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fenbendazole and Haemonchiasis

fenbendazole has been researched along with Haemonchiasis in 50 studies

Fenbendazole: Antinematodal benzimidazole used in veterinary medicine.
fenbendazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted at positons 2 and 5 by (methoxycarbonyl)amino and phenylsulfanediyl groups, respectively. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.

Haemonchiasis: Infection with nematodes of the genus HAEMONCHUS, characterized by digestive abnormalities and anemia similar to that from hookworm infestation.

Research Excerpts

ExcerptRelevanceReference
"Thiabendazole was used more often (9 tests) than the other compounds."2.67Controlled tests of activity of several antiparasitic compounds against natural infections of Haemonchus contortus and other helminths in lambs from a flock established in 1962. ( Drudge, JH; Lyons, ET; Stamper, S; Tolliver, SC, 1993)
"When levamisole use was discontinued for 1 year, susceptibility to levamisole appeared to return."1.31Multiple anthelmintic resistance in a goat herd. ( Gipson, TA; Zajac, AM, 2000)
"Oxfendazole, fenbendazole and albendazole were each administered at 5mgkg(-1) to sheep fitted with abomasal cannulae as a single bolus intra-ruminally or infused intra-abomasally at a declining exponential rate, with half-life equivalent to the rate of rumen fluid outflow."1.30Influence of ruminal bypass on the pharmacokinetics and efficacy of benzimidazole anthelmintics in sheep. ( Hennessy, DR; Steel, JW, 1999)
" A pharmacokinetic dose titration study was carried out in sheep with fenbendazole (5 mg kg-1) and piperonyl butoxide administered orally at 0, 15, 31, 63, 125 and 250 mg kg-1."1.29Interaction between fenbendazole and piperonyl butoxide: pharmacokinetic and pharmacodynamic implications. ( Benchaoui, HA; McKellar, QA, 1996)
"Treatment with fenbendazole at the recommended dose of groups of lambs infected with either strains showed no reduction in the DASP strain and a 70."1.28Resistance to benzimidazoles in Haemonchus contortus of sheep in Tanzania. ( Bjørn, H; Kassuku, AA; Monrad, J; Nansen, P, 1990)
" Group-1 calves were treated with ivermectin (200 micrograms/kg of body weight, SC) at approximately 6-week intervals for a total of 8 treatments; group-2 calves were given the same dosage of ivermectin by the same route of administration as group-1 calves in November, March, and July; group-3 calves were given fenbendazole paste (5 mg/kg, PO) at the same times as group-2 calves; and group-4 calves served as untreated controls with provision for ivermectin salvage treatment."1.28Effects of ivermectin and fenbendazole in strategic treatment of gastrointestinal nematode infections in cattle. ( Barras, SA; Hawkins, JA; Knox, JW; Williams, JC, 1990)
"Fenbendazole (FBZ) was continuously infused for 30 days into the rumen of 103 lambs which had mature or developing benzimidazole-susceptible or thiabendazole-resistant Haemonchus contortus and susceptible Trichostrongylus colubriformis infections."1.27Anthelmintic activity of continuous low doses of fenbendazole into the rumen of sheep. ( Boisvenue, RJ; Colestock, EL; Hendrix, JC, 1988)
"Fenbedazole, dosed to artificially infested cattle at 7,5 mg/kg live mass, was more than 80% effective in more than 80% of the treated animals against immature and adult Haemonchus placei, Ostertagia ostertagi; Cooperia spp."1.26The efficacy of fenbendazole at a dosage rate of 7,5 mg/kg against nematode infestations in cattle. ( Malan, FS, 1979)
"Fenbendazole was more effective against both strains following intra-ruminal administration."1.26The effect of route of administration on the anthelmintic efficacy of benzimidazole anthelmintics in sheep infected with strains of Haemonchus contortus and Trichostrongylus colubriformis resistant or susceptible to thiabendazole. ( Campbell, NJ; Hall, CA; Kelly, JD; Martin, IC; Thompson, HG; Whitlock, HV, 1977)

