fenbendazole has been researched along with Carcinoma, Hepatocellular in 2 studies
Fenbendazole: Antinematodal benzimidazole used in veterinary medicine.
fenbendazole : A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted at positons 2 and 5 by (methoxycarbonyl)amino and phenylsulfanediyl groups, respectively. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fenbendazole (FBZ) is an anthelmintic drug known to be a potent CYP1A2 inducer." | 1.31 | Lack of modification of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced hepatocarcinogenesis in rats by fenbendazole--a CYP1A2 inducer. ( Asamoto, M; Hirose, M; Inaguma, S; Ogiso, T; Shirai, T; Suzuki, S; Takahashi, S, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, D | 1 |
| Suzuki, S | 1 |
| Takahashi, S | 1 |
| Asamoto, M | 1 |
| Inaguma, S | 1 |
| Ogiso, T | 1 |
| Hirose, M | 1 |
| Shirai, T | 1 |
2 other studies available for fenbendazole and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Fenbendazole Suppresses Growth and Induces Apoptosis of Actively Growing H4IIE Hepatocellular Carcinoma Cells via p21-Mediated Cell-Cycle Arrest.
Topics: Antinematodal Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor | 2022 |
Lack of modification of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced hepatocarcinogenesis in rats by fenbendazole--a CYP1A2 inducer.
Topics: Animals; Antinematodal Agents; Arylamine N-Acetyltransferase; Blotting, Western; Carcinogens; Carcin | 2002 |