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fenbendazole and Trichostrongylosis

fenbendazole has been researched along with Trichostrongylosis in 34 studies

Fenbendazole: Antinematodal benzimidazole used in veterinary medicine.
fenbendazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted at positons 2 and 5 by (methoxycarbonyl)amino and phenylsulfanediyl groups, respectively. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.

Trichostrongylosis: Infestation with nematode worms of the genus TRICHOSTRONGYLUS. Man and animals become infected by swallowing larvae, usually with contaminated food or drink, although the larvae may penetrate human skin.

Research Excerpts

ExcerptRelevanceReference
" It is concluded that dosing sheep with D."1.30The preventive effect of the fungus Duddingtonia flagrans on trichostrongyle infections of lambs on pasture. ( Githigia, SM; Kyvsgaard, NC; Larsen, M; Nansen, P; Thamsborg, SM, 1997)
"Oxfendazole, fenbendazole and albendazole were each administered at 5mgkg(-1) to sheep fitted with abomasal cannulae as a single bolus intra-ruminally or infused intra-abomasally at a declining exponential rate, with half-life equivalent to the rate of rumen fluid outflow."1.30Influence of ruminal bypass on the pharmacokinetics and efficacy of benzimidazole anthelmintics in sheep. ( Hennessy, DR; Steel, JW, 1999)
" The Cmax for all the metabolites was higher in the BZ-sensitive O."1.29The influence of a heavy infection with sensitive and resistant strains of Ostertagia circumcincta and with Trichostrongylus colubriformis on the pharmacokinetics of febantel in lambs. ( Debackere, M; Landuyt, J; McKellar, Q; Vercruysse, J, 1995)
" The influence of the host's physiology on the reduced bioavailability of fenbendazole is discussed."1.29Influence of subclinical nematodosis on the kinetic disposition of fenbendazole in buffaloes. ( Mathur, AC; Sanyal, PK; Sarkar, S, 1995)
" In order to determine a more complete pharmacokinetic profile, febantel was injected intravenously at a dose of 2."1.29The influence of Ostertagia circumcincta and Trichostrongylus colubriformis infections on the pharmacokinetics of febantel in lambs. ( Debackere, M; Landuyt, J; McKellar, Q; Vercruysse, J, 1993)
" Group-1 calves were treated with ivermectin (200 micrograms/kg of body weight, SC) at approximately 6-week intervals for a total of 8 treatments; group-2 calves were given the same dosage of ivermectin by the same route of administration as group-1 calves in November, March, and July; group-3 calves were given fenbendazole paste (5 mg/kg, PO) at the same times as group-2 calves; and group-4 calves served as untreated controls with provision for ivermectin salvage treatment."1.28Effects of ivermectin and fenbendazole in strategic treatment of gastrointestinal nematode infections in cattle. ( Barras, SA; Hawkins, JA; Knox, JW; Williams, JC, 1990)
" colubriformis for 10 weeks, dosed with fenbendazole and given no further larvae."1.27Chronic infections with Trichostrongylus colubriformis in lambs: influence of anthelmintic treatment on intestinal morphology and mucosal cell populations. ( Angus, KW; Coop, RL, 1984)
"Fenbendazole (FBZ) was continuously infused for 30 days into the rumen of 103 lambs which had mature or developing benzimidazole-susceptible or thiabendazole-resistant Haemonchus contortus and susceptible Trichostrongylus colubriformis infections."1.27Anthelmintic activity of continuous low doses of fenbendazole into the rumen of sheep. ( Boisvenue, RJ; Colestock, EL; Hendrix, JC, 1988)
" With all dosage groups considered, Strongyloides and Nematodirus eggs were most sensitive to treatment, with 100% reductions in fecal egg counts."1.27Efficacy of fenbendazole for endoparasite control in large herds of nondomestic ruminants. ( Janssen, DL, 1985)
"Sixteen sheep which had previously been infected with Ostertagia circumcincta were dosed with 4000 Trichostrongylus colubriformis larvae/day for four weeks, then given anthelmintic and killed at intervals thereafter."1.26The rate of recovery of intestinal morphology following anthelmintic treatment of parasitised sheep. ( Angus, KW; Coop, RL; Sykes, AR, 1979)
"Fenbendazole was more effective against both strains following intra-ruminal administration."1.26The effect of route of administration on the anthelmintic efficacy of benzimidazole anthelmintics in sheep infected with strains of Haemonchus contortus and Trichostrongylus colubriformis resistant or susceptible to thiabendazole. ( Campbell, NJ; Hall, CA; Kelly, JD; Martin, IC; Thompson, HG; Whitlock, HV, 1977)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199017 (50.00)18.7374
1990's14 (41.18)18.2507
2000's0 (0.00)29.6817
2010's2 (5.88)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Ezenwa, VO1
Budischak, SA1
Buss, P1
Seguel, M1
Luikart, G1
Jolles, AE1
Sakamoto, K1
Peña-Espinoza, M1
Thamsborg, SM2
Demeler, J1
Enemark, HL1
Adam, A1
Webster, LM1
Mullen, W1
Keller, LF1
Johnson, PC1
Angus, KW3
Coop, RL3
Hutchison, G1
Wright, S1
Panitz, E1
Shum, KL1
Landuyt, J2
Debackere, M2
Vercruysse, J2
McKellar, Q2
Mathur, AC1
Sanyal, PK1
Sarkar, S1
Hunt, KR1
Hong, C1
Coles, GC1
Jones, TO1
Kochapakdee, S1
Pandey, VS1
Pralomkarn, W1
Choldumrongkul, S1
Ngampongsai, W1
Lawpetchara, A1
Hoste, H2
Mallet, S1
Koch, C1
Soccol, VT1
Sotomaior, C1
Souza, FP1
Castro, EA1
Pessôa Silva, MC1
Milczewski, V1
Patterson, DM1
Jackson, F1
Huntley, JF1
Stevenson, LM1
Jones, DG1
Jackson, E1
Russel, AJ1
Bauer, C1
Holtemöller, H1
Schmid, K1
Githigia, SM1
Larsen, M1
Kyvsgaard, NC1
Nansen, P1
Chartier, C1
Steel, JW1
Hennessy, DR1
Crowley, JW1
Foreyt, WJ1
Bliss, DH1
Todd, AC1
Romaniuk, K1
Sykes, AR1
Sangster, NC2
Whitlock, HV3
Kelly, JD3
Gunawan, M2
Hall, CA2
Griffin, D1
Thompson, HG1
Campbell, NJ1
Martin, IC1
Kirsch, R1
Maingi, N1
Williams, JC1
Knox, JW1
Barras, SA1
Hawkins, JA1
Boisvenue, RJ1
Colestock, EL1
Hendrix, JC1
Anderson, N1
Martin, PJ1
Jarrett, RG1
Waller, PJ1
Donnelly, JR1
Dobson, RJ1
Donald, AD1
Axelsen, A1
Morley, FH1
Entrocasso, CM2
Parkins, JJ2
Armour, J2
Bairden, K2
McWilliam, PN2
Pullman, AL1
Ford, GE1
Janssen, DL1