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199017 (34.00)18.7374
1990's20 (40.00)18.2507
2000's5 (10.00)29.6817
2010's7 (14.00)24.3611
2020's1 (2.00)2.80

Authors

AuthorsStudies
Ezenwa, VO1
Budischak, SA1
Buss, P1
Seguel, M1
Luikart, G1
Jolles, AE1
Sakamoto, K1
Dixit, AK1
Das, G1
Dixit, P1
Sharma, RL1
Muchiut, SM1
Fernández, AS1
Lloberas, M1
Steffan, PE1
Luque, SE1
Cardozo, PA1
Bernat, GA1
Riva, E1
Fiel, CA1
Holm, SA1
Sörensen, CR1
Thamsborg, SM2
Enemark, HL2
Peña-Espinoza, M1
Demeler, J1
Vijayasarathi, MK1
Sreekumar, C1
Venkataramanan, R1
Raman, M1
Westers, T1
Jones-Bitton, A1
Menzies, P1
Van Leeuwen, J1
Poljak, Z1
Peregrine, AS1
Chiejina, SN2
Behnke, JM2
Musongong, GA2
Nnadi, PA2
Ngongeh, LA1
Garg, R1
Kumar, RR1
Yadav, CL5
Banerjee, PS1
Smith, WD1
Eysker, M3
Jansen, J2
Boersema, JH2
Lewing-Van der Wiel, PJ1
Wemmenhove, R1
Briscoe, MG1
Coles, GC1
Rahman, WA1
Uppal, RP2
Bhushan, C1
Lyons, ET2
Drudge, JH2
Tolliver, SC2
Stamper, S2
Kochapakdee, S1
Pandey, VS2
Pralomkarn, W1
Choldumrongkul, S1
Ngampongsai, W1
Lawpetchara, A1
Kumar, R1
Verma, SP2
Benchaoui, HA1
McKellar, QA2
Soccol, VT1
Sotomaior, C1
Souza, FP1
Castro, EA1
Pessôa Silva, MC1
Milczewski, V1
Waruiru, RM1
Hoste, H1
Chartier, C1
Steel, JW1
Hennessy, DR1
Swarnkar, CP1
Khan, FA1
Singh, D1
Bhagwan, PS1
Jasmer, DP1
Yao, C1
Rehman, A1
Johnson, S1
Zajac, AM1
Gipson, TA1
Fakae, BB1
Wakelin, D1
Crowley, JW1
Foreyt, WJ1
Bliss, DH1
Todd, AC1
Malan, FS1
Sangster, NC2
Whitlock, HV3
Kelly, JD3
Gunawan, M2
Hall, CA2
Griffin, D1
Thompson, HG1
Campbell, NJ1
Martin, IC1
Kalita, CC1
Gautam, OP1
Banerjee, DP1
Kirsch, R1
Jackson, F1
Jackson, E1
Little, S1
Coop, RL1
Russel, AJ1
Maingi, N1
Bjørn, H1
Monrad, J1
Kassuku, AA1
Nansen, P1
Williams, JC1
Knox, JW1
Barras, SA1
Hawkins, JA1
Jeannin, PC1
Bairden, K2
Gettinby, G1
Murray, M1
Urquhart, GM1
Scott, EW1
Holmes, PH1
Borgsteede, FH1
Duyn, SP1
Boisvenue, RJ1
Colestock, EL1
Hendrix, JC1
Gruner, L2
Kerboeuf, D1
Beaumont, C1
Hubert, J1
Dakkak, A1
Daoudi, A1
Ruckebusch, Y1

Trials

6 trials available for fenbendazole and Haemonchiasis

ArticleYear
Efficacy of herbal extracts and closantel against fenbendazole-resistant Haemonchus contortus.
    Journal of helminthology, 2019, Volume: 93, Issue:5

    Topics: Administration, Oral; Animals; Annona; Anthelmintics; Azadirachta; Drug Resistance; Female; Fenbenda

