fenbufen has been researched along with Arthritis, Rheumatoid in 28 studies
fenbufen: structure; RN given refers to parent cpd
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fenbufen and indomethacin were compared in the treatment of 30 patients with rheumatoid arthritis." | 9.05 | Fenbufen and indomethacin: a comparative study in rheumatoid arthritis. ( Burton, WD; Hazleman, BL, 1983) |
| "Fenbufen (Cinopal) has been evaluated extensively in 155 clinical trials, including 102 in rheumatoid arthritis and 53 in osteoarthritis." | 9.05 | Overview of efficacy of fenbufen in rheumatoid arthritis and osteoarthritis. ( Bernstein, J, 1983) |
| "Fenbufen (3(4-biphenyl-carbonyl) propionic acid) (Cinopal; Lederle) was administered as a single daily dose of 1000 mg for 4 weeks to 20 patients with rheumatoid arthritis." | 9.05 | Fenbufen as a single daily dose in the treatment of rheumatoid arthritis. ( Finegan, K; Solomon, L, 1981) |
| "25 out-patients with active classical or definite adult-onset rheumatoid arthritis were enrolled in a 4-week randomized, two-period double-blind cross-over study comparing gamma-oxo(1,1'-biphenyl)-4-butanoic acid (fenbufen) (1000 mg/d) and acetylsalicylic acid (ASA) (3600 mg/d)." | 9.05 | Double blind cross-over trial comparing fenbufen and acetylsalicylic acid in rheumatoid arthritis. ( Anderson, LG; Bina, PR, 1980) |
| "A short-term, double-blind crossover study was completed in 29 patients with definite rheumatoid arthritis to compare the antirheumatic activity of indomethacin (100 mg/day) with that of fenbufen (800 mg/day)." | 9.04 | A comparative study of fenbufen and indomethacin in patients with rheumatoid arthritis. ( Deodhar, SD; Sethi, R, 1979) |
| "Pure red cell aplasia occurred after fenbufen administration in a patient with severe rheumatoid arthritis." | 7.67 | Fenbufen induced pure red cell aplasia in rheumatoid arthritis. ( Baron, S; Blum, I; Michalevicz, R, 1987) |
| "The fenbufen-treated group showed significant improvement in four parameters: pain at rest, pain on movement, duration of pain, and number of swollen joints." | 6.65 | A six-month parallel group comparison of fenbufen and naproxen in the treatment of rheumatoid arthritis. ( Khan, FM, 1983) |
| "Fenbufen and indomethacin were compared in the treatment of 30 patients with rheumatoid arthritis." | 5.05 | Fenbufen and indomethacin: a comparative study in rheumatoid arthritis. ( Burton, WD; Hazleman, BL, 1983) |
| "Fenbufen (Cinopal) has been evaluated extensively in 155 clinical trials, including 102 in rheumatoid arthritis and 53 in osteoarthritis." | 5.05 | Overview of efficacy of fenbufen in rheumatoid arthritis and osteoarthritis. ( Bernstein, J, 1983) |
| "Fenbufen (3(4-biphenyl-carbonyl) propionic acid) (Cinopal; Lederle) was administered as a single daily dose of 1000 mg for 4 weeks to 20 patients with rheumatoid arthritis." | 5.05 | Fenbufen as a single daily dose in the treatment of rheumatoid arthritis. ( Finegan, K; Solomon, L, 1981) |
| "25 out-patients with active classical or definite adult-onset rheumatoid arthritis were enrolled in a 4-week randomized, two-period double-blind cross-over study comparing gamma-oxo(1,1'-biphenyl)-4-butanoic acid (fenbufen) (1000 mg/d) and acetylsalicylic acid (ASA) (3600 mg/d)." | 5.05 | Double blind cross-over trial comparing fenbufen and acetylsalicylic acid in rheumatoid arthritis. ( Anderson, LG; Bina, PR, 1980) |
| "A short-term, double-blind crossover study was completed in 29 patients with definite rheumatoid arthritis to compare the antirheumatic activity of indomethacin (100 mg/day) with that of fenbufen (800 mg/day)." | 5.04 | A comparative study of fenbufen and indomethacin in patients with rheumatoid arthritis. ( Deodhar, SD; Sethi, R, 1979) |
| "Pure red cell aplasia occurred after fenbufen administration in a patient with severe rheumatoid arthritis." | 3.67 | Fenbufen induced pure red cell aplasia in rheumatoid arthritis. ( Baron, S; Blum, I; Michalevicz, R, 1987) |
| "Male and female patients suffering from rheumatoid arthritis with normal renal function or with renal impairment were treated in hospital with 300 mg of fenbufen 8 hourly for fourteen days." | 3.66 | A study of repeated administration of fenbufen in patients with chronic rheumatic disorders and renal impairment. ( Armstrong, R; Bradbrook, I; Gibson, TJ; Morrison, P; Rogers, HJ; Spector, RG, 1982) |
| "The fenbufen-treated group showed significant improvement in four parameters: pain at rest, pain on movement, duration of pain, and number of swollen joints." | 2.65 | A six-month parallel group comparison of fenbufen and naproxen in the treatment of rheumatoid arthritis. ( Khan, FM, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (96.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dhaneshwar, S | 1 |
| Kusurkar, M | 1 |
| Bodhankar, S | 1 |
| Bihani, G | 1 |
| Burton, WD | 1 |
| Hazleman, BL | 1 |
| Khan, FM | 1 |
| Bernstein, J | 1 |
| Mizushima, Y | 2 |
| Soldati, R | 2 |
| Sorbilli, G | 2 |
| Di Benedetto, P | 2 |
| Becker, A | 1 |
| Hoffmeister, RT | 1 |
| Mawdsley, P | 1 |
| Solomon, L | 1 |
| Finegan, K | 1 |
| Iseki, F | 1 |
| Armstrong, R | 2 |
| Bradbrook, I | 2 |
| Gibson, TJ | 1 |
| Morrison, P | 2 |
| Rogers, HJ | 1 |
| Spector, RG | 1 |
| Paice, EW | 1 |
| Tookman, AJ | 1 |
| White, AG | 1 |
| Brock, PG | 1 |
| Jackson, D | 1 |
| Spector, R | 1 |
| Gibson, T | 1 |
| Rogers, H | 1 |
| Roth, SH | 1 |
| Cryan, WS | 1 |
| Harris, BK | 1 |
| Klipper, AR | 1 |
| Kolodny, LA | 1 |
| Rochmis, PG | 1 |
| Schwartz, HA | 1 |
| Virshup, AM | 1 |
| Urdaneta, E | 1 |