Trials

1 trial available for fenbendazole and Trichostrongylosis

ArticleYear
Occurrence of resistance to anthelmintics in sheep in Paraná State, Brazil.
    The Veterinary record, 1996, Oct-26, Volume: 139, Issue:17

    Topics: Albendazole; Animals; Anthelmintics; Brazil; Drug Resistance, Multiple; Feces; Fenbendazole; Haemonc

1996

Other Studies

33 other studies available for fenbendazole and Trichostrongylosis

ArticleYear
Natural resistance to worms exacerbates bovine tuberculosis severity independently of worm coinfection.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 01-19, Volume: 118, Issue:3

    Topics: Animals; Antinematodal Agents; Buffaloes; Cattle; Coinfection; Disease Progression; Disease Resistan

2021
Field efficacy of four anthelmintics and confirmation of drug-resistant nematodes by controlled efficacy test and pyrosequencing on a sheep and goat farm in Denmark.
    Veterinary parasitology, 2014, Dec-15, Volume: 206, Issue:3-4

    Topics: Animals; Anthelmintics; Benzimidazoles; Denmark; Drug Resistance; Female; Fenbendazole; Goat Disease

2014
Quantifying fenbendazole and its metabolites in self-medicating wild red grouse Lagopus lagopus scoticus using an HPLC-MS-MS approach.
    Veterinary parasitology, 2011, May-11, Volume: 177, Issue:3-4

    Topics: Animals; Antinematodal Agents; Bird Diseases; Chromatography, High Pressure Liquid; Fenbendazole; Ga

2011
Chronic infections with Trichostrongylus colubriformis in lambs: influence of anthelmintic treatment on intestinal morphology and mucosal cell populations.
    Journal of comparative pathology, 1984, Volume: 94, Issue:3

    Topics: Animals; Benzimidazoles; Chronic Disease; Female; Fenbendazole; Intestinal Diseases, Parasitic; Inte

1984
Effect of anthelmintic treatment on the productivity of lambs infected with the intestinal nematode, Trichostrongylus colubriformis.
    Research in veterinary science, 1984, Volume: 36, Issue:1

    Topics: Animals; Benzimidazoles; Body Weight; Female; Fenbendazole; Intestinal Diseases, Parasitic; Male; Ph