2019
Influence of sustained deworming pressure on the anthelmintic resistance status in strongyles of sheep under field conditions.
    Tropical animal health and production, 2016, Volume: 48, Issue:7

    Topics: Animal Husbandry; Animals; Anthelmintics; Drug Administration Schedule; Drug Resistance; Feces; Fenb

2016
Efficacy of closantel against ivermectin- and fenbendazole-resistant Haemonchus sp. in sheep in Ontario, Canada.
    Veterinary parasitology, 2016, Sep-15, Volume: 228

    Topics: Animals; Anthelmintics; Drug Evaluation; Feces; Female; Fenbendazole; Gastrointestinal Tract; Haemon

2016
Duration of anthelmintic effect of three formulations of ivermectin (oral, injectable and pour-on) against multiple anthelmintic-resistant haemonchus contortus in sheep.
    Veterinary research communications, 2007, Volume: 31, Issue:6

    Topics: Administration, Oral; Administration, Topical; Albendazole; Animals; Anthelmintics; Drug Resistance,

2007
Controlled tests of activity of several antiparasitic compounds against natural infections of Haemonchus contortus and other helminths in lambs from a flock established in 1962.
    American journal of veterinary research, 1993, Volume: 54, Issue:3

    Topics: Aging; Animals; Anthelmintics; Benzimidazoles; Cambendazole; Drug Combinations; Fenbendazole; Haemon

1993
Occurrence of resistance to anthelmintics in sheep in Paraná State, Brazil.
    The Veterinary record, 1996, Oct-26, Volume: 139, Issue:17

    Topics: Albendazole; Animals; Anthelmintics; Brazil; Drug Resistance, Multiple; Feces; Fenbendazole; Haemonc

1996

Other Studies

44 other studies available for fenbendazole and Haemonchiasis

ArticleYear
Natural resistance to worms exacerbates bovine tuberculosis severity independently of worm coinfection.
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 01-19, Volume: 118, Issue:3

    Topics: Animals; Antinematodal Agents; Buffaloes; Cattle; Coinfection; Disease Progression; Disease Resistan

2021
Recovery of fenbendazole efficacy on resistant Haemonchus contortus by management of parasite refugia and population replacement.
    Veterinary parasitology, 2019, Volume: 271

    Topics: Animal Husbandry; Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Fenbendazole; Haemonchias

2019
Gastrointestinal nematodes and anthelmintic resistance in Danish goat herds.
    Parasite (Paris, France), 2014, Volume: 21

    Topics: Animal Feed; Animal Husbandry; Animals; Anthelmintics; Denmark; Drug Resistance; Drug Utilization; F

2014
Field efficacy of four anthelmintics and confirmation of drug-resistant nematodes by controlled efficacy test and pyrosequencing on a sheep and goat farm in Denmark.
    Veterinary parasitology, 2014, Dec-15, Volume: 206, Issue:3-4

    Topics: Animals; Anthelmintics; Benzimidazoles; Denmark; Drug Resistance; Female; Fenbendazole; Goat Disease

2014
Resistance and resilience of West African Dwarf goats of the Nigerian savanna zone exposed to experimental escalating primary and challenge infections with Haemonchus contortus.
    Veterinary parasitology, 2010, Jul-15, Volume: 171, Issue:1-2

    Topics: Animals; Anthelmintics; Body Weight; Feces; Fenbendazole; Goat Diseases; Goats; Haemonchiasis; Haemo

2010
Attempts to detect synergy between vaccination and anthelmintic against a drug resistant isolate of Haemonchus contortus.
    Veterinary parasitology, 2007, Sep-30, Volume: 148, Issue:3-4

    Topics: Animals; Antibodies, Helminth; Antiparasitic Agents; Drug Resistance, Multiple; Feces; Female; Fenbe

2007
Development of benzimidazole resistance in a Haemonchus contortus strain in the Netherlands following fenbendazole treatment of ewes at parturition.
    Research in veterinary science, 1983, Volume: 34, Issue:1

    Topics: Animals; Benzimidazoles; Drug Resistance; Feces; Female; Fenbendazole; Haemonchiasis; Haemonchus; La