| Bonnelli, J | 1 |
| Curiel, HE | 1 |
| Soria, G | 1 |
| Anderson, LG | 1 |
| Bina, PR | 1 |
| Accardo, S | 1 |
| Barisone, G | 1 |
| Samantà , E | 1 |
| Buffrini, L | 1 |
| Zecchino, MM | 1 |
| Deodhar, SD | 1 |
| Sethi, R | 1 |
| Marcolongo, R | 1 |
| Coppi, R | 1 |
| Zannella, F | 1 |
| Tuzi, T | 1 |
| Schiavetti, L | 1 |
| De Salcedo, I | 1 |
| Michalevicz, R | 1 |
| Baron, S | 1 |
| Blum, I | 1 |
| Spiegel, TM | 1 |
| King, W | 1 |
| Weiner, SR | 1 |
| Paulus, HE | 1 |
| Pullar, T | 1 |
| Zoma, AA | 1 |
| Madhok, R | 1 |
| Hunter, JA | 1 |
| Capell, HA | 1 |
14 trials available for fenbufen and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Fenbufen and indomethacin: a comparative study in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind | 1983 |
A six-month parallel group comparison of fenbufen and naproxen in the treatment of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Fema | 1983 |
Overview of efficacy of fenbufen in rheumatoid arthritis and osteoarthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Humans; Indometh | 1983 |
Pro-drugs of non-steroidal anti-inflammatory agents.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Gast | 1983 |
Fenbufen, a new non-steroidal anti-inflammatory agent in rheumatoid arthritis, its efficacy and toxicity.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Biphenyl Compounds; Clinical Trials as | 1980 |
A survey of clinical trials with fenbufen.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Biphenyl Compounds; Clinical Trials as Topic; Femal | 1980 |
Fenbufen as a single daily dose in the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Biphenyl Compounds; Clinical Trials as | 1981 |
Fenbufen in arthritis. A report from the General Practitioner Research Group.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Ost | 1981 |
Long-term clinical studies of fenbufen in Japan.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Metho | 1982 |
Double blind cross-over trial comparing fenbufen and acetylsalicylic acid in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Biphenyl Compounds; Double-Bl | 1980 |
A comparative study of fenbufen and indomethacin in patients with rheumatoid arthritis.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biphenyl Compound | 1979 |
[Double-blind cross-over clinical study of the effectiveness and tolerability of fenbufen versus ibuprofen in the therapy of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Biphenyl Compounds; Double-Blind Method; Drug Evaluation; Female | 1979 |
Fenbufen--a new nonsteroidal anti-inflammatory agent: comparison with phenylbutazone in rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Biphenyl Compounds; Clinical Trials as Topic | 1975 |
Have the newer NSAIDS contributed to the management of rheumatoid arthritis?
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; Feprazone; Flurbiprofen; Human | 1985 |
14 other studies available for fenbufen and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Carrier-linked mutual prodrugs of biphenylacetic acid as a promising alternative to bioprecursor fenbufen: design, kinetics, and pharmacological studies.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Exper | 2014 |
[Long-term comparative study of fenbufen and aspirin in patients with rheumatoid arthritis].
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthriti | 1980 |
A study of repeated administration of fenbufen in patients with chronic rheumatic disorders and renal impairment.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chronic Disease; Female; Humans; Kidne | 1982 |
Fenbufen in patients with gastric intolerance.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Tolerance; Female; Humans; Peptic | 1982 |
UK general practitioners experience of fenbufen in elderly patients.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Interactions; Family Practice; Female; Humans; | 1982 |
Basic and clinical studies of prodrugs of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Biotransformation; Humans; Indome | 1982 |
Study of repeated administration of fenbufen in patients with chronic rheumatic disorders and renal impairment.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chronic Disease; Female; Humans; Kidne | 1982 |
Long-term double-blind comparison of fenbufen with aspirin in the treatment of rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Double-Blind Meth | 1982 |
Long-term clinical evaluation of fenbufen in the treatment of rheumatoid arthritis and osteoarthritis: Latin-American experience.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Female; Humans; Latin America; Male; Middle | 1982 |
[Open clinical study of the use of 3-(4-biphenylcarbonyl) propionic acid in rheumatoid arthritis and arthrosis].
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Biphenyl Compounds; Female; Humans; Ma | 1981 |
[Clinical study of long term administration of fenbufen in rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Biphenyl Compounds; Female; Humans; Male; Middle Aged; Phenylbut | 1980 |
[Particular aspect of the drug therapy of rheumatoid arthritis: fenbufen and morning stiffness].
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Biphenyl Compounds; Drug Evaluation; F | 1978 |
Fenbufen induced pure red cell aplasia in rheumatoid arthritis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bone Marrow | 1987 |
Measuring disease activity: comparison of joint tenderness, swelling, and ultrasonography in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Phenylbutyrates; Propionates; Prospective Studies; Ultrasonics; Wrist | 1987 |