 |
Evidence for the functional interaction of two central neurotransmitters.
Topics: Anilides; Animals; Behavior, Animal; Cinnamates; Dopamine; Dopamine Antagonists; Drug Interactions; | 1974 |
The role of brain serotonin in DDT-induced hyperpyrexia.
Topics: Animals; Brain; Brain Stem; DDT; Fenclonine; Fever; Fluorine; Hydroxyindoleacetic Acid; Male; Pargyl | 1972 |
Role of 5-HT in the action of some drugs affecting extrapyramidal system.
Topics: Amphetamine; Animals; Brain; Catalepsy; Chlorpromazine; Electrodes; Extrapyramidal Tracts; Female; F | 1973 |
Effect of L-5HTP on tremorine- or oxotremorine-induced tremor in mice and rats.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Drug Synergism; Fenclonine; Male; Mice; Oxotremorine; Rats; | 1973 |
Mechanisms of tremor induction by harmine.
Topics: 5-Hydroxytryptophan; Alkaloids; Animals; Biogenic Amines; Depression, Chemical; Dopamine; Dose-Respo | 1974 |