1983
[Observations on the effect of some measures for preventing gastrointestinal helminth infections in sheep].
    Tijdschrift voor diergeneeskunde, 1983, Jun-01, Volume: 108, Issue:11

    Topics: Animals; Anthelmintics; Benzimidazoles; Female; Fenbendazole; Haemonchiasis; Haemonchus; Intestinal

1983
Effect of anthelmintic treatment of ewes at parturition and lambs at weaning on the build up of Haemonchus contortus populations in lambs in the Netherlands.
    Research in veterinary science, 1982, Volume: 33, Issue:1

    Topics: Animals; Animals, Suckling; Benzimidazoles; Feces; Female; Fenbendazole; Haemonchiasis; Haemonchus;

1982
The speed of action of anthelmintics.
    The Veterinary record, 1980, Jan-19, Volume: 106, Issue:3

    Topics: Animals; Benzimidazoles; Biological Availability; Fenbendazole; Haemonchiasis; Levamisole; Mice; Nem

1980
Resistance to benzimidazole anthelmintics by Haemonchus contortus in goats in peninsular Malaysia.
    Veterinary parasitology, 1994, Volume: 55, Issue:1-2

    Topics: Albendazole; Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Fenbendazole; Goat Diseases; G

1994
Efficacy of closantel against fenbendazole and levamisole resistant Haemonchus contortus in small ruminants.
    Tropical animal health and production, 1993, Volume: 25, Issue:1

    Topics: Animals; Anthelmintics; Drug Resistance; Fenbendazole; Goat Diseases; Goats; Haemonchiasis; Haemonch

1993
Anthelmintic resistance in goats in southern Thailand.
    The Veterinary record, 1995, Jul-29, Volume: 137, Issue:5

    Topics: Albendazole; Animals; Anthelmintics; Drug Resistance; Feces; Fenbendazole; Goat Diseases; Goats; Hae

1995
Multiple anthelmintic resistance in Haemonchus contortus on a sheep farm in India.
    Veterinary parasitology, 1995, Volume: 60, Issue:3-4

    Topics: Albendazole; Animal Husbandry; Animals; Anthelmintics; Benzimidazoles; Drug Resistance, Multiple; Fe

1995
Interaction between fenbendazole and piperonyl butoxide: pharmacokinetic and pharmacodynamic implications.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:7

    Topics: Animals; Antinematodal Agents; Area Under Curve; Drug Synergism; Feces; Female; Fenbendazole; Goats;

1996
Anthelmintic resistance of trichostrongylids in sheep in the highveld of Zimbabwe.
    Veterinary parasitology, 1997, Volume: 68, Issue:4

    Topics: Animals; Anthelmintics; Confidence Intervals; Drug Resistance; Female; Fenbendazole; Haemonchiasis;

1997
The efficacy of closantel and rafoxanide against fenbendazole- and levamisole-resistant Haemonchus contortus in small ruminants.
    Veterinary research communications, 1997, Volume: 21, Issue:7

    Topics: Animals; Anthelmintics; Drug Resistance, Multiple; Female; Fenbendazole; Goat Diseases; Goats; Haemo

1997
Morantel resistance by Haemonchus placei in cattle.
    The Veterinary record, 1997, Nov-08, Volume: 141, Issue:19

    Topics: Animals; Antinematodal Agents; Cattle; Cattle Diseases; Drug Resistance; Female; Fenbendazole; Haemo

1997
Response to challenge infection with Haemonchus contortus and Trichostrongylus colubriformis in dairy goats. Consequences on milk production.
    Veterinary parasitology, 1998, Jan-15, Volume: 74, Issue:1

    Topics: Analysis of Variance; Animals; Antinematodal Agents; Female; Fenbendazole; Goat Diseases; Goats; Hae

1998
Influence of ruminal bypass on the pharmacokinetics and efficacy of benzimidazole anthelmintics in sheep.
    International journal for parasitology, 1999, Volume: 29, Issue:2