1984
Efficacy of four anthelmintics in Trichostrongylus axei or T. colubriformis infections in the gerbil, Meriones unguiculatus.
    The Journal of parasitology, 1981, Volume: 67, Issue:1

    Topics: Animals; Benzimidazoles; Cambendazole; Drug Evaluation, Preclinical; Female; Fenbendazole; Gerbillin

1981
The influence of a heavy infection with sensitive and resistant strains of Ostertagia circumcincta and with Trichostrongylus colubriformis on the pharmacokinetics of febantel in lambs.
    Journal of veterinary pharmacology and therapeutics, 1995, Volume: 18, Issue:3

    Topics: Administration, Oral; Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Feces; Fenbendazole;

1995
Influence of subclinical nematodosis on the kinetic disposition of fenbendazole in buffaloes.
    Veterinary research communications, 1995, Volume: 19, Issue:1

    Topics: Ancylostomatoidea; Animals; Buffaloes; Cattle; Cattle Diseases; Fenbendazole; Hookworm Infections; M

1995
Benzimidazole-resistant Trichostrongylus colubriformis from goats in central England.
    The Veterinary record, 1994, Apr-16, Volume: 134, Issue:16

    Topics: Animals; Drug Resistance; England; Feces; Fenbendazole; Goat Diseases; Goats; Levamisole; Parasite E

1994
The influence of Ostertagia circumcincta and Trichostrongylus colubriformis infections on the pharmacokinetics of febantel in lambs.
    Journal of veterinary pharmacology and therapeutics, 1993, Volume: 16, Issue:3

    Topics: Administration, Oral; Animals; Anthelmintics; Benzimidazoles; Biological Availability; Chromatograph

1993
Anthelmintic resistance in goats in southern Thailand.
    The Veterinary record, 1995, Jul-29, Volume: 137, Issue:5

    Topics: Albendazole; Animals; Anthelmintics; Drug Resistance; Feces; Fenbendazole; Goat Diseases; Goats; Hae

1995
Trichostrongylus colubriformis infection in rabbits: persistence of the distal adaptive response to parasitism after anthelmintic treatment.
    Journal of comparative pathology, 1995, Volume: 113, Issue:2

    Topics: Adaptation, Physiological; Alkaline Phosphatase; Animals; Antinematodal Agents; Fenbendazole; Intest

1995
The response of breeding doses to nematodiasis: segregation into "responders" and "non-responders".
    International journal for parasitology, 1996, Volume: 26, Issue:11

    Topics: Animal Feed; Animals; Anthelmintics; Breeding; Fenbendazole; Goat Diseases; Goats; Larva; Leukocyte

1996
Field evaluation of a fenbendazole slow release bolus in the control of nematode infections in first-season cattle.
    The Veterinary record, 1997, Apr-12, Volume: 140, Issue:15

    Topics: Animals; Antinematodal Agents; Cattle; Cattle Diseases; Delayed-Action Preparations; Dictyocaulus; D

1997
The preventive effect of the fungus Duddingtonia flagrans on trichostrongyle infections of lambs on pasture.
    International journal for parasitology, 1997, Volume: 27, Issue:8

    Topics: Animals; Anthelmintics; Denmark; Feces; Fenbendazole; Larva; Mitosporic Fungi; Ostertagiasis; Parasi

1997
Response to challenge infection with Haemonchus contortus and Trichostrongylus colubriformis in dairy goats. Consequences on milk production.
    Veterinary parasitology, 1998, Jan-15, Volume: 74, Issue:1

    Topics: Analysis of Variance; Animals; Antinematodal Agents; Female; Fenbendazole; Goat Diseases; Goats; Hae

1998
Influence of ruminal bypass on the pharmacokinetics and efficacy of benzimidazole anthelmintics in sheep.
    International journal for parasitology, 1999, Volume: 29, Issue:2

    Topics: Abomasum; Albendazole; Animals; Antinematodal Agents; Benzimidazoles; Drug Resistance; Fenbendazole;

1999
Further controlled evaluations of fenbendazole as a bovine anthelmintic.
    American journal of veterinary research, 1977, Volume: 38, Issue:5

    Topics: Animal Feed; Animals; Benzimidazoles; Cattle; Cattle Diseases; Dictyocaulus Infections; Drug Evaluat

1977
[Control of monieziasis and gastrointestinal and pulmonary threadworms in sheep with fenbendazole].
    Wiadomosci parazytologiczne, 1979, Volume: 25, Issue:4

    Topics: Animals; Benzimidazoles; Dictyocaulus Infections; Fenbendazole; Gastrointestinal Diseases; Helminthi

