fenbufen has been researched along with Adjuvant Arthritis in 6 studies
fenbufen: structure; RN given refers to parent cpd
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred analogs of fenbufen were prepared and tested using the carrageenan, polyarthritis, and UV erythema anti-inflammatory tests and the 2-phenyl-1,4-benzoquinone writhing and inflamed paw pressure analgesic tests." | 3.65 | Fenbufen, a new anti-inflammatory analgesic: synthesis and structure-activity relationships of analogs. ( Child, RG; Osterberg, AC; Sloboda, AE; Tomcufcik, AS, 1977) |
| "Fenbufen thus appears to be a pro-drug capable of circumventing at least some of the gastric toxicity usually incurred when compounds, which are themselves capable of inhibiting PG synthesis, are introduced directly into the stomach." | 2.36 | The pharmacological properties of fenbufen. A review. ( Osterberg, AC; Panagides, J; Sloboda, AE; Tolman, EL, 1980) |
| "In the model of adjuvant arthritis VUFB-16066 improves most of disease symptoms including immunopathological disturbances, which indicates possible disease-modifying activity of the drug." | 1.30 | Pharmacological profile of the novel potent antirheumatic 4-(2',4'-difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic acid. ( Andĕrova, E; Jandera, A; Kuchar, M; Panajotova, V, 1997) |
| " In addition, dose-response derived potencies show fenbufen more potent than ASA and at least as potent as phenylbutazone in all five tests." | 1.26 | A new non-steroidal anti-inflammatory analgesic: gamma-oxo (1,1'-biphenyl)-4-butanoic acid (fenbufen). Chemistry and activity of analogs. ( Child, RG; Osterberg, AC; Sloboda, AE; Tomcufcik, AS, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maryanoff, BE | 1 |
| Keeley, SL | 1 |
| Persico, FJ | 1 |
| Dhaneshwar, S | 1 |
| Kusurkar, M | 1 |
| Bodhankar, S | 1 |
| Bihani, G | 1 |
| Sloboda, AE | 3 |
| Tolman, EL | 1 |
| Osterberg, AC | 3 |
| Panagides, J | 1 |
| Child, RG | 2 |
| Tomcufcik, AS | 2 |
| Panajotova, V | 1 |
| Andĕrova, E | 1 |
| Jandera, A | 1 |
| Kuchar, M | 1 |
1 review available for fenbufen and Adjuvant Arthritis
| Article | Year |
|---|---|
The pharmacological properties of fenbufen. A review.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, E | 1980 |
5 other studies available for fenbufen and Adjuvant Arthritis
| Article | Year |
|---|---|
Replacement of aromatic or heteroaromatic groups in nonsteroidal antiinflammatory agents with the ferrocene group.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Blood Platelets; Female; Ferrous Compoun | 1983 |
Carrier-linked mutual prodrugs of biphenylacetic acid as a promising alternative to bioprecursor fenbufen: design, kinetics, and pharmacological studies.
Topics: Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Exper | 2014 |
A new non-steroidal anti-inflammatory analgesic: gamma-oxo (1,1'-biphenyl)-4-butanoic acid (fenbufen). Chemistry and activity of analogs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Biphenyl Compounds; Carrageenan | 1980 |
Pharmacological profile of the novel potent antirheumatic 4-(2',4'-difluorobiphenyl-4-yl)-2-methyl-4-oxobutanoic acid.
Topics: Abdominal Pain; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Art | 1997 |
Fenbufen, a new anti-inflammatory analgesic: synthesis and structure-activity relationships of analogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Biphenyl Compoun | 1977 |