    Topics: Abomasum; Albendazole; Animals; Antinematodal Agents; Benzimidazoles; Drug Resistance; Fenbendazole;

1999
Further studies on anthelmintic resistance in sheep at an organised farm in arid region of Rajasthan.
    Veterinary parasitology, 1999, Mar-22, Volume: 82, Issue:1

    Topics: Animals; Antinematodal Agents; Drug Resistance; Feces; Fenbendazole; Haemonchiasis; Haemonchus; Indi

1999
Multiple lethal effects induced by a benzimidazole anthelmintic in the anterior intestine of the nematode Haemonchus contortus.
    Molecular and biochemical parasitology, 2000, Jan-05, Volume: 105, Issue:1

    Topics: Animals; Antinematodal Agents; Apoptosis; Cell Nucleus; Cytoplasmic Granules; DNA Fragmentation; Ery

2000
Multiple anthelmintic resistance in a goat herd.
    Veterinary parasitology, 2000, Volume: 87, Issue:2-3

    Topics: Administration, Oral; Administration, Topical; Animals; Anthelmintics; Drug Resistance, Multiple; Fe

2000
Expression of acquired immunity to a local isolate of Haemonchus contortus by the Nigerian West African Dwarf goat.
    Veterinary parasitology, 2002, Mar-20, Volume: 104, Issue:3

    Topics: Animals; Antinematodal Agents; Body Weight; Feces; Female; Fenbendazole; Goat Diseases; Goats; Haemo

2002
Further controlled evaluations of fenbendazole as a bovine anthelmintic.
    American journal of veterinary research, 1977, Volume: 38, Issue:5

    Topics: Animal Feed; Animals; Benzimidazoles; Cattle; Cattle Diseases; Dictyocaulus Infections; Drug Evaluat

1977
The efficacy of fenbendazole at a dosage rate of 7,5 mg/kg against nematode infestations in cattle.
    Journal of the South African Veterinary Association, 1979, Volume: 50, Issue:3

    Topics: Animals; Benzimidazoles; Cattle; Cattle Diseases; Fenbendazole; Haemonchiasis; Hookworm Infections;

1979
The effect of single and divided dose administration on the efficacy of fenbendazole against adult stages of benzimidazole resistant sheep trichostrongylids.
    Research in veterinary science, 1979, Volume: 26, Issue:1

    Topics: Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Fenbendazole; Haemonchiasis; Haemonchus; Ma

1979
The efficacy of fenbendazole and albendazole against immature and adult stages of benzimidazole-resistant sheep trichostrongylids.
    Research in veterinary science, 1979, Volume: 27, Issue:1

    Topics: Animals; Benzimidazoles; Drug Resistance; Female; Fenbendazole; Haemonchiasis; Male; Sheep; Sheep Di

1979
The effect of route of administration on the anthelmintic efficacy of benzimidazole anthelmintics in sheep infected with strains of Haemonchus contortus and Trichostrongylus colubriformis resistant or susceptible to thiabendazole.
    Research in veterinary science, 1977, Volume: 22, Issue:2

    Topics: Abomasum; Administration, Oral; Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Female; Fen

1977
Fenbendazole against haemonchosis in sheep.
    The Indian veterinary journal, 1978, Volume: 55, Issue:8

    Topics: Animals; Benzimidazoles; Female; Fenbendazole; Haemonchiasis; Male; Sheep; Sheep Diseases; Trichostr

1978
In vitro and in vivo studies on the ovicidal activity of fenbendazole.
    Research in veterinary science, 1978, Volume: 25, Issue:3

    Topics: Animals; Benzimidazoles; Fenbendazole; Haemonchiasis; Haemonchus; Sheep; Sheep Diseases; Trichostron

1978
Prevalence of anthelmintic-resistant nematodes in fibre-producing goats in Scotland.
    The Veterinary record, 1992, Sep-26, Volume: 131, Issue:13

    Topics: Animals; Drug Resistance; Feces; Female; Fenbendazole; Goat Diseases; Goats; Haemonchiasis; Ivermect