1979
The rate of recovery of intestinal morphology following anthelmintic treatment of parasitised sheep.
    Research in veterinary science, 1979, Volume: 26, Issue:1

    Topics: Animals; Benzimidazoles; Fenbendazole; Intestine, Small; Sheep; Sheep Diseases; Trichostrongyloidias

1979
The effect of single and divided dose administration on the efficacy of fenbendazole against adult stages of benzimidazole resistant sheep trichostrongylids.
    Research in veterinary science, 1979, Volume: 26, Issue:1

    Topics: Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Fenbendazole; Haemonchiasis; Haemonchus; Ma

1979
The efficacy of fenbendazole and albendazole against immature and adult stages of benzimidazole-resistant sheep trichostrongylids.
    Research in veterinary science, 1979, Volume: 27, Issue:1

    Topics: Animals; Benzimidazoles; Drug Resistance; Female; Fenbendazole; Haemonchiasis; Male; Sheep; Sheep Di

1979
The effect of route of administration on the anthelmintic efficacy of benzimidazole anthelmintics in sheep infected with strains of Haemonchus contortus and Trichostrongylus colubriformis resistant or susceptible to thiabendazole.
    Research in veterinary science, 1977, Volume: 22, Issue:2

    Topics: Abomasum; Administration, Oral; Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Female; Fen

1977
In vitro and in vivo studies on the ovicidal activity of fenbendazole.
    Research in veterinary science, 1978, Volume: 25, Issue:3

    Topics: Animals; Benzimidazoles; Fenbendazole; Haemonchiasis; Haemonchus; Sheep; Sheep Diseases; Trichostron

1978
Resistance to thiabendazole, fenbendazole and levamisole in Haemonchus and Trichostrongylus species in sheep on a Kenyan farm.
    Veterinary parasitology, 1991, Volume: 39, Issue:3-4

    Topics: Animals; Drug Resistance; Feces; Fenbendazole; Haemonchiasis; Haemonchus; Intestinal Diseases, Paras

1991
Effects of ivermectin and fenbendazole in strategic treatment of gastrointestinal nematode infections in cattle.
    American journal of veterinary research, 1990, Volume: 51, Issue:12

    Topics: Animals; Cattle; Cattle Diseases; Fenbendazole; Haemonchiasis; Ivermectin; Male; Ostertagiasis; Para

1990
Anthelmintic activity of continuous low doses of fenbendazole into the rumen of sheep.
    Veterinary parasitology, 1988, Volume: 26, Issue:3-4

    Topics: Animals; Benzimidazoles; Female; Fenbendazole; Haemonchiasis; Haemonchus; Male; Rumen; Sheep; Sheep

1988
Mixtures of anthelmintics: a strategy against resistance.
    Australian veterinary journal, 1988, Volume: 65, Issue:2

    Topics: Animals; Anthelmintics; Drug Resistance; Drug Therapy, Combination; Fenbendazole; Levamisole; Morant

1988
Effects of helminth infection on the pre-weaning production of ewes and lambs: evaluation of pre- and post-lambing drenching and provision of safe lambing pasture.
    Australian veterinary journal, 1987, Volume: 64, Issue:11

    Topics: Animals; Body Weight; Cattle; Feces; Female; Fenbendazole; Helminthiasis; Helminthiasis, Animal; Lev

1987
Metabolism and growth in housed calves given a morantel sustained release bolus and exposed to natural trichostrongyle infection.
    Research in veterinary science, 1986, Volume: 40, Issue:1

    Topics: Aging; Animal Feed; Animals; Benzimidazoles; Body Weight; Cattle; Cattle Diseases; Delayed-Action Pr

1986
Production, parasitological and carcase evaluation studies in steers exposed to trichostrongyle infection and treated with a morantel bolus or fenbendazole in two consecutive grazing seasons.
    Research in veterinary science, 1986, Volume: 40, Issue:1

    Topics: Animal Feed; Animals; Benzimidazoles; Cattle; Cattle Diseases; Delayed-Action Preparations; Fenbenda

1986
A prolonged summer anthelmintic treatment for prevention of growth reduction due to abomasal nematode parasitism in young beef cattle.
    Australian veterinary journal, 1985, Volume: 62, Issue:5

    Topics: Abomasum; Animals; Australia; Benzimidazoles; Body Weight; Cambendazole; Cattle; Cattle Diseases; Fe

1985
Efficacy of fenbendazole for endoparasite control in large herds of nondomestic ruminants.
    Journal of the American Veterinary Medical Association, 1985, Dec-01, Volume: 187, Issue:11

    Topics: Animal Population Groups; Animals; Animals, Wild; Artiodactyla; Benzimidazoles; Fenbendazole; Intest

1985