1992
Controlled tests on activity of contemporary parasiticides on natural infections of helminths in lambs, with emphasis on strains of Haemonchus contortus isolated in 1955.
    American journal of veterinary research, 1992, Volume: 53, Issue:1

    Topics: Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Feces; Fenbendazole; Haemonchiasis; Haemonc

1992
Resistance to thiabendazole, fenbendazole and levamisole in Haemonchus and Trichostrongylus species in sheep on a Kenyan farm.
    Veterinary parasitology, 1991, Volume: 39, Issue:3-4

    Topics: Animals; Drug Resistance; Feces; Fenbendazole; Haemonchiasis; Haemonchus; Intestinal Diseases, Paras

1991
Resistance to benzimidazoles in Haemonchus contortus of sheep in Tanzania.
    Acta tropica, 1990, Volume: 48, Issue:1

    Topics: Albendazole; Animals; Drug Resistance; Feces; Fenbendazole; Haemonchiasis; Haemonchus; Parasite Egg

1990
Effects of ivermectin and fenbendazole in strategic treatment of gastrointestinal nematode infections in cattle.
    American journal of veterinary research, 1990, Volume: 51, Issue:12

    Topics: Animals; Cattle; Cattle Diseases; Fenbendazole; Haemonchiasis; Ivermectin; Male; Ostertagiasis; Para

1990
Fenbendazole resistance in Haemonchus contortus of sheep.
    The Veterinary record, 1990, Jun-09, Volume: 126, Issue:23

    Topics: Animals; Benzimidazoles; Drug Resistance; Fenbendazole; Haemonchiasis; Haemonchus; Sheep; Sheep Dise

1990
Efficacy of nitroxynil against ivermectin, benzimidazole and salicylanilide resistant H contortus.
    The Veterinary record, 1990, Jun-23, Volume: 126, Issue:25

    Topics: Administration, Oral; Animals; Anthelmintics; Benzimidazoles; Drug Resistance; Feces; Fenbendazole;

1990
Benzimidazole resistance in nematodes of goats.
    The Veterinary record, 1989, May-06, Volume: 124, Issue:18

    Topics: Animals; Benzimidazoles; Drug Resistance; Feces; Fenbendazole; Goats; Haemonchiasis; Haemonchus; Par

1989
Lack of reversion of a benzimidazole resistant strain of Haemonchus contortus after six years of levamisole usage.
    Research in veterinary science, 1989, Volume: 47, Issue:2

    Topics: Animals; Benzimidazoles; Drug Resistance; Feces; Female; Fenbendazole; Haemonchiasis; Haemonchus; Le

1989
Anthelmintic activity of continuous low doses of fenbendazole into the rumen of sheep.
    Veterinary parasitology, 1988, Volume: 26, Issue:3-4

    Topics: Animals; Benzimidazoles; Female; Fenbendazole; Haemonchiasis; Haemonchus; Male; Rumen; Sheep; Sheep

1988
[Control of digestive strongylosis in small ruminants in the French West Indies: development of benzimidazole resistance and value of the reasoned management of pastures].
    Revue d'elevage et de medecine veterinaire des pays tropicaux, 1985, Volume: 38, Issue:4

    Topics: Animals; Benzimidazoles; Drug Resistance; Fenbendazole; Haemonchiasis; Humans; Intestinal Diseases,

1985
Resistance to benzimidazole of Haemonchus contortus utkalensis in sheep on Martinique.
    The Veterinary record, 1986, Mar-08, Volume: 118, Issue:10

    Topics: Animals; Benzimidazoles; Drug Resistance; Fenbendazole; Haemonchiasis; Haemonchus; Martinique; Paras

1986
Haemonchus contortus and Ostertagia circumcincta: fenbendazole treatment and abomasal permeability changes in sheep.
    American journal of veterinary research, 1985, Volume: 46, Issue:1

    Topics: Abomasum; Animals; Benzimidazoles; Electrophysiology; Fenbendazole; Haemonchiasis; Hydrogen-Ion Conc

1985